Results 71 to 80 of about 2,571,762 (365)

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases

Fluids and Barriers of the CNS, 2019
The fine balance between the secretion, composition, volume and turnover of cerebrospinal fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance can be disrupted.
S. Bothwell, D. Janigro, A. Patabendige
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Cerebrospinal fluid

Definitions, 2019
Cerebrospinal fluid is a highly specialised fluid that plays a key role in maintaining the health of the central nervous system. While collection is not without risk, the evaluation of this fluid can aid in diagnosing a variety of neurological conditions
Emily M. Hooper
semanticscholar   +1 more source

Ion beam sputter-etched ventricular catheter for hydrocephalus shunt [PDF]

, 1983
A cerebrospinal fluid shunt in the form of a ventricular catheter for controlling the condition of hydrocephalus by relieving the excessive cerebrospinal fluid pressure is described.
Banks, B. A.
core   +1 more source

Association of Altered Liver Enzymes With Alzheimer Disease Diagnosis, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid Biomarkers

JAMA Network Open, 2019
Key Points Question Are liver function markers associated with cognition and the “A/T/N” (amyloid, tau, and neurodegeneration) biomarkers for Alzheimer disease?
K. Nho, Alexandra Kueider-Paisley, S. Ahmad, Siamak Mahmoudiandehkordi, M. Arnold, S. Risacher, Gregory Louie, Colette Blach, R. Baillie, Xianlin Han, G. Kastenmüller, J. Trojanowski, L. Shaw, M. Weiner, P. Doraiswamy, C. M. Duijn, C. Duijn, A. Saykin, R. Kaddurah-Daouk   +18 more
semanticscholar   +1 more source

Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease

Acta Neuropathologica, 2018
The barrier between the blood and the ventricular cerebrospinal fluid (CSF) is located at the choroid plexuses. At the interface between two circulating fluids, these richly vascularized veil-like structures display a peculiar morphology explained by ...
J. Ghersi-Egea, N. Strazielle, M. Catala, V. Silva-Vargas, Fiona Doetsch, B. Engelhardt   +5 more
semanticscholar   +1 more source

Top-cited articles in cerebrospinal fluid leak (rhinorrhea and otorrhea) (1945–2018)

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: As scientific knowledge has grown in biomedicine, it has also become necessary to develop tools to manage and understand the body of evidence.
Irene Monjas-Cánovas, Isabel Belinchón-Romero, Juan-Ramón Gras-Albert, Gregorio González-Alcaide, José Manuel Ramos-Rincón   +4 more
doaj  

Blood–brain and blood–cerebrospinal fluid barrier permeability in spontaneously hypertensive rats

Fluids and Barriers of the CNS, 2018
Background Hypertension is an important risk factor for cerebrovascular disease, including stroke and dementia. Both in humans and animal models of hypertension, neuropathological features such as brain atrophy and oedema have been reported.
Daphne M. P. Naessens, Judith de Vos, Ed VanBavel, Erik N. T. P. Bakker   +3 more
doaj   +1 more source

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

Acta Neuropathologica Communications, 2018
The diagnosis and treatment of synucleinopathies such as Parkinson disease and dementia with Lewy bodies would be aided by the availability of assays for the pathogenic disease-associated forms of α-synuclein (αSynD) that are sufficiently sensitive ...
B. Groveman, C. Orrú, A. Hughson, L. Raymond, G. Zanusso, B. Ghetti, Katrina J Campbell, J. Safar, D. Galasko, B. Caughey   +9 more
semanticscholar   +1 more source

What does an isolated cerebrospinal fluid band mean: a tertiary centre experience

Aktualności Neurologiczne, 2015
Introduction: The presence of oligoclonal bands in cerebrospinal fluid of multiple sclerosis patients is now well established to support the clinical diagnosis. On the other hand, a single band response can represent the initial stage of an oligoclonal
Turan Poyraz, Derya Kaya, Egemen Idiman, Nuri Karabay, Duygu Arslan, Yasemin Karakaptan   +5 more
doaj   +1 more source