Results 81 to 90 of about 42,399 (240)
Integrated analysis of lncRNA-associated ceRNA network reveals potential biomarkers for the prognosis of hepatitis B virus-related hepatocellular carcinoma [PDF]
, 2019 Hongyan Li, Xiaonan Zhao, Chenghua Li, Chuanlun Sheng, Zhenzi Bai Infectious Department, China-Japan Union Hospital, Jilin University, Changchun 130033, China Background: There is evidence that abnormal expression of lncRNAs is associated with hepatitis ...
Li H, Li C, Bai Z, Sheng C, Zhao X
core
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
Cancer Management and Research, 2020 Wei-jun Chen, 1,* Liang Xiong, 2,* Lin Yang, 3 Li-juan Yang, 3 Lin Li, 3 Li Huang, 3 Xiao-qing Liang, 4 Jie Xue, 3 Bu-zhen Tan 5 1Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nanchang University, Reproductive Hospital ...
Chen W +8 more
doaj
Cancer Management and Research, 2021 Dai J, Wang B, Zhao Y, et al. Cancer Manag Res. 2020;12:12697–12708. The Editor and Publisher of Cancer Management and Research wish to publish an Expression of Concern for the published article.
Dai J +6 more
doaj
Cancer Science, EarlyView.The lncRNA CROCCP2 upregulates HOXD11 by competitively adsorbing miR‐5584‐5p, thereby promoting glioma cell proliferation, migration, and invasion by inhibiting autophagy. It significantly enhances tumor growth in vivo, suggesting it may be a potential therapeutic target for gliomas.
Feng Wang +8 more
wiley +1 more source
circMAN1A2 as an Isoform‐Resolved Circular RNA Hub in Cancer
Cancer Science, EarlyView.circMAN1A2 as an isoform‐resolved circular RNA hub in cancer. circMAN1A2 is generated by back‐splicing of MAN1A2 pre‐mRNA, with alternative circularization producing multiple isoforms, including the predominant circMAN1A2(2–5). Its mechanistic interfaces include miRNA‐associated regulation, RBP binding/proteostasis control, BSJ‐mediated RNA–RNA pairing,
Hanyu Shang +4 more
wiley +1 more source
Table_2_Characterization of Dysregulated lncRNA-Associated ceRNA Network Reveals Novel lncRNAs With ceRNA Activity as Epigenetic Diagnostic Biomarkers for Osteoporosis Risk.XLSX [PDF]
, 2020 The altered expression of long non-coding RNAs (lncRNAs) has been implicated in the development and human diseases. However, functional roles and regulatory mechanisms of lncRNA as competing endogenous RNAs (ceRNAs) in osteoporosis and their potential ...
Yina Zhang (386861) +2 more
core +1 more source
Whole-transcriptome RNA sequencing reveals global expression dynamics and ceRNA regulatory networks related to hair follicle development and melanogenesis in goats [PDF]
Animal BioscienceObjective Domestic animals, fur is a product of long-term selection by humans and the natural environment. It is generally used to distinguish between different breeds.
Junyin Zhao +4 more
doaj +1 more source
Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
Cell Proliferation, EarlyView.m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source
Epigenetics, 2023 Increasing evidence has uncovered the essential roles of long noncoding RNAs (lncRNAs) in biological and pathological functions of dendritic cells (DCs) among patients with systemic lupus erythematosus (SLE).
Mengmeng Xiang +6 more
doaj +1 more source