Results 101 to 110 of about 418 (139)

Antibiofilm approaches as a new paradigm for treating infections. [PDF]

open access: yesProg Biomed Eng (Bristol)
Reffuveille F   +4 more
europepmc   +1 more source

Antibiotic Mechanisms and Resistance: Molecular Insights and Therapeutic Strategies. [PDF]

open access: yesAntibiotics (Basel)
Ma H   +7 more
europepmc   +1 more source

Detection and identification of pathogens using agents targeting the bacterial cell wall. [PDF]

open access: yesFolia Microbiol (Praha)
Zhydzetski A   +3 more
europepmc   +1 more source

Depolarization, Bacterial Membrane Composition, and the Antimicrobial Action of Ceragenins. [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2010
Ceragenins are cholic acid-derived antimicrobial agents that mimic the activity of endogenous antimicrobial peptides. Ceragenins target bacterial membranes, yet the consequences of these interactions have not been fully elucidated.
Paul B Savage   +2 more
exaly   +4 more sources

Susceptibility of Colistin-Resistant, Gram-Negative Bacteria to Antimicrobial Peptides and Ceragenins. [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2017
The susceptibility of colistin-resistant clinical isolates of Klebsiella pneumoniae to ceragenins and antimicrobial peptides (AMPs) suggests that there is little to no cross-resistance between colistin and ceragenins/AMPs and that
Mehdi Forouzan   +2 more
exaly   +4 more sources

Comparative in Vitro Antimicrobial Activities of CSA-142 and CSA-192, Second-Generation Ceragenins, With CSA-13 Against Various Microorganisms

open access: yesJournal of Chemotherapy, 2018
Ceragenins, a novel family of antibiotics, are cationic derivatives of cholic acid and display broad-spectrum antimicrobial activities. Multiple ceragenins have been synthesized and studied, and most published data are with ceragenin CSA-13.
Özlem Oyardı   +2 more
exaly   +3 more sources
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The application of ceragenins to orthopedic surgery and medicine

Journal of Orthopaedic Research, 2020
AbstractOsteomyelitis and infections associated with orthopedic implants represent a significant burden of disease worldwide. Ceragenins (CSAs) are a relatively new class of small‐molecule antimicrobials that target a broad range of Gram‐positive and Gram‐negative bacteria as well as fungi, viruses, and parasites.
Aiken Dao   +5 more
openaire   +2 more sources

Ceragenins: Cholic Acid-Based Mimics of Antimicrobial Peptides

Accounts of Chemical Research, 2008
The prevalence of drug-resistant bacteria drives the quest for new antimicrobials, including those that are not expected to readily engender resistance. One option is to mimic Nature's most ubiquitous means of controlling bacterial growth, antimicrobial peptides, which have evolved over eons.
Lai, Xin-Zhong   +8 more
openaire   +2 more sources

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