Results 111 to 120 of about 418 (139)
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Ceragenin Mediated Selectivity of Antimicrobial Silver Nanoparticles
ACS Applied Materials & Interfaces, 2014The understanding that common broad-spectrum antimicrobials disrupt natural microbial flora important in acquiring nutrients and preventing infection has resulted in a paradigm shift favoring more selective antimicrobials. This work explores silver nanoparticles conjugated with ceragenin, or cationic antimicrobials (CSA-SNPs), as a potential Gram ...
Mark A, Hoppens +7 more
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Biochimica Et Biophysica Acta - Biomembranes, 2007 Ceragenins are cationic bile salt derivatives having antimicrobial activity. The interactions of several ceragenins with phospholipid bilayers were tested in different systems. The ceragenins are capable of forming specific associations with several phospholipid species that may be involved with their antimicrobial action.
Paul B Savage +2 more
exaly +3 more sources
Ceragenins (Cationic Steroid Compounds), a Novel Class of Antimicrobial Agents
Drug News & Perspectives, 2008Ceragenins are a group of cholic acid derivatives that have been chemically modified to make them cationic amphiphiles. Several of these derivatives exhibit antimicrobial activity against a broad range of bacteria. These compounds have advantages over cationic amphipathic peptides in that they are resistant to proteolysis and they incorporate stably ...
Richard M, Epand +2 more
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Maghemite, silver, ceragenin conjugate particles for selective binding and contrast of bacteria
Journal of Colloid and Interface Science, 2014New synthesis techniques are providing increasing control over many inorganic nanoparticle characteristics, facilitating the creation of new multifunctional theranostics. This report proposes the synthesis and testing of a combination nanoparticle comprised of a maghemite core for enhanced T2 MRI contrast diagnostics, a colloidal silver shell acting as
Mark A, Hoppens +8 more
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Ceragenin CSA‐13 exhibits antimicrobial activity against cariogenic and periodontopathic bacteria
Oral Microbiology and Immunology, 2009Introduction: Ceragenin CSA‐13 is a bile‐acid‐based mimic of endogenous antimicrobial peptides and shares a mechanism of action with many of these antimicrobial agents. Because CSA‐13 is not peptide based, it is not a substrate for the proteases that are found in the oral cavity, which are capable of degrading antimicrobial peptides.
E, Isogai +4 more
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Antibiofilm Potential of Ceragenins Against Vancomycin-Resistant Enterococcus spp.
Fabad Journal of Pharmaceutical SciencesEnterococcus spp., especially vancomycin-resistant enterococci (VRE), are listed by the World Health Organization as priority pathogens requiring new antimicrobial treatments.Ceragenins (CSAs) are a novel class of broad-spectrum antimicrobials that are relatively easy and cost-effective to produce. This study evaluated the antibacterial and antibiofilm
Müzeyyen Aydın +5 more
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