Fatty acid transport protein 2 interacts with ceramide synthase 2 to promote ceramide synthesis. [PDF]
J Biol Chem, 2022 Dihydroceramide is a lipid molecule generated via the action of (dihydro)ceramide synthases (CerSs), which use two substrates, namely sphinganine and fatty acyl-CoAs. Sphinganine is generated via the sequential activity of two integral membrane proteins located in the endoplasmic reticulum.
Kim JL +5 more
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A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis [PDF]
, 2017 Bianca Williams +11 more
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Ceramide synthase 6 mediates sex-specific metabolic response to dietary folic acid in mice. [PDF]
J Nutr Biochem, 2021 Barron K, Ogretmen B, Krupenko N.
europepmc +1 more source
Ceramide synthase 2 deletion decreases the infectivity of HIV-1. [PDF]
J Biol Chem, 2021 Barklis E +11 more
europepmc +1 more source
Developmentally Regulated Ceramide Synthase 6 Increases Mitochondrial Ca2+ Loading Capacity and Promotes Apoptosis [PDF]
, 2010 Sergei A. Novgorodov +6 more
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Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway. [PDF]
Leukemia, 2022 Sofi MH +18 more
europepmc +1 more source
Loss of ceramide synthase 5 inhibits the development of experimentally induced aortic valve stenosis [PDF]
Laurine Reese +9 more
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Silencing of ceramide synthase 2 in hepatocytes modulates plasma ceramide biomarkers predictive of cardiovascular death. [PDF]
Mol Ther, 2022 Schmidt S +11 more
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Glucosylceramide synthesis and synthase expression protect against ceramide-induced stress [PDF]
, 2002 Yoshikazu Uchida +8 more
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