Results 91 to 100 of about 194,964 (167)
Embryonic expression of Drosophila ceramide synthase schlank in developing gut, CNS and PNS.
, 2011 Schlank is a member of the highly conserved ceramide synthase family and controls growth and body fat in Drosophila. Ceramide synthases are key enzymes in the sphingolipid de novo synthesis pathway.
André Voelzmann +3 more
core +1 more source
MedComm, Volume 7, Issue 10, October 2026.Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna +3 more
wiley +1 more source
Left panel: Time series estimates of ceramide synthase activities.
, 2016 Each plot represents the ceramide synthase activities for a specific ceramide species. Gray stars represent individual simulation results and blue lines are averaged simulated activities.
Luis L. Fonseca (416505) +3 more
core +1 more source
MedComm, Volume 7, Issue 10, October 2026.This review systematically covers three core dimensions of brown adipose tissue (BAT): multilayered regulatory mechanisms governing brown adipocyte differentiation and phenotypic identity, physiological functions and signaling pathways in mediating thermogenesis and systemic metabolic crosstalk between BAT and multiple organs, and emerging clinical in ...
Xiaoli Deng +4 more
wiley +1 more source
Biophysical studies of lipid membranes by solid state NMR and molecular dynamics simulations [PDF]
, 2013 Biological membranes separate the cell interior from the outside and have diverse functions from signal transduction, apoptosis to transportations of ions and small molecules in and out of the cell.
Dutagaci, Bercem
core
Journal of Lipid Research, 2005 Addition of exogenous ceramide causes a significant displacement of cholesterol in lipid raft model membranes. However, whether ceramide-induced cholesterol displacement is sufficient to alter the protein composition of caveolin-enriched lipid raft ...
Cuijuan Yu +2 more
doaj +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9346-9355, October 2026.ABSTRACT Aim Cardiovascular disease (CVD) is the leading cause of mortality in individuals with diabetes. Diabetic kidney disease, closely related to CVD risk, is prevalent in up to 40% of this population. Emerging evidence suggests ceramide lipids as accurate biomarkers for CVD.
Kristina Pigsborg +10 more
wiley +1 more source
Protection of C. elegans from anoxia by HYL-2 ceramide synthase
, 2009 Oxygen deprivation is rapidly deleterious for most organisms. However, Caenorhabditis elegans has developed the ability to survive anoxia for at least 48 hours. Mutations in the DAF-2/DAF-16 insulin-like signaling pathway promote such survival.
Fornallaz-Mulhauser, M +22 more
core +1 more source
, 2020 Ceramide synthase 5 is one of six enzymes that catalyze the production of ceramides from sphingosine or sphinganine. Ceramides are important components of cell membranes and act as signaling molecules.
Dominique Thomas +11 more
core +1 more source
Methods and Protocols, 2019 Sphingolipid metabolism is an important process in sustaining the growth needs of rapidly dividing cancer cells. Enzymes that synthesize sphingolipids have become attractive targets in cancer pharmacology.
Srinath Pashikanti +7 more
doaj +1 more source