Results 101 to 110 of about 338,348 (241)
Regulation of neutral ceramidase in glomerular messangial cells
, 2009 During the past several years, ceramide has emerged as an important second messenger triggering cell responses including proliferation, differentiation, growth arrest and apoptosis.
Franzen, Rochus
core
Biological functions of Sphingomyelin synthase related protein and Ceramide synthase 4 investigated with transgenic mouse mutants [PDF]
, 2017 Previously, it was reported that the catalytic activity of the sphingomyelin synthase related protein (SMSr) is essential to prevent ceramide accumulation and disruption of the early secretory pathway in cultured HeLa cells. The enzymatic product of SMSr
Bickert, Andreas
core
Ceramide synthase 1 is regulated by proteasomal mediated turnover
, 2009 Ceramide is an important bioactive lipid, intimately involved in many cellular functions, including the regulation of cell death, and in cancer and chemotherapy.
Alexander, Hannah +6 more
core +1 more source
Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola
Insect Molecular Biology, EarlyView.Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez +1 more
wiley +1 more source
Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas [PDF]
, 2009 (Dihydro) ceramide synthase 2 (cers2, formerly called lass2) is the most abundantly expressed member of the ceramide synthase gene family, which includes six isoforms in mice.
Degen, Joachim +8 more
core
Sphingolipid Effects on the Plasma Membrane Produced by Addition of Fumonisin B1 to Maize Embryos
Plants, 2020 Fumonisin B1 is a mycotoxin produced by Fusarium verticillioides that modifies the membrane properties from animal cells and inhibits complex sphingolipids synthesis through the inhibition of ceramide synthase.
Nora A. Gutiérrez-Nájera +8 more
doaj +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis
Scientific Reports, 2017 Sphingolipids regulate critical cellular processes including inflammation. Ceramide, which serves a central role in sphingolipid metabolism, is generated by six ceramide synthases (CerS) that differ in substrate specificity.
Matthew J. Scheffel +7 more
semanticscholar +1 more source
The Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song +6 more
wiley +1 more source
یافتههای نوین در علوم زیستی, 2016 Carnosic acid and Rosmarinic acid are family of polyphenols that are found in Rosmary plant. They have property biological behaviors such as anti-cancer, anti-viral and anti-oxidants.
Narges Najjarpour +1 more
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