Characterize the non-Gaussian diffusion property of cerebrospinal fluid using Diffusion Kurtosis Imaging and explore its diagnostic efficacy for Alzheimer's disease [PDF]
arXiv, 2023 Differentiating Alzheimer's disease (AD) patients from healthy controls (HCs) remains a challenge. The changes of protein level in cerebrospinal fluid (CSF) of AD patients have been reported in the literature. Macromolecules will hinder the movement of water in CSF and lead to non-Gaussian diffusion.
arxiv
Cerebrospinal fluid protein carbonylation identifies oxidative damage in autoimmune demyelination [PDF]
, 2016 Oxidative damage occurs in multiple sclerosis, but is difficult to identify antemortem and remains an unknown contributor to disease progression. Carbonylation is a quantitative measure of protein oxidation.
Berlett +17 more
core +1 more source
Tracking Tumor Evolution in Glioma through Liquid Biopsies of Cerebrospinal Fluid
Nature, 2018 Diffuse gliomas are the most common malignant brain tumours in adults and include glioblastomas and World Health Organization (WHO) grade II and grade III tumours (sometimes referred to as lower-grade gliomas).
Alexandra M Miller +29 more
semanticscholar +1 more source
A Case of Cerebrospinal Fluid Rhinorrhoea: A Surgical Challenge [PDF]
Journal of Clinical and Diagnostic Research, 2013 CEREBROSPINAL FLUID rhinorrhoea is defined as the leakage of CEREBROSPINAL FLUID through the nose due to communication between nasal cavity and Sub–arachnoid space. It occurs due to breach in 4 layers–mucosa of the nose and PNS, skull base, Duramater,
Sumitha R +3 more
doaj +1 more source
Antibiotics, 2022 Infection of a cerebrospinal fluid system is a serious medical complication. We performed a retrospective monocentric analysis on temporary and permanent cerebrospinal fluid devices in children with and without cancer, covering a period of over 14 years.
Antonia Diederichs +8 more
doaj +1 more source
Alzheimer Disease Detection from Raman Spectroscopy of the Cerebrospinal Fluid via Topological Machine Learning [PDF]
arXiv, 2023 The cerebrospinal fluid (CSF) of 19 subjects who received a clinical diagnosis of Alzheimer's disease (AD) as well as of 5 pathological controls have been collected and analysed by Raman spectroscopy (RS). We investigated whether the raw and preprocessed Raman spectra could be used to distinguish AD from controls.
arxiv
Review of "The Blood-Cerebrospinal Fluid Barrier" by Wei Zheng and Adam Chodobski (editors) [PDF]
, 2006 This multi-author volume on the blood-cerebrospinal fluid barrier summarizes past and current research in the areas of choroid plexus and cerebrospinal fluid in health and ...
H Davson, H Davson, Hazel C Jones
core +3 more sources
bioRxiv, 2018 Metagenomic next-generation sequencing (mNGS) for pan-pathogen detection has been successfully tested in proof-of-concept case studies in patients with acute illness of unknown etiology, but to date has been largely confined to research settings. Here we
Steve Miller +17 more
semanticscholar +1 more source
Application of MGMT Promoter Methylation of Cerebrospinal Fluid in Diagnosis of Glioma
Zhongliu Fangzhi Yanjiu, 2018 Objective To compare the sensitivity and specificity of O6-methylguanine-DNA methyltransferase(MGMT) promoter methylation between peripheral blood and cerebrospinal fluid in the initial diagnosis of glioma patients. Methods We collected the tumor tissues,
WANG Long +6 more
doaj +1 more source
Primary cerebrospinal fluid leak complicated with meningitis and parainfectious vasculitis: case report and literature review [PDF]
, 2020 This paper aims to describe a case of an immunocompetent 60-year-old patient presenting a subarachnoid hemorrhage in the absence of aneurysmal disease.
Cariello, Raíssa Habka +3 more
core +2 more sources