Results 41 to 50 of about 1,645,602 (269)

Grading fluorescein angiograms in malarial retinopathy [PDF]

, 2015
This work was funded by The Wellcome Trust (IJCM, SPH, NAVB, MEM, DP, SoL: Grant No. 092668/Z/10/Z; Core Grant No. 084679/Z/08/Z).Background: Malarial retinopathy is an important finding in Plasmodium falciparum cerebral malaria, since it strengthens ...
Malcolm E. Molyneux, Molyneux, Malcolm E, Harding, Simon P, Maude, Richard J., Dhillon, Baljean, Ian J. C. MacCormick, Beare, Nicholas A. V., Beare, Nicholas A V, Simon Glover, Leach, Sophie, Lewallen, Susan, MacCormick, Ian J C, Molyneux, Malcolm E., Nicholas A. V. Beare, David Parry, Sophie Leach, Susan Lewallen, Glover, Simon, Simon P. Harding, MacCormick, Ian JC, Shyamanga Borooah, Borooah, Shyamanga, Harding, Simon P., Richard J. Maude, Parry, David, MacCormick, Ian J. C., Baljean Dhillon, Maude, Richard J, Beare, Nicholas AV, Glover, Simon James   +29 more
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Blood-Brain Barrier in Cerebral Malaria: Pathogenesis and Therapeutic Intervention.

Trends in Parasitology, 2019
Cerebral malaria is a life-threatening complication of malaria caused by the parasite Plasmodium falciparum. The growing problem of drug resistance and the dearth of new antiparasitic drugs are a serious threat to the antimalaria treatment regimes ...
G. Nishanth, D. Schlüter
semanticscholar   +1 more source

Severe falciparum malaria in Gabonese children: clinical and laboratory features. [PDF]

, 2005
BACKGROUND: Malaria continues to claim one to two million lives a year, mainly those of children in sub-Saharan Africa. Reduction in mortality depends, in part, on improving the quality of hospital care, the training of healthcare workers and ...
Mboza, Béatrice, Planche, Timothy, Mboza, B, Jarvis, J, Mboza Béatrice, Eric Kendjo, Kendjo Eric, Arnaud Dzeing-Ella, Mbounja, Monique, Jarvis Joseph, Kombila, Maryvonne, Planche, T, Maryvonne Kombila, Tchoua, R, Tchoua, Rose, Monique Mbounja, Peter G Kremsner, Nze Obiang, PC, Kombila, M, Ngou-Milama Edouard, Planche Timothy, Ulrich Muller-Roemer, Sanjeev Krishna, Ngou-Milama, Edouard, Pascal C Nze Obiang, Kombila Maryvonne, Timothy Planche, Béatrice Mboza, Kendjo, E, Rose Tchoua, Nze Obiang, Pascal C, Dzeing-Ella Arnaud, Kendjo, Eric, Jarvis, Joseph, Nze Obiang Pascal C, Kremsner, Peter G, Muller-Roemer Ulrich, Ngou-Milama, E, Krishna Sanjeev, Tchoua Rose, Muller-Roemer, U, Kremsner, PG, Krishna, S, Edouard Ngou-Milama, Dzeing-Ella, Arnaud, Kremsner Peter G, Krishna, Sanjeev, Mbounja, M, Muller-Roemer, Ulrich, Dzeing-Ella, A, Joseph Jarvis, Mbounja Monique   +51 more
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BIOMOLECULAR ASPECTS AND UPDATE ON TREATMENT OF CEREBRAL MALARIA

Malang Neurology Journal, 2016
Malaria is still becoming a health problem in the world and in Indonesia. Cerebral malaria is one of many features of severe and life threatening malaria. Many hypotheses underlying the pathophysiology of cerebral malaria have been disclosed, but the one
Machlusil Husna, Bowo Hery Prasetyo
doaj   +1 more source

Chorismate synthase mediates cerebral malaria pathogenesis by eliciting salicylic acid-dependent autophagy response in parasite

Biology Open, 2020
Cerebral malaria caused by Plasmodium falciparum is the severest form of the disease resulting in the morbidity of a huge number of people worldwide. Development of effective curatives is essential in order to overcome the fatality of cerebral malaria ...
Malabika Chakrabarti, Deepika Kannan, Akshay Munjal, Hadi Hasan Choudhary, Satish Mishra, Shailja Singh   +5 more
doaj   +1 more source

Desperately seeking therapies for cerebral malaria

Journal of Immunology, 2020
Malaria is a deadly infectious disease caused by parasites of the Plasmodium spp. that takes an estimated 435,000 lives each year, primarily among young African children. For most children, malaria is a febrile illness that resolves with time, but in ∼1%
Brittany A. Riggle, L. Miller, S. Pierce
semanticscholar   +1 more source

Age patterns of severe paediatric malaria and their relationship to Plasmodium falciparum transmission intensity. [PDF]

, 2009
BACKGROUND: The understanding of the epidemiology of severe malaria in African children remains incomplete across the spectrum of Plasmodium falciparum transmission intensities through which communities might expect to transition, as intervention ...
Abdullah Al-Taiar, Idro, Richard, Okiro Emelda A, Berkley, James, Al-Taiar Abdullah, Berkley James A, Berkley, James A, Snow, Robert, Al-Taiar, Abdullah, Berkley, JA, Emelda A Okiro, Okiro, EA, James A Berkley, Snow, Robert W, Okiro, Emelda A, Idro, R, Snow, RW, Robert W Snow, Snow Robert W, Reyburn, H, Hugh Reyburn, Richard Idro, Reyburn Hugh, Al-Taiar, A, Reyburn, Hugh, Idro Richard   +25 more
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Human immunodeficiency virus infection and cerebral malaria in children in Uganda: a case-control study

BMC Pediatrics, 2011
Background Human immunodeficiency virus (HIV)-1 infection increases the burden of malaria by increasing susceptibility to infection and decreasing the response to malarial treatment.
Byarugaba Justus, Musoke Philippa, Imani Peace D, Tumwine James K   +3 more
doaj   +1 more source

CD8+ T cells target cerebrovasculature in children with cerebral malaria.

Journal of Clinical Investigation, 2019
BACKGROUND Cerebral malaria (CM) accounts for nearly 400,000 deaths annually in African children. Current dogma suggests that CM results from infected RBC (iRBC) sequestration in the brain microvasculature and resulting sequelae.
Brittany A. Riggle, Monica Manglani, D. Maric, Kory R. Johnson, Myoung-Hwa Lee, O. Abath, T. Taylor, K. Seydel, A. Nath, L. Miller, D. McGavern, S. Pierce   +11 more
semanticscholar   +1 more source

Cytoadherence and virulence - the case of Plasmodium knowlesi malaria. [PDF]

, 2012
BACKGROUND: Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria.
Cox-Singh, J, Craig, Alister G., Lu Woon, Alister G Craig, Farrah A Fatih, Woon, Lu Chan, Siner, Angela, Singh Balbir, Cox-Singh, Janet, Siner Angela, Fatih, FA, Singh, Balbir, Janet Cox-Singh, Singh, B, Balbir Singh, Fatih, Farrah A., Cox-Singh Janet, Krishna Sanjeev, Ahmed, Atique, Siner, A, Angela Siner, Cox Singh, Janet, Ahmed Atique, Craig Alister G, Woon, LC, Woon Lu, Krishna, S, Fatih Farrah A, Sanjeev Krishna, Craig, AG, Krishna, Sanjeev, Ahmed, A, Craig, Alister, Atique Ahmed, Lu Chan Woon, Balbir, Singh, Craig, Alister G, Lu, Chan Woon, Sanjeev, Krishna, Cox-Singh, J., Atique M, Ahmed, Farrah, A Fatih   +41 more
core   +1 more source