Results 131 to 140 of about 82,885 (231)
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Experimental Physiology, Volume 111, Issue 9, Page 4015-4040, 1 September 2026.Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
GM130 controls Golgi-centrosome proximity.
, 2019 A. Wild-type and GM130 KO cells were stained for γ-tubulin and Golgin-84 to visualize the centrosome and the Golgi, respectively. B. Left: Graph showing the percentage of cells with increased Golgi (GA)—centrosome distance.
Kati Tormanen (6589415) +4 more
core +1 more source
The LINC complex ensures accurate centrosome positioning during prophase
Life Science AllianceCentrosome positioning in prophase is essential for efficient spindle assembly. Here, we show that centrosome positioning requires LINC complex–mediated loading of dynein on the nuclear envelope.
Joana T Lima +2 more
doaj +1 more source
Delayed centrosome maturation causes asymmetric particle partitioning.
, 2012 (A) Time series of dynein distribution with ∼1 hr time delay between the centrosome maturation (also see Movie S3). During the simulated duration of 3000 s, the number of microtubules organized by the dominant centrosome increases from 200 to 800.
Jennifer Lippincott-Schwartz (171711) +2 more
core +1 more source
The arithmetic of centrosome biogenesis [PDF]
How do cells regulate centrosome number? A canonical duplication cycle generates two centrosomes from one in most proliferating cells. Centrioles are key to this process, and molecules such as centrins, SAS-4 and ZYG-1 govern daughter centriole formation.
Delattre, Marie, Gönczy, Pierre
core +2 more sources
Centrosome isolation from cultured bladder cancer cells--p53 mutation and centrosome hyperamplification [PDF]
, 2003 膀胱癌細胞株を用いて中心体の分離を試み, 中心体複製周期をコントロールするnucleophosmin/B23(NPM)の中心体の局在を検討した.ヒト膀胱癌細胞株(RT-4, HT-1197, HT-1376)を用いた.RT-4は中心体の複製周期が保たれている細胞株であり, HT-1197, HT-1376は中心体過剰複製を認める細胞株であった.HT-1197, HT-1376においては, 3個以上の中心体も観察できた.RT-4とHT-1197において ...
森山, 学 +6 more
core
Scientific ReportsCentrosomes are critical organelles associated with the nucleus, consisting of a pair of centrioles surrounded by a cloud of pericentriolar material. They serve as key nucleation sites for microtubule arrays and are essential for positioning the nucleus ...
Shayne M. Plourde +2 more
doaj +1 more source
Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis
, 2015 Nek5 is a poorly characterized member of the NIMA-related kinase family, other members of which play roles in cell cycle progression and primary cilia function.
Navdeep K. Sahota (7607171) +14 more
core +1 more source
Molecular mechanisms underlying centrosome disjunction
, 2019 As a major microtubule-organizing center in mammalian cells, the centrosome consists of two centrioles that are surrounded by the pericentriolar material.
Au, Kin Chung Franco
core
Golgi and centrosome: building a functional partnership.
, 2010 The mammalian Golgi apparatus is characterized by a ribbon-like organization adjacent to the centrosome during interphase and extensive fragmentation and dispersal away from the centrosome during mitosis.
Colanzi A, Sütterlin C
core