Results 71 to 80 of about 26,094 (208)

Hypoxia‐preconditioned adipose‐derived mesenchymal stem cells‐derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5‐mediated inactivation of TLR4/NF‐κB/NLRP3 inflammatory signaling

Journal of Diabetes Investigation, EarlyView.
In this study, we uncovered that Hypo‐Exo transferring H19 promoted diabetic wound healing by repressing NETs formation via the miR‐130a/b‐3p/HOXA5 pathway to inactivate the TLR4/NF‐κB/NLRP3 inflammatory signaling. ABSTRACT Background Hypoxia‐stimulated adipose‐derived mesenchymal stem cells (ADSCs)‐derived exosomes (Hypo‐Exo) have a positive impact on
Li Qian, Xianxi Meng, Bairong Fang, Li Pi   +3 more
wiley   +1 more source

Peri‐Implantitis and Periodontitis: Biological Convergence, Contextual Divergence

Journal of Periodontal Research, EarlyView.
Periodontal and peri‐implant tissues differ and coincide in many aspects, from the clinical and radiological perspective, including histology, microbiology, and molecular markers. Thus, health and disease may also follow different and similar routes.
Pablo Galindo‐Moreno, Pablo Galindo‐Fernandez, Allinson Olaechea, Francisco O'Valle, Abdusalam E. Alrmali, Hom‐Lay Wang, Miguel Padial‐Molina   +6 more
wiley   +1 more source

Identifying survival-associated ceRNA clusters in cholangiocarcinoma

Oncology Reports, 2016
Competing endogenous RNAs (ceRNAs) represent a novel layer regulations of long non-coding RNAs (lncRNAs) and genes that play important roles in cancer pathogenesis by binding microRNAs (miRNAs). However, the competition mechanism of ceRNAs in cholangiocarcinoma (CHOL) is not fully understood.
Ming, Wan, Fu-Min, Zhang, Zheng-Long, Li, Peng-Cheng, Kang, Ping-Ming, Jiang, Yi-Min, Wang, Zhi-Dong, Wang, Xiang-Yu, Zhong, Chun-Long, Li, Hao, Wang, Shi-Yong, Zhao, Yun-Fu, Cui   +11 more
openaire   +3 more sources

Dystocia in cats under UK primary emergency veterinary care: epidemiology, clinical management and outcomes

Journal of Small Animal Practice, EarlyView.
Objectives To explore the epidemiology, clinical management and outcomes for feline dystocia cases presented to UK primary emergency veterinary care. Materials and Methods Retrospective observational cross‐sectional study. Demographic and clinical data were extracted on feline dystocia cases under emergency care (2017 to 2023).
L. Leicester, D. G. O’Neill
wiley   +1 more source

Acetyl-11-keto-β-boswellic Acid Inhibits Precancerous Breast Lesion MCF-10AT Cells via Regulation of LINC00707/miR-206 that Reduces Estrogen Receptor-α

Cancer Management and Research, 2020
Xuefeng Jiang,1,* Yusheng Liu,1,* Guijuan Zhang,2,* Shujun Lin,1 Naijun Yuan,1 Jieyan Wu,1 Xianxin Yan,1 Yi Ma,3 Min Ma1,2 1College of Traditional Chinese Medicine of Jinan University, Guangzhou, People’s Republic of China; 2The First Affiliated ...
Jiang X, Liu Y, Zhang G, Lin S, Yuan N, Wu J, Yan X, Ma Y, Ma M   +8 more
doaj  

AI Public Value Creation: Data Encoding, Aggregation, and Algorithmic Computation

Public Administration, EarlyView.
ABSTRACT AI systems in public administration challenge the premise that value creation arises from managers' strategic mediation among the vertices of Moore's strategic triangle: Public value, legitimacy, and operational capacity. AI imposes new logics that reshape vertices and their interaction dynamics.
Antonio Cordella, Francesco Gualdi
wiley   +1 more source

Circular RNAs in Lotus japonicus Responses to Nutrient Supply and Mesorhizobium Symbiosis

Plant, Cell &Environment, EarlyView.
ABSTRACT Symbiotic interactions between legumes and rhizobia enable nitrogen fixation under low nutrient conditions. The establishment and function of symbiotic interactions require coordinated changes in gene expression in both the host and the microbe. Circular RNAs (circRNAs) are endogenous gene‐specific molecules that can regulate transcription and
Delecia Utley, Asa Budnick, Simona Radutoiu, Heike Sederoff   +3 more
wiley   +1 more source

LINC00963 Confers Oncogenic Properties in Glioma by Regulating the miR-506/BCAT1 Axis

Cancer Management and Research, 2020
Feng Ye, Ronghua Xu, Yuanhong Ge, Yi Zheng, Xiaowei Liu, Pingfu Deng, Xuejun Xu Department of Neurosurgery, The Second People’s Hospital of Chengdu, Chengdu, Sichuan 610021, People’s Republic of ChinaCorrespondence: Xuejun XuDepartment of ...
Ye F, Xu R, Ge Y, Zheng Y, Liu X, Deng P, Xu X   +6 more
doaj  

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Cross‐Level Regulatory Interactions Underlying Human Immune Aging

MedComm, Volume 7, Issue 7, July 2026.
We performed multi‐omics sequencing on peripheral blood samples from 69 individuals aged 23–75 years and identified multi‐layered molecular interaction networks underlying the process of immune senescence, which provides a comprehensive multi‐omics framework for understanding immune aging and identifying potential strategies to delay immunosenescence ...
Quanyou Wu, Botao Zhang, Xiaochen Zhi, Qi Zhang, Kai Zhang, Yaru Wang, Kaitai Zhang, Lin Feng, Shujun Cheng, Ting Xiao   +9 more
wiley   +1 more source