Results 61 to 70 of about 23,120 (223)

Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice. [PDF]

PLoS ONE, 2017
A devastating complication of Plasmodium falciparum infection is cerebral malaria, in which vascular leakage and cerebral swelling lead to coma and often death. P. falciparum produces a protein called histidine-rich protein II (HRPII) that accumulates to
Priya Pal, Amanda E Balaban, Michael S Diamond, Photini Sinnis, Robyn S Klein, Daniel E Goldberg   +5 more
doaj   +1 more source

Methylene Blue-Based Combination Therapy with Amodiaquine Prevents Severe Malaria in an Experimental Rodent Model

Pharmaceutics, 2022
Untreated malaria can progress rapidly to severe forms (
Jérôme Dormoi, Rémy Amalvict, Mathieu Gendrot, Bruno Pradines   +3 more
doaj   +1 more source

Risk factors associated with progression from pre‐eclampsia to eclampsia: A prospective cohort study and population‐wide data analysis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Younger maternal age and lower socioeconomic status emerged as key risk factors for progression from pre‐eclampsia to eclampsia in two low‐ and middle‐income countries (Uganda and Ecuador), challenging the traditional focus on disease severity alone. This suggests a need to broaden risk assessment criteria.
Annettee Nakimuli, Brittany A. Jasper, Sarah Nakubulwa, Moses Adroma, Jackline Akello, Imelda Namagembe, Musa Sekikubo, Eve Nakabembe, Ashley Moffett, Catherine E. Aiken   +9 more
wiley   +1 more source

Increased Survival in B-Cell-Deficient Mice during Experimental Cerebral Malaria Suggests a Role for Circulating Immune Complexes

mBio, 2014
The pathogenesis of malaria, an insect-borne disease that takes millions of lives every year, is still not fully understood. Complement receptor 1 (CR1) has been described as a receptor for Plasmodium falciparum, which causes cerebral malaria in humans ...
Rosane B. de Oliveira, Jennifer P. Wang, Sanjay Ram, Ricardo T. Gazzinelli, Robert W. Finberg, Douglas T. Golenbock   +5 more
doaj   +1 more source

Imaging malaria parasites across scales and time

Journal of Microscopy, EarlyView.
Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley   +1 more source

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, EarlyView.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Causal effect of severe and non‐severe malaria on dyslipidemia in African Ancestry individuals: A Mendelian randomization study

Annals of Human Genetics, Volume 89, Issue 4, Page 178-187, July 2025.
Abstract Background Dyslipidemia is becoming prevalent in Africa, where malaria is endemic. Observational studies have documented the long‐term protective effect of malaria on dyslipidemia; however, these study designs are prone to confounding. Therefore, we used Mendelian randomization (MR, a method robust to confounders and reverse causation) to ...
Mariam Traore, Harouna Sangare, Oudou Diabate, Abdoulaye Diawara, Cheickna Cissé, Oyekanmi Nashiru, Jian Li, Jeffrey Shaffer, Mamadou Wélé, Seydou Doumbia, Tinashe Chikowore, Opeyemi Soremekun, Segun Fatumo   +12 more
wiley   +1 more source

The contribution of extracellular RNA and its derived biomaterials in disease management

BMEMat, Volume 3, Issue 2, June 2025.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei, Zhangyi Wang, Zixuan Qin, Qianqian Wan, Yutao Li, Franklin R. Tay, Chenyu Wang, Tong Zhang, Lina Niu   +8 more
wiley   +1 more source

Human cerebral malaria and Plasmodium falciparum genotypes in Malawi

Malaria Journal, 2012
Background Cerebral malaria, a severe form of Plasmodium falciparum infection, is an important cause of mortality in sub-Saharan African children.
Milner Danny A, Vareta Jimmy, Valim Clarissa, Montgomery Jacqui, Daniels Rachel F, Volkman Sarah K, Neafsey Daniel E, Park Daniel J, Schaffner Stephen F, Mahesh Nira C, Barnes Kayla G, Rosen David M, Lukens Amanda K, Van-Tyne Daria, Wiegand Roger C, Sabeti Pardis C, Seydel Karl B, Glover Simon J, Kamiza Steve, Molyneux Malcolm E, Taylor Terrie E, Wirth Dyann F   +21 more
doaj   +1 more source

Epidemiological, clinical and therapeutic aspects of cerebral malaria imported in Albania

Journal of Infection in Developing Countries, 2016
This is a case-report of two patients with cerebral malaria (CM) imported from West-African countries. Notably, this form of malaria was developed as a second disease episode, while the first episode was experienced in West Africa. These findings suggest
Arben Ndreu, Diana Hajdari, Anduena Ndoni, Klodiana Shkurti, Dhimiter Kraja, Najada Como, Silva Bino, Nevila Gjermeni, Rudin Domi, Ervin C Mingomataj   +9 more
doaj   +1 more source