Results 11 to 20 of about 28,910 (233)

Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. [PDF]

, 2009
Cerebral malaria is a life-threatening complication of malaria infection. The pathogenesis of cerebral malaria is poorly defined and progress in understanding the condition is severely hampered by the inability to study in detail, ante-mortem, the ...
KEVIN N. COUPER, Couper, Kevin N, Riley, Eleanor M, Hafalla, Julius CR, Brian De Souza, J., Hafalla, Julius C R, Couper, Kevin N., JULIUS C. R. HAFALLA, de Souza, J Brian, Riley, Eleanor M., ELEANOR M. RILEY, J. BRIAN de SOUZA   +11 more
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Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria [PDF]

, 2009
Background Severe and cerebral malaria are associated with endothelial activation. Angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2) are major regulators of endothelial activation and integrity.
Liles W Conrad, Kain, Kevin C, Kevin C Kain, Kain Kevin C, Liles, W C, Conroy, Andrea L, Conroy Andrea L, Krudsood Srivicha, Erin I Lafferty, Srivicha Krudsood, Lafferty Erin I, Lovegrove, Fiona E, Lafferty, Erin I, Tangpukdee, Noppadon, Fiona E Lovegrove, W Conrad Liles, Tangpukdee Noppadon, Lovegrove Fiona E, Krudsood, Srivicha, Liles, W Conrad, Andrea L Conroy, Noppadon Tangpukdee   +21 more
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Admission Diagnosis of Cerebral Malaria in Adults in an Endemic Area of Tanzania:Implications and Clinical Description [PDF]

, 2003
Cerebralmalariais commonly diagnosed in adults in endemic areas in Africa, both in hospitals and in the community. This presents a paradox inconsistent with the epidemiological understanding that the development of immunity during childhood confers ...
Liyombo, E, Matuja, W, Snow, RW, Makani, J, Snow, R. W, Marsh, K, Warrell, D, Makani, Julie, Marsh, Kevin, Snow, Robert, Warrell, DA   +10 more
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Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. [PDF]

, 2009
BACKGROUND: Limited tools exist to identify which individuals infected with Plasmodium falciparum are at risk of developing serious complications such as cerebral malaria (CM). The objective of this study was to assess serum biomarkers that differentiate
Hawkes, Michael, Nimerta Rajwans, Michael Hawkes, Kevin C Kain, Lafferty, Erin I., John, Chandy C, Sornchai Looareesuwan, Srivicha Krudsood, Tangpukdee, Noppadon, Lafferty, Erin I, Looareesuwan Sornchai, Fiona E Lovegrove, Krudsood, Srivicha, John Chandy C., Rajwans, Nimerta, Opoka, Robert, Noppadon Tangpukdee, Hawkes Michael, Lafferty Erin I., Lovegrove Fiona E., Kain, Kevin C, Looareesuwan, Sornchai, Lovegrove, Fiona E., Opoka Robert O., Krudsood Srivicha, Kain, Kevin C., Erin I Lafferty, Kain Kevin C., Robert O Opoka, Lovegrove, Fiona E, Rajwans Nimerta, John, Chandy C., W Conrad Liles, Liles, W. Conrad, Tangpukdee Noppadon, Liles, W Conrad, Chandy C John, Opoka, Robert O, Liles W. Conrad   +38 more
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Host Blood Gene Signatures Can Detect the Progression to Severe and Cerebral Malaria

Frontiers in Cellular and Infection Microbiology, 2021
Malaria is a major international public health problem that affects millions of patients worldwide especially in sub-Saharan Africa. Although many tests have been developed to diagnose malaria infections, we still lack reliable diagnostic biomarkers for ...
Mohamed Omar, Luigi Marchionni, Georg Häcker, Georg Häcker, Mohamed Tarek Badr, Mohamed Tarek Badr   +5 more
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Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children. [PDF]

, 2010
BACKGROUND: Cerebral malaria (CM) represents a severe outcome of the Plasmodium falciparum infection. Recent genetic studies have correlated human genes with severe malaria susceptibility, but there is little data on genetic variants that increase the ...
Sambo, Maria Rosário, Carla Benchimol, Marques, Maria Isabel, Nuno Sepúlveda, Carlos Penha-Gonçalves, Maria Rosário Sambo, Maria Isabel Marques, Stefan Mustafa, Sepúlveda, Nuno, Sepúlveda Nuno, Gonçalves Lígia, Trovoada, Maria Jesus, Mustafa Stefan, Rute Velosa, Marques Maria Isabel, Velosa, Rute, António Coutinho, Benchimol, Carla, Vatúsia Quinhentos, Sambo Maria Rosário, Quinhentos Vatúsia, Oswald Wagner, Taane G Clark, Benchimol Carla, Penha-Gonçalves Carlos, Penha-Gonçalves, Carlos, Gonçalves, Lígia, Mustafa, Stefan, Coutinho, António, Maria Jesus Trovoada, Coutinho António, Clark Taane G., Lígia Gonçalves, Trovoada Maria Jesus, Quinhentos, Vatúsia, Wagner, Oswald, Wagner Oswald, Taane G. Clark, Clark, Taane G, Velosa Rute   +39 more
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Macrophage migration inhibitory factor is associated with mortality in cerebral malaria patients in India

BMC Research Notes, 2009
Background Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine implicated in the pathogenesis of a number of human diseases including inflammatory neurological diseases.
Udhayakumar Venkatachalam, Dash Aditya P, Stiles Jonathan K, Nagpal Avinash C, McClintock Shannon, Jain Vidhan, Singh Neeru, Lucchi Naomi W   +7 more
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Cerebral Malaria in a Patient with Recent Travel to the Congo Presenting with Delirium: A Case Report

Clinical Practice and Cases in Emergency Medicine, 2020
Introduction: Cerebral malaria, a syndrome of altered consciousness, is a rare and severe neurologic complication resulting from Plasmodium falciparum. 1 Historically, cerebral malaria has been seen more frequently in children rather than adults.
Megan T. Roberson, Austin T. Smith
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Neurotransmitters and molecular chaperones interactions in cerebral malaria: Is there a missing link?

Frontiers in Molecular Biosciences, 2022
Plasmodium falciparum is responsible for the most severe and deadliest human malaria infection. The most serious complication of this infection is cerebral malaria.
Michael Oluwatoyin Daniyan, Funmilola Adesodun Fisusi, Olufunso Bayo Adeoye   +2 more
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Severe malaria - a case of fatal Plasmodium knowlesi infection with post-mortem findings: a case report. [PDF]

, 2010
BACKGROUND: Zoonotic malaria caused by Plasmodium knowlesi is an important, but newly recognized, human pathogen. For the first time, post-mortem findings from a fatal case of knowlesi malaria are reported here.
Hiu, Jessie, Mohammad, Zulkarnaen, Patricia Chandran, Zulkarnaen Mohammad, Adem, P, Paul C Divis, Singh Balbir, Lucas, S.B., Patricia, Adem, Balbir, Singh, Singh, Balbir, Janet Cox-Singh, Singh, B, Balbir Singh, Janet, Cox-Singh, Divis, P.C., Divis Paul C, Kum T, Wong, Chandran, Patricia, Wong Kum T, Paul C, Divis, Sanjeev, Krishna, Wong, Kum T., Zaki, Sherif R., Krishna, S., Chandran Patricia, Kum T Wong, Sanjeev Krishna, Jessie Hiu, Zaki Sherif R, Patricia, Chandran, Singh, B., Sherif R Zaki, Jessie, Hiu, Hiu, J, Chandran, P., Wong, K.T., Wong, KT, Cox-Singh, J, Adem, Patricia, Zulkarnaen, M, Divis, Paul C., Zulkarnaen, Mohammad, Sherif R, Zaki, Lucas Sebastian B, Cox-Singh Janet, Krishna Sanjeev, Mohammad Zulkarnaen, Lucas, Sebastian B., Sebastian B Lucas, Zaki, SR, Cox Singh, Janet, Cox-Singh, J., Krishna, S, Adem Patricia, Chandran, P, Krishna, Sanjeev, Adem, P., Hiu Jessie, Zulkarnaen, M., Patricia Adem, Zaki, S.R., Divis, PC, Lucas, SB, Hiu, J., Sebastian B, Lucas   +65 more
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