Early changes in transient adenosine during cerebral ischemia and reperfusion injury. [PDF]
PLoS ONE, 2018 Adenosine is an important neuromodulator in the central nervous system, and tissue adenosine levels increase during ischemic events, attenuating excitotoxic neuronal injury.
Mallikarjunarao Ganesana, B Jill Venton
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microRNA-455-5p alleviates neuroinflammation in cerebral ischemia/reperfusion injury
Neural Regeneration Research, 2022 Neuroinflammation is a major pathophysiological factor that results in the development of brain injury after cerebral ischemia/reperfusion. Downregulation of microRNA (miR)-455-5p after ischemic stroke has been considered a potential biomarker and ...
Jian-Song Zhang +10 more
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Neural Regeneration Research, 2015 The Rho/Rho-kinase signaling pathway plays an important role in cerebral ischemia/reperfusion injury. However, very few studies have examined in detail the changes in the Rho/Rho-kinase signaling pathway in chronic cerebral ischemia.
Ya-yun Yan +7 more
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Variability of the Heart Rhythm as an Additional Marker for Determining Vegetative Functions in Patients with Chronic Cerebral Ischemia [PDF]
, 2018 Aim. Practical cardiology is in constant search for non-invasive vascular risk markers. Heart rhythm reflects the body\u27s response to various stimuli of the external and internal environment. Heart rate variability (HRV) has a prognostic and diagnostic
Inhula, N. (Nataliia)
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Neural Regeneration Research, 2015 Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route.
Seyed Mojtaba Hosseini +4 more
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MicroRNA-670 aggravates cerebral ischemia/reperfusion injury via the Yap pathway
Neural Regeneration Research, 2021 Apoptosis is an important programmed cell death process involved in ischemia/reperfusion injury. MicroRNAs are considered to play an important role in the molecular mechanism underlying the regulation of cerebral ischemia and reperfusion injury. However,
Shi-Jia Yu +4 more
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Barrier mechanisms in neonatal stroke. [PDF]
, 2014 Clinical data continue to reveal that the incidence of perinatal stroke is high, similar to that in the elderly. Perinatal stroke leads to significant morbidity and severe long-term neurological and cognitive deficits, including cerebral palsy ...
Chip, Sophorn +2 more
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Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock. [PDF]
, 2009 The 5-lipoxygenase (5-LO) pathway is responsible for the production of leukotrienes (LTs), inflammatory lipid mediators which play a role in innate immunity. More recently, a pivotal role of LTs in ischemia-reperfusion and shock injury has been suggested.
CUZZOCREA S +2 more
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Neuroprotective Effect of Physical Activity in Ischemic Stroke: Focus on the Neurovascular Unit
Frontiers in Cellular Neuroscience, 2022 Cerebral ischemia is one of the major diseases associated with death or disability among patients. To date, there is a lack of effective treatments, with the exception of thrombolytic therapy that can be administered during the acute phase of ischemic ...
Hui Zhang, Qi Xie, Juan Hu
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Delayed treatment with nimesulide reduces measures of oxidative stress following global ischemic brain injury in gerbils [PDF]
, 2003 Metabolism of arachidonic acid by cyclooxygenase is one of the primary sources of reactive oxygen species in the ischemic brain. Neuronal overexpression of cyclooxygenase-2 has recently been shown to contribute to neurodegeneration following ischemic ...
Alvarez, Dalia +3 more
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