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The γ-TuRC: mastermind of multipurpose actions at the centrosome. [PDF]

Cell Mol Life Sci
Mukhopadhyay S, Gao Q, Manna TK, Schiebel E.   +3 more
europepmc   +1 more source

Organelle biogenesis on a synthetic bead

Chang C, Peng M, Blaya-Martinez L, Wong S, Mohamad N, Xiao B, Monteiro JM, Harrison T, Raff JW.   +8 more
europepmc   +1 more source

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Centrosomal and non‐centrosomal microtubules

Biology of the Cell, 1999
While microtubule (MT) arrays in cells are often focused at the centrosome, a variety of cell types contain a substantial number of non‐centrosomal MTs. Epithelial cells, neurons, and muscle cells all contain arrays of non‐centrosomal MTs that are critical for these cells' specialized functions. There are several routes by which non‐centrosomal MTs can
T J, Keating, G G, Borisy
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Aurora A, centrosome structure, and the centrosome cycle

Environmental and Molecular Mutagenesis, 2009
AbstractThe centrosome, also known as the microtubule organizing center of the cell, is a membrane‐less organelle composed of a pair of barrel‐shaped centrioles surrounded by electron‐dense pericentriolar material. The centrosome progresses through the centrosome cycle in step with the cell cycle such that centrosomes are duplicated in time to serve as
Kara B, Lukasiewicz, Wilma L, Lingle
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Centrosomes and Centrosome Equivalents in Other Systems

2022
Stem cells are important to sustain tissue growth during development, to repair damaged tissue after injury, and to maintain homeostasis during adulthood. Precisely programmed stem cell renewal and differentiation is critical, as failure in balance can lead to tumorigenesis as a result of over-proliferation or to degeneration as a result of decline in ...
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Centrosomes in Reproduction

2022
Centrosome functions are vitally important for all aspects of reproduction with essential functions during meiosis, fertilization, cell division, centrosome remodeling during cellular polarization for tissue formation, and all stages of subsequent embryo development.
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