BIOMOLECULAR ASPECTS AND UPDATE ON TREATMENT OF CEREBRAL MALARIA
Malaria is still becoming a health problem in the world and in Indonesia. Cerebral malaria is one of many features of severe and life threatening malaria. Many hypotheses underlying the pathophysiology of cerebral malaria have been disclosed, but the one
Machlusil Husna, Bowo Hery Prasetyo
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Reorganization of host red blood cells by the malaria parasite Plasmodium falciparum enables their sequestration via attachment to the microvasculature.
Oscar Bate Akide Ndunge +2 more
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A case report of pitfall of fever and altered mental status: cerebral malaria due to in an adult traveler returning from Congo [PDF]
Background Cerebral malaria, caused by Plasmodium falciparum, can lead to severe neurological complications. It is more frequently observed in children than in adults.
Soo-Hyun Park +4 more
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Natural regulatory (CD4+CD25+FOXP+) T cells control the production of pro-inflammatory cytokines during Plasmodium chabaudi adami infection and do not contribute to immune evasion. [PDF]
Different functions have been attributed to natural regulatory CD4+CD25+FOXP+ (Treg) cells during malaria infection. Herein, we assessed the role for Treg cells during infections with lethal (DS) and non-lethal (DK) Plasmodium chabaudi adami parasites ...
Belanger, B +4 more
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Background Human immunodeficiency virus (HIV)-1 infection increases the burden of malaria by increasing susceptibility to infection and decreasing the response to malarial treatment.
Byarugaba Justus +3 more
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Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care. [PDF]
BACKGROUND\ud \ud An effective malaria vaccine, deployed in conjunction with other malaria interventions, is likely to substantially reduce the malaria burden. Efficacy against severe malaria will be a key driver for decisions on implementation.
Amanda Leach +18 more
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A rare case of young stroke in 16 years old female with Plasmodium vivax malaria infection
Malaria is the most important parasitic disease in the world, in terms of both prevalence and mortality. Infection rate is high due to raise of strains resistant to the antimalarial medicines & social factors.
N U Gediya +3 more
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Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model [PDF]
International audienceBackgroundProveblue®, a methylene blue dye that complies with European Pharmacopoeia and contains limited organic impurities and heavy metals of recognized toxicity, showed in vitro synergy against Plasmodium falciparum when ...
Briolant, Sébastien +3 more
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Imaging features of fulminant cerebral malaria: A case report
Cerebral malaria is associated with high mortality and morbidity in patients infected with Plasmodium Falciparum. The mechanisms of cerebral malaria include sequestration of parasitized red blood cells in brain capillaries, production of cytokines ...
Ahmed El Beltagi +4 more
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Cytoadherence and virulence - the case of Plasmodium knowlesi malaria. [PDF]
BACKGROUND: Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria.
Ahmed, A +7 more
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