Results 71 to 80 of about 218,307 (293)

Matrix metalloproteinases at key junctions in the pathomechanism of stroke [PDF]

, 2011
Matrix metalloproteinases play a crucial role in the remodelling of the extracellular matrix through direct degradation of its structural proteins and control of extracellular signaling.
Amento, Ang, Asahi, Asahi, Barkho, Bergers, Bini, Cao, Cardone, Chinopoulos, Cunningham, Denker, Dong, Fabunmi, Fisher, Frisch, Galis, Galis, Galis, Galis, Gidday, Godin, Gross, Gu, Gu, Gurney, Haas, Haddad, Halliwell, Hamann, Harkness, Herman, Hornig, Hyslop, Itoh, Kumura, Langton, Lapchak, Larsen, Lee, Lelongt, Loftus, Lucivero, Luttun, McQuibban, Meredith, Montaner, Montaner, Nagase, Nagel, Nagy, Nagy, Nikkari, Pagenstecher, Qi, Rajagopalan, Ramos, Rekhter, Rolfe, Romanic, Rosell, Rosenberg, Rosenberg, Rosenberg, Rosenberg, Sarén, Sato, Seo, Shrivastava, Shubayev, Siao, Sole, Sottrup, Sternlicht, Strongin, Sukhova, Suzuki, Suzuki, Svedin, Tsuji, Turner, Van, Vogel, Wang, Wang, Webersinke, Yepes, Ying, Zhang, Zhang, Zhang, Zhao   +91 more
core   +1 more source

Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring

Advanced Materials Technologies, EarlyView.
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim, Yu‐Jen Cheng, Tianyi Li, Nathan White, Xu Wang, Kristyn Ringgold, Lauren Neidig, Younghoon Kwon, Jae‐Hyun Chung   +8 more
wiley   +1 more source

Brain CT Scan Diagnostic and Prognostic Value in Patients With Acute Liver Failure and Cerebral Edema: A Multicenter Cohort Study

Critical Care Explorations
OBJECTIVE:. Patients with acute liver failure (ALF) may develop cerebral edema. We aimed to study the CT scan diagnostic and prognostic value among patients with ALF and cerebral edema. DESIGN:. International multicenter retrospective cohort. SETTING:. U.
Filipe S. Cardoso, MD, MSc, William M. Lee, MD, Constantine J. Karvellas, MD, MSc, U.S. Acute Liver Failure Study Group, W.M. Lee, MD, Anne M. Larson, MD, Iris Liou, MD, Oren Fix, MD, Michael Schilsky, MD, Timothy McCashland, MD, J. Eileen Hay, MBBS, Natalie Murray, MD, A. Obaid S. Shaikh, MD, Andres Blei, MD, Daniel Ganger, MD, Atif Zaman, MD, Steven H.B. Han, MD, Robert Fontana, MD, Brendan McGuire, MD, Raymond T. Chung, MD, Alastair Smith, MB, ChB, Robert Brown, MD, Jeffrey Crippin, MD, Adrian Reuben, MBBS, Santiago Munoz, MD, Rajender Reddy, MD, R. Todd Stravitz, MD, Lorenzo Rossaro, MD, Raj Satyanarayana, MD, Tarek Hassanein, MD, Constantine J. Karvellas, MD, Jodi Olson, MD, Ram Subramanian, MD, James Hanje, MD, Bilal Hameed, MD, Grace Samuel, Ezmina Lalani, Carla Pezzia, Corron Sanders, PhD, Nahid Attar, Linda S. Hynan, PhD, Valerie Durkalski, PhD, Wenle Zhao, PhD, Jaime Speiser, Catherine Dillon, Holly Battenhouse, Michelle Gottfried   +46 more
doaj   +1 more source

Translational perspectives on perfusion-diffusion mismatch in ischemic stroke [PDF]

, 2013
Magnetic resonance imaging has tremendous potential to illuminate ischemic stroke pathophysiology and guide rational treatment decisions. Clinical applications to date have been largely limited to trials.
Campbell, Bruce C. V., Macrae, I. Mhairi
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Blood Flow and Continuous EEG Changes during Symptomatic Plateau Waves

Brain Sciences, 2018
Benign meningiomas uncommonly lead to significant cerebral edema, with only a few cases previously reported in the medical literature. The present study describes the case of a 49-year-old female who had a meningioma resection. She subsequently developed
Natalie Kreitzer, Maggie Huynh, Brandon Foreman   +2 more
doaj   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

Magnetic Resonance Imaging Pilot Study of Intravenous Glyburide in Traumatic Brain Injury. [PDF]

, 2020
Pre-clinical studies of traumatic brain injury (TBI) show that glyburide reduces edema and hemorrhagic progression of contusions. We conducted a small Phase II, three-institution, randomized placebo-controlled trial of subjects with TBI to assess the ...
Aldrich, Christina, Eisenberg, Howard M, Hayman, Erik G, He, Feng, Jain, Sonia, Okonkwo, David O, Pasternak, Ofer, Shenton, Martha E, Simard, J Marc   +8 more
core  

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

CLINICAL PATHOPHYSIOLOGY OF CEREBRAL EDEMA (part 2)

Вестник анестезиологии и реаниматологии, 2018
The article gives the updated understanding of the physiology of cerebral fluid exchange and pathophysiology of cerebral edema. The first part of the article has been devoted to a description of the mechanisms of fluid and electrolyte exchange in health ...
A. A. Zadvornov, A. V. Golomidov, E. V. Grigoriev   +2 more
doaj   +1 more source