Results 71 to 80 of about 58,585 (250)

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song, Yu Wei, Peng Jia, Shan He, Qian Wang, Manman Xu, Hongzhi Liu, Pengtao Bao, Shanyue Guan, Xiaozhong Qu   +9 more
wiley   +1 more source

Hemiparesis post cerebral malaria

The Pan African Medical Journal, 2015
Cerebral malaria is one of the most serious complications in the Plasmodium falciparum infection. In endemic areas, the cerebral malaria interested mainly children.
Oumkaltoum Taiaa, Touriya Amil, Abdelatif Darbi   +2 more
doaj   +1 more source

Plasmodium falciparum histidine-rich protein II causes vascular leakage and exacerbates experimental cerebral malaria in mice. [PDF]

PLoS ONE, 2017
A devastating complication of Plasmodium falciparum infection is cerebral malaria, in which vascular leakage and cerebral swelling lead to coma and often death. P. falciparum produces a protein called histidine-rich protein II (HRPII) that accumulates to
Priya Pal, Amanda E Balaban, Michael S Diamond, Photini Sinnis, Robyn S Klein, Daniel E Goldberg   +5 more
doaj   +1 more source

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study [PDF]

, 2018
Background: Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms—many related to the structure or function of red blood cells—and risk for severe Plasmodium falciparum ...
Alexander, W Macharia, Anna, Jeffreys, Bancone, G., Benjamin, Tsofa, Carolyne, M Ndila, Christina, Hubbart, Dominic, P Kwiatkowski, Gavin, Band, Geraldine, Clarke, Gideon, Nyutu, Hughes, C., John, Ojal, Kate, Rowlands, Kathryn, Maitland, Kennedy, O Awuondo, Kevin, Marsh, Kirk, A Rockett, Malariagen, Consortium, Mangano, V., Margaret, Mackinnon, Modiano, David, Mohammed, Shebe, Neema, Mturi, Norbert, Peshu, Nuno, Sepúlveda, Silvia, Kariuki, Sophie, Uyoga, Taane, G Clark, Thomas, N Williams   +28 more
core   +1 more source

Prevalence and factors associated with cerebral malaria among children aged 6 to 59 months with severe malaria in Western Uganda: a hospital-based cross-sectional study

BMC Pediatrics
Introduction Cerebral malaria, caused by Plasmodium falciparum, represents the most severe neurologic complication of malaria. Its association with high morbidity and mortality rates, especially among young children, underscores its clinical significance.
Banga Mseza, Patrick Kumbakulu Kumbowi, Martin Nduwimana, Desire Banga, Emmanuel Tibasima Busha, Walufu Ivan Egesa, Richard Justin Odong, Grace Ndeezi   +7 more
doaj   +1 more source

Unveiling new perspectives about the onset of neurological and cognitive deficits in cerebral malaria: exploring cellular and neurochemical mechanisms

Frontiers in Cellular and Infection Microbiology
Cerebral malaria is the most severe and lethal complication caused by Plasmodium falciparum infection, leading to critical neurological impairments and long-term cognitive, behavioral, and neurological sequelae in survivors, particularly affecting ...
Renato M. S. de Lima, Luana K. R. Leão, Luana C. Martins, Adelaide da C. Fonseca Passos, Evander de J. Oliveira Batista, Anderson M. Herculano, Karen R. H. M. Oliveira   +6 more
doaj   +1 more source

Characteristic abnormalities in cerebrospinal fluid biochemistry in children with cerebral malaria compared to viral encephalitis

Cerebrospinal Fluid Research, 2006
Background In developing countries where Plasmodium falciparum malaria is endemic, viral encephalitis and cerebral malaria are found in the same population, and parasitemia with Plasmodium falciparum is common in asymptomatic children.
Atmakuri RM, Veena S, Jakka SR, Eisenhut M   +3 more
doaj   +1 more source

Randomized, Controlled Trial of the Long Term Safety, Immunogenicity and Efficacy of RTS,S/AS02(D) Malaria Vaccine in Infants Living in a Malaria-Endemic Region. [PDF]

, 2013
The RTS,S/AS malaria candidate vaccine is being developed with the intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) of the World Health Organization.
A Olotu, Ali Mohammed, Amanda Leach, B Lell, David Schellenberg, E Macete, EV Macete, Francisca Machera, Grace Mwangoka, Hassan Mshinda, J Sacarlal, J Sacarlal, JJ Aponte, Joe Cohen, Johan Vekemans, KA Bojang, KE Kester, KP Asante, Marc Lievens, Marcel Tanner, Marie-Claude Dubois, MedDRA, MT White, Mwanajaa Shomari, Nahya Salim, Omar Juma, P Aide, P Aide, P Bejon, Richard Kamata, S Abdulla, S Owusu-Agyei, Salim Abdulla, ST Agnandji, ST Agnandji, ST Agnandji, Sulende Kubhoja, Terrell Carter, Thomas Aebi, Tonya Villafana, W Ripley Ballou, WHO, WHO, WHO/IVR   +43 more
core   +5 more sources

Explosive Weapons Trauma Care Collective (EXTRACCT) Clinical Practice Guideline: Resuscitation of Pediatric Blast Injury Patient

World Journal of Surgery, Volume 50, Issue 1, Page 162-176, January 2026.
Children living in conflict or post‐conflict zones are frequently exposed to explosive injuries, with thousands killed and injured every year. The clinical practice guideline from the Explosive Weapons Trauma Care Collective (EXTRACCT) group provides a review of current best practice for the resuscitation of a child who has sustained a blast injury in ...
Gavin Wooldridge, Francis Abantanga, Emmanuel Ameh, Vinay N. Kampalath, Paul Reavley, Philip C. Spinella, On behalf of the EXTRACCT Clinical Practice Guidelines Collaboration   +6 more
wiley   +1 more source

STATUS HEMATOLOGI PENDERITA MALARIA SEREBRAL

Majalah Kedokteran Andalas, 2009
AbstrakMalaria masih merupakan masalah kesehatan masyarakat dunia. Berdasarkan klasifikasi klinis, malaria dibedakan atas malaria berat dan malaria tanpa komplikasi.
Nurhayati Nurhayati
doaj   +1 more source