Results 51 to 60 of about 1,244,067 (429)

Variability of the Heart Rhythm as an Additional Marker for Determining Vegetative Functions in Patients with Chronic Cerebral Ischemia [PDF]

, 2018
Aim. Practical cardiology is in constant search for non-invasive vascular risk markers. Heart rhythm reflects the body\u27s response to various stimuli of the external and internal environment. Heart rate variability (HRV) has a prognostic and diagnostic
Inhula, N. (Nataliia)
core   +2 more sources

Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review

Neural Regeneration Research, 2019
To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and considering the inclusion and exclusion criteria of the study. Studies were included
Y. Naderi, Y. Panahi, G. Barreto, Amirhosein Sahebkar   +3 more
semanticscholar   +1 more source

Neuroprotective Mechanisms of Calycosin Against Focal Cerebral Ischemia and Reperfusion Injury in Rats

Cellular Physiology and Biochemistry, 2018
Background/Aims: Emerging evidence suggests that autophagy plays important roles in the pathophysiological processes of cerebral ischemia and reperfusion injury.
Yong Wang, Qianyao Ren, Xing Zhang, Huiling Lu, Jian Chen   +4 more
semanticscholar   +1 more source

Potential application of traditional Chinese medicine in cerebral ischemia—Focusing on ferroptosis

Frontiers in Pharmacology, 2022
Traditional Chinese medicine (TCM) has attracted a great deal of attention in the treatment of cerebral ischemia is credited with the remarkable neuroprotective effects.
Fengyan Zhao, Fengyan Zhao, Fengyan Zhao, Caiwang Peng, Caiwang Peng, Caiwang Peng, Yang Sun, Yang Sun, Yang Sun, Hengli Li, Hengli Li, Hengli Li, Ke Du, Fang Liu, Fang Liu, Fang Liu   +15 more
doaj   +1 more source

CaMKII in cerebral ischemia [PDF]

Acta Pharmacologica Sinica, 2011
Ischemic insults on neurons trigger excessive, pathological glutamate release that causes Ca²⁺ overload resulting in neuronal cell death (excitotoxicity). The Ca²⁺/calmodulin (CaM)-dependent protein kinase II (CaMKII) is a major mediator of physiological excitatory glutamate signals underlying neuronal plasticity and learning. Glutamate stimuli trigger
Andy Hudmon, Nicole M. Ashpole, K. Ulrich Bayer, Rebekah S. Vest, Steven J. Coultrap   +4 more
openaire   +3 more sources

Inhibition of NLRP3 Inflammasome Ameliorates Cerebral Ischemia-Reperfusion Injury in Diabetic Mice

Journal of Neural Transplantation and Plasticity, 2018
Sustained activation of NLRP3 inflammasome is closely related to diabetes and stroke. However, it is unknown whether NLRP3 inflammasome plays an essential role in stroke in diabetes.
Pu Hong, Feng-Xian Li, Ruonan Gu, Ying-ying Fang, Luying Lai, Yong-Wei Wang, Tao Tao, Shi-Yuan Xu, Zhi-Jian You, Hong-Fei Zhang   +9 more
semanticscholar   +1 more source

Neuroprotective effects of ischemic preconditioning on hippocampal CA1 pyramidal neurons through maintaining calbindin D28k immunoreactivity following subsequent transient cerebral ischemia

Neural Regeneration Research, 2017
Ischemic preconditioning elicited by a non-fatal brief occlusion of blood flow has been applied for an experimental therapeutic strategy against a subsequent fatal ischemic insult.
In Hye Kim, Yong Hwan Jeon, Tae-Kyeong Lee, Jeong Hwi Cho, Jae-Chul Lee, Joon Ha Park, Ji Hyeon Ahn, Bich-Na Shin, Yang Hee Kim, Seongkweon Hong, Bing Chun Yan, Moo-Ho Won, Yun Lyul Lee   +12 more
doaj   +1 more source

RTN1-C mediates cerebral ischemia/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways

Cell Death and Disease, 2017
The reticulon family has been found to induce apoptosis, inhibit axon regeneration and regulate protein trafficking. However, little is known about the mechanisms of how reticulon proteins are involved in neuronal death-promoting processes during ...
Lingli Gong, Yuewen Tang, R. An, Muya Lin, Lijian Chen, Jian Du   +5 more
semanticscholar   +1 more source

Hepcidin Is Involved in Iron Regulation in the Ischemic Brain [PDF]

, 2011
Oxidative stress plays an important role in neuronal injuries caused by cerebral ischemia. It is well established that free iron increases significantly during ischemia and is responsible for oxidative damage in the brain.
A Donovan, A Obolensky, AS Zhang, AT McKie, C Peeters-Scholte, C Pigeon, Cai-Zhen Yan, CH Park, Chen-Yang Zhao, D Amantea, D Darshan, D Mu, David I. Finkelstein, DC Lipscomb, DM Wrighting, E Murphy, E Nemeth, E Nemeth, EZ Longa, F Du, FA Sorond, G Nicolas, H Shi, Honglian Shi, HS Aki, Hui Ding, I De Domenico, I De Domenico, J Jia, J Truksa, L Li, L Tacchini, L Viatte, L Yang, LR Hanson, M Bergeron, M Chevion, MV Verga Falzacappa, NJ Mabjeesh, Peng Yu, RM Adibhatla, S Abboud, S Namura, S-M Wang, SE Hamrick, Shi-Yang Chang, SI Chi, SM Wang, T Moos, TA Rouault, Wen-Shuang Wu, WH Tang, WH Tang, Xiang-Lin Duan, Y Chen, Y Ke, Y Mao, Ya-Shuo Zhao, Yan-Zhong Chang, YZ Chang, Z Mao, ZM Qian, ZM Qian   +62 more
core   +3 more sources

Management of delayed cerebral ischemia after subarachnoid hemorrhage

Critical Care, 2016
For patients who survive the initial bleeding event of a ruptured brain aneurysm, delayed cerebral ischemia (DCI) is one of the most important causes of mortality and poor neurological outcome.
Charles L. Francoeur, S. Mayer
semanticscholar   +1 more source