Results 71 to 80 of about 42,399 (240)
The flowchart of ceRNA network analysis. [PDF]
, 2019 The flowchart of ceRNA network analysis.
Wei-dong Jiang (7114763) +1 more
core +1 more source
, 2021 (A) An integrative pipeline for transcriptome-wide identification of lincRNA-miRNA-mRNA regulatory networks. Interactions between miRNAs and their targets are predicted using three computational approaches (miRanda, PITA and RNAhybrid). miRNA-lincRNA and
Jiaxing Chen (9107364) +13 more
core +1 more source
Research progress of long non-coding RNA in cutaneous squamous cell carcinoma
Pifu-xingbing zhenliaoxue zazhi, 2022 Cutaneous squamous cell carcinoma (cSCC) is one of the most common types of skin cancer. The incidence of the skin cancer is increasing year by year and seriously affects the quality of life of patients.
Xianwen LI +7 more
doaj +1 more source
RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment
Precision Medical Sciences, EarlyView.This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run +7 more
wiley +1 more source
Aberrant ceRNA activity drives lung cancer [PDF]
Cell Research, 2014 In a recent issue of Nature, Kumar et al. demonstrate that the oncogenic potential of the Hmga2 gene is largely due to the ability of its transcript to operate as a competing endogenous RNA in a protein coding-independent manner. The Hmga2 mRNA decoys the let-7 microRNA family to regulate Tgfbr3 expression and enhance TGF-β signaling, thereby promoting
Yvonne, Tay +2 more
openaire +2 more sources
Development of Ferroptosis-Associated ceRNA Network in Periodontitis
International Dental Journal, 2023 Periodontitis is a chronic inflammatory illness that may lead to tooth loosening and even loss, and its pathogenesis is not fully understood. Ferroptosis is an iron-dependent, regulated cell death. The present study aims to find the key ferroptosis-related genes (FRGs) in periodontitis and develop an mRNA-miRNA-lncRNA network to deeply explore the ...
Churen Zhang +3 more
openaire +3 more sources
Cancer Management and Research, 2021 Qingwei Wu, Yingying Zhao, Runjie Shi, Tao Wang Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of ChinaCorrespondence ...
Wu Q, Zhao Y, Shi R, Wang T
doaj
Allergy, EarlyView.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
Open Life Sciences, 2021 Osteosarcoma is the most common type of primary malignant tumor of the bone, with a high metastatic rate and poor prognosis. Therefore, it is important to further elucidate the molecular mechanisms involved in the development of osteosarcoma and explore ...
Zhang Xiao-rong +3 more
doaj +1 more source
Brain Pathology, EarlyView.How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova +11 more
wiley +1 more source