Results 91 to 100 of about 138,758 (293)

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao   +5 more
wiley   +1 more source

Edema cerebral y hemorragia subaracnoidea

open access: yes, 2009
Dos imágenes de un edema cerebral y una hemorragia subaracnoidea en un niño.Two pictures of a cerebral edema and a subarachnoidal hemorrhage in a ...
Iglesias Rozas, José Rafael, 1942-
core  

Ischemic cerebral edema. A review.

open access: yes, 1979
The genesis of ischemic cerebral edema is multi-factorial and the relative importance of these many factors varies throughout the lesion and with time. The initial event is intracellular edema which may be followed by extracellular edema.
M D O'Brien
core   +1 more source

Research progress on biomarkers of traumatic brain injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen   +8 more
wiley   +1 more source

Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis

open access: yesAnnals of Neurology, EarlyView.
Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi   +33 more
wiley   +1 more source

Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice [PDF]

open access: yes, 2017
High altitude cerebral edema (HACE) is a life-threatening illness that develops during the rapid ascent to high altitudes, but its underlying mechanisms remain unclear. Growing evidence has implicated inflammation in the susceptibility to and development
Chen
core   +1 more source

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

open access: yesAnnals of Neurology, EarlyView.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones   +54 more
wiley   +1 more source

Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile

open access: yesAnnals of Neurology, EarlyView.
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale   +17 more
wiley   +1 more source

Hemispheric Cerebral Edema [PDF]

open access: yesThe American Journal of Medicine, 2017
Ina, Dubin, Yosef, Drahy, Ami, Schattner
openaire   +2 more sources

Antibodies to Dynorphin A (1–17) Attenuate Closed Head Injury Induced Blood–Brain Barrier Disruption, Brain Edema Formation and Brain Pathology in the Rat

open access: yes, 2009
The potential neuroprotective efficacy of dynorphin A antiserum on BBB dysfunction, edema formation and brain pathology was examined in a closed head injury (CHI) model in the rat.
S. Mohanty   +11 more
core   +1 more source

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