Results 151 to 160 of about 8,233,957 (244)

Associations of intracranial arterial stenosis and cerebral small vessel diseases with acute ischemic lesions in spontaneous intracerebral hemorrhage. [PDF]

Front Neurol
Hou Y, Yang S, Li Y, Hu W, Yang L.
europepmc   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Meningeal lymphatic dysfunction in sporadic cerebral small vessel diseases and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy by DCE-MRI. [PDF]

Quant Imaging Med Surg
Wang H, Ren X, Shen Y, Qiu Y, Li M, Luo S, Zhang Z, Wu L, Zhou M, Jiang Y, Zhou F, Hong D.   +11 more
europepmc   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

Biotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga, Udisha Singh, Sachin Dattram Pawar   +2 more
wiley   +1 more source

Research Advancements on the Correlation Between Spontaneous Intracerebral Hemorrhage of Different Etiologies and Imaging Markers of Cerebral Small Vessel Disease

Neuropsychiatric Disease and Treatment
Yu-Tong Liu,1 Chun-Yan Lei,1 Lian-Mei Zhong2 1Department of Neurology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, People’s Republic of China; 2Department of Neurology, Xuanwu Hospital of Capital Medical ...
Liu YT, Lei CY, Zhong LM
doaj  

Heterogeneous blood-brain barrier dysfunction in cerebral small vessel diseases. [PDF]

Alzheimers Dement
Ying Y, Li Y, Yao T, Shao X, Tang W, Montagne A, Chabriat H, Wang DJJ, Wang C, Yang Q, Cheng X.   +10 more
europepmc   +1 more source

Blood Pressure Variability and Cerebral Small Vessel Disease: a Systematic Review, Meta-Analysis and Meta-Regression

, 2019
Blood Pressure Variability and Cerebral Small Vessel Disease: a Systematic Review, Meta-Analysis and Meta ...
P Tully (20672519)
core  

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Intra-cisterna-magna bevacizumab injection (ICM-BI) reproduces pathological alterations of cerebral small vessel diseases. [PDF]

J Cereb Blood Flow Metab
Kang X, Su X, Li T, Wang S, Huang H, Liu Y, Li C, Deng X, Hu M, Lu T, Wei L, Cai W, Lu Z.   +12 more
europepmc   +1 more source