Results 41 to 50 of about 355,372 (304)

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao   +5 more
wiley   +1 more source

Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats [PDF]

open access: yes, 2003
Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury.
Candelario-Jalil, Eduardo   +3 more
core  

Predictors for cerebral edema in acute ischemic stroke treated with intravenous thrombolysis [PDF]

open access: yes, 2017
Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction.
Ahmed, Niaz   +10 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Matrix Metalloproteinases in Cerebral Ischemia [PDF]

open access: yesJournal of Clinical Neurology, 2006
Matrix metalloproteinases (MMPs) are involved in the pathophysiology of several central nervous system diseases that share common pathogeneses, such as disruption of the blood-brain barrier (BBB), neuroinflammation, oxidative stress, and remodeling of the extracellular matrix (ECM). In early ischemic injury, MMPs participate in disruption of the BBB by
Seol-Heui Han, Hahn Young Kim
openaire   +3 more sources

Study of protein expresion [sic] in peri-infarct tissue after cerebral ischemia [PDF]

open access: yes, 2015
In this work, we report our study of protein expression in rat peri-infarct tissue, 48 h after the induction of permanent focal cerebral ischemia. Two proteomic approaches, gel electrophoresis with mass spectrometry and combined fractional diagonal ...
Agulla, Jesús   +9 more
core   +5 more sources

Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun   +9 more
wiley   +1 more source

Potassium channel activators protect the N-methyl-D-aspartate-induced cerebral vascular dilation after combined hypoxia and ischemia in piglets [PDF]

open access: yes, 1998
Background and Purpose-Cerebral arteriolar dilation to N-methyl-D-aspartate (NMDA) is a neuronally mediated multistep process that is sensitive to cerebral hypoxia and ischemia (H/I).
Bari, Ferenc   +2 more
core  

Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri   +6 more
wiley   +1 more source

Therapeutic potential of the renin angiotensin system in ischaemic stroke [PDF]

open access: yes, 2016
The renin angiotensin system (RAS) consists of the systemic hormone system, critically involved in regulation and homeostasis of normal physiological functions [i.e.
Arroja, Mariana Moreira Coutinho   +2 more
core   +1 more source

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