Results 91 to 100 of about 68,629 (274)

Uncovering the ceRNA Network Related to the Prognosis of Stomach Adenocarcinoma Among 898 Patient Samples

Biochemical Genetics
Stomach adenocarcinoma (STAD) patients are often associated with significantly high mortality rates and poor prognoses worldwide. Among STAD patients, competing endogenous RNAs (ceRNAs) play key roles in regulating one another at the post-transcriptional
Zhe Liu, Fang Liu, O. O. Petinrin, Fuzhou Wang, Yu Zhang, Ka-Chun Wong   +5 more
semanticscholar   +1 more source

LINC01605 Predicts the Poor Prognosis of Non‐Small Cell Lung Cancer and Promotes Chemotherapy Resistance by Regulating miR‐7111‐5p/ELK1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Non‐small cell lung cancer (NSCLC) is characterized by high incidence, mortality, and poor patient prognosis, with chemotherapy resistance being a common challenge. This research intends to identify key molecules involved in NSCLC and elucidate the regulatory role of the LINC01605/miR‐7111‐5p/ELK1 axis in chemotherapy resistance. LINC01605 and
Fang Zhang, Zhi‐Liang Yang, Tian‐Tian Qin, Guo‐Jun Zhang, Xiang Li   +4 more
wiley   +1 more source

LncRNA MIR155HG functions as a ceRNA for inhibition of lung adenocarcinoma growth and prediction of prognosis

, 2021
Introduction Long non-coding RNAs (lncRNAs) functioning as competing endogenous RNAs (ceRNAs) play critical roles in tumour progression. However, prognosis-related ceRNA networks in lung adenocarcinoma (LUAD) have not been well characterised.
Jing Wang, Jie Li, Li, Jie, Wang, Jing
core   +1 more source

Integrated Analysis of lncRNA–Mediated ceRNA Network in Lung Adenocarcinoma

Frontiers in Oncology, 2020
Background A growing body of evidence indicates that long non-coding RNAs (lncRNAs) can act as competitive endogenous RNAs (ceRNAs) to bind to microRNAs (miRNAs), thereby affecting and regulating the expression of target genes.
Xian-xian Wu, Zhi-lin Sui, Hong-Dian Zhang, Ying Wang, Zhen-Tao Yu   +4 more
semanticscholar   +1 more source

lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

Molecular Therapy, 2021
Long non-coding RNAs (lncRNAs) play critical roles in tumorigenesis and progression of colorectal cancer (CRC). However, functions of most lncRNAs in CRC and their molecular mechanisms remain uncharacterized.
Xiaoting Lin, Shiwen Zhuang, Xue Chen, Jun Du, Longhua Zhong, Jian-Cheng Ding, Lei Wang, Jia Yi, Guo-Sheng Hu, Guo-Hui Tang, Xi Luo, Wen Liu, F. Ye   +12 more
semanticscholar   +1 more source

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang, Hong‐Cheng Wei, Lin Jiang, Yi‐Sen Shao   +3 more
wiley   +1 more source

LnCeVar: a comprehensive database of genomic variations that disturb ceRNA network regulation

, 2020
LnCeVar (http://www.bio-bigdata.net/LnCeVar/) is a comprehensive database that aims to provide genomic variations that disturb lncRNA-associated competing endogenous RNA (ceRNA) network regulation curated from the published literature and high-throughput
Wang, Yanxia, Ning, Shangwei, Li, Xia, Guo, Qiuyan, Fang, Ying, Zhang, Yunpeng, Shen, Weitao, Wang, Junwei, Gao, Yue, Li, Xin, Zhang, Guangmei, Wang, Peng, Shang, Shipeng, Zhi, Hui, Chen, Steven Xi   +14 more
core   +1 more source

Éthique de la recherche en robotique: Rapport n° 1 de la CERNA Commission de réflexion sur l’Éthique de la Recherche en sciences et technologies du Numérique d’Allistene

, 2014
La robotique, comme plus largement le numérique, débouche sur de multiples usages aux déploiements parfois aussi massifs qu’inattendus, tel l’essor actuel des drones civils. Dans ce contexte évolutif, il serait vain d’énoncer de nouvelles normes éthiques
Collectif, Cerna
core   +2 more sources

Research progress of long non-coding RNA in cutaneous squamous cell carcinoma

Pifu-xingbing zhenliaoxue zazhi, 2022
Cutaneous squamous cell carcinoma (cSCC) is one of the most common types of skin cancer. The incidence of the skin cancer is increasing year by year and seriously affects the quality of life of patients.
Xianwen LI, Ju WEN, Si QIN, Rongchang ZHENG, Huarun LI, Zhenyu LU, Mujin LI, Sihui LI   +7 more
doaj   +1 more source

The role of lncRNA-mediated ceRNA regulatory networks in liver fibrosis

Non-coding RNA Research
In the dynamic realm of molecular biology and biomedical research, the significance of long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) continues to grow, encompassing a broad spectrum of both physiological and pathological ...
Jianhao Jiang, I. Gareev, Tatiana Ilyasova, Alina Shumadalova, Weijie Du, Baofeng Yang   +5 more
semanticscholar   +1 more source