Results 81 to 90 of about 138,758 (293)
Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation [PDF]
, 2010 Introduction: Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion in-jury.
Meybohm, Patrick +8 more
core +1 more source
AGING MEDICINE, EarlyView.Frailty was associated with decreased gray and white matter brain volumes in older adults. Synthetic MRI further revealed relaxometry alterations correlated with frailty severity across multiple clinical scales. ABSTRACT Objectives Frailty, a common condition in the elderly, is characterized by a decline in physiological reserves and an increased ...
Yuhui Chen +7 more
wiley +1 more source
Case Reports in Endocrinology, 2016 A 13-year-old adolescent boy with type 1 diabetes mellitus (1b) presented with diabetic ketoacidosis (DKA) and cerebral edema. Grossly lipemic serum and lipemia retinals due to extremely high triglyceride (TG) level were observed without evidence of ...
Tansit Saengkaew +3 more
doaj +1 more source
Role of aquaporin-4 in cerebral edema and stroke.
, 2009 Cerebral edema plays a central role in the pathophysiology of many diseases of the central nervous system (CNS) including ischemia, trauma, tumors, inflammation, and metabolic disturbances. The formation of cerebral edema results in an increase in tissue
Stiver, Shirley +3 more
core +1 more source
The 9th International RASopathies Symposium
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source
, 2005 Cerebral edema is an increase in brain volume caused by increased tissue water content. The causes of cerebral edema include an increase in intravascular pressure, damage to and increased permeability of the cerebral vascular wall, and a decrease in ...
Barrett J. Katz, MD, MBA
core
Predicting cerebral edema in ischemic stroke patients
, 2019 Objectives: To produce a scoring system for predicting the development of edema in ischemic stroke patients without edema on admission. Methods: This retrospective study included 572 ischemic stroke patients (73.3 ± 13.0 years, 300 male) without ...
Puddu G. M. +7 more
core +1 more source
Expanding the Phenotype of TUFM‐Related Combined Oxidative Phosphorylation Deficiency 4
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier +2 more
wiley +1 more source
A Case of Multiple Mitochondrial Dysfunctions Syndrome 1 and Review of the Literature
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Multiple mitochondrial dysfunctions syndrome 1 (MMDS1, MIM #605711) due to NFU1 gene defects is an ultra‐rare autosomal recessive inborn error of metabolism associated with reduced function of NFU1 iron–sulfur cluster (ISC) scaffold protein.
Charles R. DiFalco +6 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim +12 more
wiley +1 more source