Results 1 to 10 of about 366,900 (304)
Neuroprotective effects of zonisamide on cerebral ischemia injury via inhibition of neuronal apoptosis [PDF]
Brazilian Journal of Medical and Biological Research, 2021 It is known that neuronal apoptosis contributes to pathology of cerebral ischemia injury. Zonisamide (ZNS) has shown anti-apoptosis effects in recent studies.
Junna He +6 more
doaj +1 more source
Journal of Neuroinflammation, 2021 Background It is suggested that neuroinflammation, in which activated microglial cells play a relevant role, contributes to the development of Parkinson’s disease (PD).
Neus Rabaneda-Lombarte +5 more
doaj +1 more source
npj Parkinson's Disease, 2022 Neuroinflammation, in which activated microglia are involved, appears to contribute to the development of Parkinson’s disease (PD). However, the role of microglial activation and the mechanisms governing this process remain uncertain.
Neus Rabaneda-Lombarte +8 more
doaj +1 more source
Effects and Mechanisms of Exosomes from Different Sources in Cerebral Ischemia
Cells, 2022 Cerebral ischemia refers to the symptom of insufficient blood supply to the brain. Cells of many different origins participate in the process of repairing damage after cerebral ischemia occurs, in which exosomes secreted by the cells play important roles.
Ruoxi Xie +4 more
doaj +1 more source
The Alterations in Mitochondrial Dynamics Following Cerebral Ischemia/Reperfusion Injury
Antioxidants, 2021 Cerebral ischemia results in a poor oxygen supply and cerebral infarction. Reperfusion to the ischemic area is the best therapeutic approach. Although reperfusion after ischemia has beneficial effects, it also causes ischemia/reperfusion (I/R) injury ...
Jirapong Vongsfak +5 more
doaj +1 more source
Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]
, 2013 Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken +13 more
core +11 more sources
Journal of Medical Science, 2021 Aim. Measure of the histological changes in neurons in the parietal cortex and hippocampus of rats with partial, subtotal, stepwise subtotal, and total cerebral ischemia. Material and Methods. Studies were performed on 84 rats. Partial cerebral ischemia
Lizaveta I. Bon, Nataliya Y. Maksimovich
doaj +1 more source
Establishment and Evaluation of a Monkey Acute Cerebral Ischemia Model [PDF]
Clinics, 2020 OBJECTIVES: Cerebral ischemia seriously threatens human health and is characterized by high rates of incidence, disability and death. Developing an ideal animal model of cerebral ischemia that reflects the human clinical features is critical for ...
Li Yan +11 more
doaj +1 more source
AG490 protects cerebral ischemia/reperfusion injury via inhibiting the JAK2/3 signaling pathway
Brain and Behavior, 2021 Background Cerebral ischemia/reperfusion injury is a severe problem in patients with brain ischemia. Brain injury caused by the immune response is important in the pathogenesis of cerebral ischemia/reperfusion injury and immune pathways.
Lichao Fan, Lichun Zhou
doaj +1 more source
Nrf2 Regulates Oxidative Stress and Its Role in Cerebral Ischemic Stroke
Antioxidants, 2022 Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain, which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc.
Lei Wang +7 more
doaj +1 more source