Results 71 to 80 of about 562,738 (359)

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Deciphering the impact of cerebrospinal fluid on stem cell fate as a new mechanism to enhance clinical therapy development

Frontiers in Neuroscience
Neural stem cells (NSCs) hold a very significant promise as candidates for cell therapy due to their robust neuroprotective and regenerative properties. Preclinical studies using NSCs have shown enough encouraging results to perform deeper investigations
Klaudia Radoszkiewicz, Aleksandra Bzinkowska, Magdalena Chodkowska, Paulina Rybkowska, Monika Sypecka, Ilona Zembrzuska-Kaska, Anna Sarnowska   +6 more
doaj   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

Method of making an ion beam sputter-etched ventricular catheter for hydrocephalus shunt [PDF]

, 1984
The centricular catheter comprises a multiplicity of inlet microtubules. Each microtubule has both a large opening at its inlet end and a multiplicity of microscopic openings along its lateral surfaces.
Banks, B. A.
core   +1 more source

Cerebrospinal fluid biomarkers in the Longitudinal Early‐onset Alzheimer's Disease Study [PDF]

, 2023
Jeffrey L. Dage, Ani Eloyan, Maryanne Thangarajah, Dustin B. Hammers, Anne M. Fagan, Julia Gray, Suzanne E. Schindler, Casey Snoddy, Kelly Nudelman, Kelley Faber, Tatiana M. Foroud, Paul Aisen, Percy Griffin, Lea T. Grinberg, Leonardo Iaccarino, Kala Kirby, Joel H. Kramer, Robert A. Koeppe, Walter A. Kukull, Renaud La Joie, Nidhi S. Mundada, Melissa E. Murray, Malia Rumbaugh, David N. Soleimani‐Meigooni, Arthur W. Toga, Alexandra Touroutoglou, Prashanthi Vemuri, Alireza Atri, Laurel Beckett, Gregory S. Day, Neill R. Graff‐Radford, Ranjan Duara, Lawrence S. Honig, David T. Jones, Joseph C. Masdeu, Mario F. Mendez, Erik S. Musiek, Chiadi U. Onyike, Meghan Riddle, Emily Rogalskı, Stephen Salloway, Sharon J. Sha, Raymond Scott Turner, Thomas S. Wingo, David A. Wolk, Kyle Womack, María C. Carrillo, Bradford C. Dickerson, Gil D. Rabinovici, Liana G. Apostolova   +49 more
openalex   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu, Oliver Robinson, Christina M. Lill, Anna Matton, Raquel Puerta, Pilar Sanz, Merce Boada, Agustín Ruiz, Lefkos Middleton, for the Alzheimer's Disease Neuroimaging Initiative   +9 more
wiley   +1 more source

The chaperone protein clusterin may serve as a cerebrospinal fluid biomarker for chronic spinal cord disorders in the dog [PDF]

, 2014
Chronic spinal cord dysfunction occurs in dogs as a consequence of diverse aetiologies, including long-standing spinal cord compression and insidious neurodegenerative conditions. One such neurodegenerative condition is canine degenerative myelopathy (DM)
A Brodbelt, A Felbecker, AM Lidstrom, AM Lidstrom, AM Nilselid, B Szoor, C Sihlbom, C Wang, DR Averill, EM Schrijvers, FA Wininger, GB Cherubini, GD Shelton, H Reiber, H Satoh, H Tumani, Intan N. F. Shafie, IR Griffiths, Jacques Penderis, JR Coates, JW Harvey, K Al-Saktawi, K Sasaki, L Klimaschewski, M Calero, MA Stoodley, Mark McLaughlin, Mary Ann A. Lim, O Cordero-Llana, P Montague, P Narayan, PA March, Pamela E. J. Johnston, Paul Montague, PEJ Johnston, Richard Burchmore, RP Grewal, SE Jones, T Awano, Thomas J. Anderson   +39 more
core   +1 more source

Diagnostic value of the cerebrospinal fluid lipoarabinomannan assay for tuberculous meningitis: a systematic review and meta-analysis [PDF]

, 2023
Yali Chen, Mengmeng Zhu, Cuiping Guan, Yanan Zhang, Mao-Shui Wang   +4 more
openalex   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source