PLoS ONE, 2021 Cerebral ischemia causes tissue death owing to occlusion of the cerebral blood vessels, and cerebral ischemia activates mitogen-activated protein kinase (MAPK) and induces secretion of pro-inflammatory cytokines.
Il-Gyu Ko +7 more
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Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages
Frontiers in Cellular Neuroscience, 2017 In the brain of patients with multiple sclerosis, activated microglia/macrophages appear in active lesions and in normal appearing white matter. However, whether they play a beneficial or a detrimental role in the development of the pathology remains a ...
Tony Valente +4 more
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Early MEK1/2 inhibition after global cerebral ischemia in rats reduces brain damage and improves outcome by preventing delayed vasoconstrictor receptor upregulation. [PDF]
PLoS ONE, 2014 BACKGROUND: Global cerebral ischemia following cardiac arrest is associated with increased cerebral vasoconstriction and decreased cerebral blood flow, contributing to delayed neuronal cell death and neurological detriments in affected patients.
Sara Ellinor Johansson +3 more
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Ischemic Postconditioning Mitigates Retinopathy in Tree Shrews with Diabetic Cerebral Ischemia
Journal of Diabetes Research, 2020 Ischemic postconditioning (PC) is proved to efficiently protect diabetic patients with acute myocardial infarction from ischemia-reperfusion injury.
Ling Zhao +5 more
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Update on the multimodal pathophysiological dataset of gradual cerebral ischemia in a cohort of juvenile pigs: auditory, sensory and high-frequency sensory evoked potentials [PDF]
, 2021 We expand from a spontaneous to an evoked potentials (EP) data set of brain electrical activities as electrocorticogram (ECoG) and electrothalamogram (EThG) in juvenile pig under various sedation, ischemia and recovery states. This EP data set includes three stimulation paradigms: auditory (AEP, 40 and 2000 Hz), sensory (SEP, left and right maxillary ...
arxiv +1 more source
Neural Regeneration Research, 2015 Recent evidence has suggested the neuroprotective effects of physical exercise on cerebral ischemic injury. However, the role of physical exercise in cerebral ischemia-induced hippocampal damage remains controversial.
Nabi Shamsaei +4 more
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Neuroprotective effect of baicalin on focal cerebral ischemia in rats
Neural Regeneration Research, 2018 Baicalin, a flavonoid compound from the root of the herb Scutellaria baicalensis Georgi, has been widely used to treat patients with inflammatory disease.
Jiong Dai +8 more
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Neural Regeneration Research, 2015 The Rho/Rho-kinase signaling pathway plays an important role in cerebral ischemia/reperfusion injury. However, very few studies have examined in detail the changes in the Rho/Rho-kinase signaling pathway in chronic cerebral ischemia.
Ya-yun Yan +7 more
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Early changes in transient adenosine during cerebral ischemia and reperfusion injury. [PDF]
PLoS ONE, 2018 Adenosine is an important neuromodulator in the central nervous system, and tissue adenosine levels increase during ischemic events, attenuating excitotoxic neuronal injury.
Mallikarjunarao Ganesana, B Jill Venton
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microRNA-455-5p alleviates neuroinflammation in cerebral ischemia/reperfusion injury
Neural Regeneration Research, 2022 Neuroinflammation is a major pathophysiological factor that results in the development of brain injury after cerebral ischemia/reperfusion. Downregulation of microRNA (miR)-455-5p after ischemic stroke has been considered a potential biomarker and ...
Jian-Song Zhang +10 more
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