Single molecule and multiple bond characterization of catch bond associated cytoadhesion in malaria [PDF]
The adhesion of malaria infected red blood cells (iRBCs) to host endothelial receptors in the microvasculature, or cytoadhesion, is associated with severe disease pathology such as multiple organ failure and cerebral malaria.
Cao, Jianshu +3 more
core +1 more source
This review introduces the concept of “general curvy surface reconstruction,” which incorporates both geometric and physical dimensions, representing an upgrade over conventional geometric reconstruction that focuses solely on spatial relationships. Particular emphasis is placed on the emerging opportunities enabled by advanced measurement techniques ...
Chen Shang +8 more
wiley +1 more source
Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare +7 more
wiley +1 more source
Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers. [PDF]
The mechanisms underlying the heterogeneity of clinical malaria remain largely unknown. We hypothesized that differential gene expression contributes to phenotypic variation of parasites which results in a specific interaction with the host, leading to ...
Talleh Almelli +13 more
doaj +1 more source
Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly +14 more
doaj +1 more source
Throat and rectal swabs may have an important role in MRSA screening of critically ill patients.
OBJECTIVE: Methicillin-resistant Staphylococcus aureus (MRSA) is a major problem in intensive care units (ICU). International guidelines recommend screening patients for MRSA on admission, although consensus on sites required for optimum detection has ...
Batra, Rahul +3 more
core +1 more source
Cytoadherence in paediatric malaria: ABO blood group, CD36, and ICAM1 expression and severe Plasmodium falciparum infection [PDF]
As a leading cause of childhood mortality worldwide, selection pressure by Plasmodium falciparum continues to shape the human genome. Severe disturbances within the microcirculation result from the adhesion of infected erythrocytes to host receptors on ...
Cserti-Gazdewich, Christine M +8 more
core +2 more sources
The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu +2 more
wiley +1 more source
Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets [PDF]
© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.
Antwi-Baffour, Samuel +5 more
core +5 more sources
Imaging malaria parasites across scales and time
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley +1 more source

