Results 71 to 80 of about 23,120 (223)
The Case for the Use of PPARγ Agonists as an Adjunctive Therapy for Cerebral Malaria
PPAR Research, 2012 Cerebral malaria is a severe complication of Plasmodium falciparum infection associated with high mortality even when highly effective antiparasitic therapy is used.
Lena Serghides
doaj +1 more source
Imaging features of fulminant cerebral malaria: A case report
Radiology Case Reports, 2023 Cerebral malaria is associated with high mortality and morbidity in patients infected with Plasmodium Falciparum. The mechanisms of cerebral malaria include sequestration of parasitized red blood cells in brain capillaries, production of cytokines ...
Ahmed El Beltagi +4 more
doaj
Murine malaria is associated with significant hearing impairment
Malaria Journal, 2010 Background Plasmodium falciparum malaria has been suspected to cause hearing loss. Developmental, cognitive and language disorders have been observed in children, surviving cerebral malaria.
Stephan Kurt +10 more
doaj +1 more source
EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria.
PLoS Pathogens, 2020 Disruption of blood-brain barrier (BBB) function is a key feature of cerebral malaria. Increased barrier permeability occurs due to disassembly of tight and adherens junctions between endothelial cells, yet the mechanisms governing junction disassembly ...
Thayer K Darling +9 more
doaj +1 more source
Nature CommunicationsFactors governing the clinical trajectory of Plasmodium falciparum infection remain an important area of investigation. Here we present transcriptomic, proteomic and metabolomic analyses comparing clinical subtypes of severe Plasmodium falciparum malaria
Rafal S. Sobota +32 more
doaj +1 more source
Pathogenesis of Cerebral Malaria: New Diagnostic Tools, Biomarkers and Therapeutic Approaches
Frontiers in Cellular and Infection Microbiology, 2015 Cerebral malaria is a severe neuropathological complication of Plasmodium falciparum infection. It results in high mortality and post-recovery neuro-cognitive disorders in children, even after appropriate treatment with effective anti-parasitic drugs ...
Praveen Kishore Sahu +6 more
doaj +1 more source
Journal of Obstetrics and Gynaecology, 2006 Each year approximately 300 million people are affected by malaria with over 1 million deaths in Africa Asia Oceania and South America attributable to malaria. Malaria is the most important of the parasitic diseases of human beings especially for those people living in sub-Saharan Africa where about 90%of deaths from malaria occur.
A. L. Akinwuntan +2 more
openaire +3 more sources