Nrf2 Regulates Oxidative Stress and Its Role in Cerebral Ischemic Stroke
Antioxidants, 2022 Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain, which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc.
Lei Wang +7 more
doaj +1 more source
Neuroprotective and anti-inflammatory effects of myricetin 3-glucoside in a rat model of cerebral ischemia [PDF]
, 2020 Purpose: To investigate the effect of myricetin 3-glucoside (M3GLS) on middle cerebral artery occlusion (MCAO)-induced cerebral ischemia in a rat model, and the mechanism of action involved.Methods: A cerebral ischemia rat model was established using ...
Ma, Jing +3 more
core +2 more sources
PLoS ONE, 2021 Cerebral ischemia causes tissue death owing to occlusion of the cerebral blood vessels, and cerebral ischemia activates mitogen-activated protein kinase (MAPK) and induces secretion of pro-inflammatory cytokines.
Il-Gyu Ko +7 more
doaj +1 more source
Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages
Frontiers in Cellular Neuroscience, 2017 In the brain of patients with multiple sclerosis, activated microglia/macrophages appear in active lesions and in normal appearing white matter. However, whether they play a beneficial or a detrimental role in the development of the pathology remains a ...
Tony Valente +4 more
doaj +1 more source
Early MEK1/2 inhibition after global cerebral ischemia in rats reduces brain damage and improves outcome by preventing delayed vasoconstrictor receptor upregulation. [PDF]
PLoS ONE, 2014 BACKGROUND: Global cerebral ischemia following cardiac arrest is associated with increased cerebral vasoconstriction and decreased cerebral blood flow, contributing to delayed neuronal cell death and neurological detriments in affected patients.
Sara Ellinor Johansson +3 more
doaj +1 more source
Function of BID - a molecule of the bcl-2 family - in ischemic cell death in the brain [PDF]
, 2002 Mitochondrial mechanisms, particularly the release of cytochrome c, play a role in the death of nerve and glial cells in cerebral ischemia. We have currently investigated whether BID, a proapoptotic molecule of the bcl-2 family and promoter of the ...
Amin-Hanjani, Sepideh +5 more
core +1 more source
A pilot randomized controlled trial of WeiNaoKang (SaiLuoTong) in treating vascular dementia
AGING MEDICINE, Volume 5, Issue 4, Page 246-256, December 2022., 2022 A 16‐week randomized double‐blind, placebo‐controlled trial for vascular dementia was carried out with WeiNaoKang (or SaiLuoTong). There were significant differences in improvement in cognitive function and activities of daily living, favouring the treatment group.
Junguang Liu +6 more
wiley +1 more source
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 81-90, January 2023., 2023 XELOXIRI neoadjuvant chemotherapy appears to be feasible and efficacious for patients with LARC. Although neoadjuvant XELOXIRI alone did not yield our expected pCR rate, the local recurrence rate, 3‐year DFS and measures of safety met current standards.
Chu Matsuda +16 more
wiley +1 more source
Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia
Journal of Diabetes Research, 2020 Ischemic postconditioning (PC) is proved to efficiently protect diabetic patients with acute myocardial infarction from ischemia-reperfusion injury.
Ling Zhao +5 more
doaj +1 more source
Update on the multimodal pathophysiological dataset of gradual cerebral ischemia in a cohort of juvenile pigs: auditory, sensory and high-frequency sensory evoked potentials [PDF]
, 2021 We expand from a spontaneous to an evoked potentials (EP) data set of brain electrical activities as electrocorticogram (ECoG) and electrothalamogram (EThG) in juvenile pig under various sedation, ischemia and recovery states. This EP data set includes three stimulation paradigms: auditory (AEP, 40 and 2000 Hz), sensory (SEP, left and right maxillary ...
arxiv +1 more source