Results 91 to 100 of about 83,543 (230)
, 2011 Phosphorylation of the yeast centrosome reveals sites of regulation and predicts complex regulation of mammalian centrosomes.
L. Bryan Ray
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The Journal of Physiology, EarlyView.Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley +1 more source
The centrosome and the DNA damage induced checkpoint.
, 2006 The centrosome, the microtubule-organizing center of the cell, acts as a localization point, where signaling molecules are able to interact. Many kinases and phosphatases critical for regulation of DNA damage signaling pathways localize to the centrosome.
Lynda Fletcher, Ruth J. Muschel
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Tetraploidy-associated centrosome overduplication in mouse early embryos
Communicative & Integrative Biology, 2018 Recently, we observed that tetraploidization of certain types of human cancer cells resulted in upregulation of centrosome duplication cycles and chronic generation of the extra centrosome. Here, we investigated whether tetraploidy-linked upregulation of
Kan Yaguchi +7 more
doaj +1 more source
HTLV-1 Tax: centrosome amplification and cancer
Retrovirology, 2006 During interphase, each cell contains a single centrosome that acts as a microtubule organizing center for cellular functions in interphase and in mitosis.
Kashanchi Fatah +2 more
doaj +1 more source
The use of deidentified organ donor testes for research
Andrology, Volume 14, Issue 8, Page 2359-2372, November 2026.Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova +4 more
wiley +1 more source
Studying centrosome formation and the consequences of centrosome loss in Drosophila melanogaster [PDF]
, 2016 Centrioles are conserved microtubule-based structures that are required for the formation of two important cellular organelles, centrosomes and cilia. Centrosomes form the poles of the mitotic spindle and consist of a pair of centrioles surrounded by a ...
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Liver International, Volume 46, Issue 11, November 2026.ABSTRACT Background & Aims Laterality disorders are rare congenital conditions caused by disruption of left–right embryonic patterning, often associated with ciliary dysfunction. Despite the identification of numerous causative genes, the molecular basis remains unresolved in many patients.
Alina Kurolap +19 more
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Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function [PDF]
, 2015 Cnn and PLP directly interact at two defined sites to coordinate the cell cycle–dependent rearrangement and scaffolding activity of the centrosome to permit normal centrosome organization, cell division, and embryonic viability.Pericentriolar material ...
Poulton, John S. +13 more
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