Results 101 to 110 of about 138,758 (293)

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, EarlyView.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

5-Hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology

, 2019
5-Hydroxytryptophan (5-HTP), a precursor of serotonin, is therapeutically used for several psychiatric disorders such as anxiety and depression in the clinic.
Muresanu, Dafin Fior,, Dafin Fior Muresanu, Sharma, Aruna,, Smith, Mark A.,, Mark A. Smith, Sharma, Hari Shanker,, Rudy J. Castellani, Hari Shanker Sharma, Aruna Sharma, Dey, Prasanta Kumar,, Prasanta Kumar Dey, Castellani, Rudy J.,   +11 more
core   +1 more source

Treatment of a Large Cohort of Childhood Chronic Noninfectious Uveitis in a Multicentric Large Study: Adalimumab Versus Methotrexate as First‐Line Therapy

Arthritis &Rheumatology, EarlyView.
Objective Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in juvenile idiopathic arthritis–associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheumatology and ophthalmology units at Florence, Italy ...
Ilaria Maccora, Catherine Guly, Cinzia de Libero, Giulia Carreras, Athimalaipet V. Ramanan, Gabriele Simonini   +5 more
wiley   +1 more source

Profile of intravenous glyburide for the prevention of cerebral edema following large hemispheric infarction: evidence to date

, 2018
Zachary A King,1 Kevin N Sheth,1 W Taylor Kimberly,2 J Marc Simard3 1Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Yale University School of Medicine, New Haven, CT, USA; 2Department of Neurology, Division of ...
Sheth KN, Simard JM, King ZA, Kimberly WT   +3 more
core  

Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials

Acute intracerebral hemorrhage is the most devastating stroke subtype and is associated with significant morbidity and mortality. Poor prognosis is associated with primary brain injury from the presenting hematoma, and despite advances in clinical trials
Kirkman, Matthew A., Roffe, Christine, Appleton, Jason P., Tan, Chia Wei, Nguyen, Thanh N., Chan, Siang Liang, Bath, Philip M., England, Timothy J., Hollingworth, Milo, Sprigg, Nikola, Dawson, Jesse, Werring, David J., Campos, Paula Bermell, Law, ZheKang, Krishnan, Kailash, Macleod, Mary Joan, Bayraktutan, Ulvi   +16 more
core   +1 more source

Supine‐Position Shoulder Arthroscopy Using the Anterior Portal as the Initial Approach

Arthroscopy Techniques, EarlyView.
Abstract Traditional shoulder arthroscopy mostly adopts the beach chair position or lateral decubitus position. Beach chair position is associated with the risk of cerebral hypoperfusion due to the vertical distance between the carotid artery and the heart, whereas lateral decubitus may induce brachial plexus palsy caused by excessive traction.
Weidong Wang, Yingbiao Wang, Sen Li, Mu Gao   +3 more
wiley   +1 more source

Hipoxia causada por edema cerebral

, 2009
Tres imágenes de un cerebro con hipoxia causada por un edema cerebral.Three pictures of a brain with hypoxia caused by a cerebral ...
Iglesias Rozas, José Rafael, 1942-
core  

Cerebral edema following experimental subarachnoid hemorrhage.

, 1982
The development of cerebral edema after experimental subarachnoid hemorrhage (SAH) was studied in cats by determining regional brain tissue water content with the microgravimetric technique as well as the drying-weighing method.
J Schramm, M Brock, T Shigeno, S Shigeno, E Fritschka, J Cervoś-Navarro   +5 more
core   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source