Results 121 to 130 of about 82,885 (231)
Arabidopsis AUGMIN8 Contains Two Independent Microtubule Association Domains
ABSTRACT Plant cells create a plasma membrane‐associated network of microtubules that are nucleated by γ‐tubulin ring complexes primarily through microtubule‐dependent microtubule nucleation (MDMN). This dynamic array organizes into specific patterns in response to developmental and environmental cues to influence primary cell wall construction.
Naveen K. Chana +2 more
wiley +1 more source
Centrosome Remodelling in Evolution
The centrosome is the major microtubule organizing centre (MTOC) in animal cells. The canonical centrosome is composed of two centrioles surrounded by a pericentriolar matrix (PCM).
Daisuke Ito, Mónica Bettencourt-Dias
core +1 more source
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng +9 more
wiley +1 more source
Background At the onset of mitosis, the centrosome expands and matures, acquiring enhanced activities for microtubule nucleation and assembly of a functional bipolar mitotic spindle.
Chieh-Ting Fang +3 more
doaj +1 more source
The evolutionary origins of streptophyte multicellularity
The phylogeny of streptophytes and the deep origin of branching filamentous growth. Summary Over their more than 1 billion years of evolutionary history, streptophytes have repeatedly transitioned between unicellular, simple multicellular and complex multicellular forms.
Tatyana Darienko +10 more
wiley +1 more source
CP91 is a component of the Dictyostelium centrosome involved in centrosome biogenesis
The Dictyostelium centrosome is a model for acentriolar centrosomes and it consists of a three-layered core structure surrounded by a corona harboring microtubule nucleation complexes. Its core structure duplicates once per cell cycle at the G2/M transition.
Putzler, Sascha +2 more
openaire +2 more sources
The centrosome is an actin-organizing centre.
International audienceMicrotubules and actin filaments are the two main cytoskeleton networks supporting intracellular architecture and cell polarity.
Sillibourne, James +13 more
core +1 more source
Hypoxia-Induced Centrosome Loss in Epithelial Cells
Centrosome loss has recently been reported as a phenotype of prostate cancer. Hypoxia, an environmental condition seen commonly in prostate cancer, can cause centrosome loss in the immortalized prostate epithelial cell line, RWPE1.
Loertscher, Emily
core +2 more sources
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
The Secret (Mitotic) Life of Clathrin
A perspective on the function of clathrin at the mitotic spindle during cell division. ABSTRACT The discovery of clathrin was a foundational event in membrane traffic research. Its identification as the major protein component of the coat that surrounds endocytic vesicles kickstarted the biochemical and molecular characterization of endocytosis. During
Stephen J. Royle
wiley +1 more source

