Results 81 to 90 of about 68,629 (274)

LncRNAs in Ovarian Cancer Progression, Metastasis, and Main Pathways: ceRNA and Alternative Mechanisms

International Journal of Molecular Sciences, 2020
Ovarian cancer (OvCa) develops asymptomatically until it reaches the advanced stages with metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of regulatory long non-coding RNAs (lncRNAs) competing with protein-coding mRNAs
E. Braga, M. Fridman, A. A. Moscovtsev, E. Filippova, A. Dmitriev, N. Kushlinskii   +5 more
semanticscholar   +1 more source

Identification of lncRNA/circRNA-miRNA-mRNA ceRNA Network as Biomarkers for Hepatocellular Carcinoma

Frontiers in Genetics, 2022
Background: Hepatocellular carcinoma (HCC) accounts for the majority of liver cancer, with the incidence and mortality rates increasing every year. Despite the improvement of clinical management, substantial challenges remain due to its high recurrence ...
Shanshan Chen, Yong-Chao Zhang, X. Ding, Wei Li   +3 more
semanticscholar   +1 more source

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

Animal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang, Qiuyang Li, Zhiying Wang, Shan Zhang, Kassahun Bekana, Qingfeng Zhang, Juanshan Zheng, Hongwei Xu, Xianyong Lan, Chuanying Pan   +9 more
wiley   +1 more source

Construction of a lncRNA–miRNA–mRNA ceRNA network.

, 2021
(A) Volcano map of 69 significant DElncRNAs. (B) Correlation between the five prognostic mRNAs and their corresponding miRNAs. (C) A ceRNA network was constructed containing five mRNAs, three miRNAs, and 69 lncRNAs for NSCLC prognosis.
Jie-Tao Lin (9377048), Wei Guo (86150), Ling-Ling Sun (443325), Hong-Xing Yang (11785983), Cai-Zhi Yang (11785977), Zhong-Yu Huang (11785980), Xi Xiao (623637), Shan Liu (193759), Li Deng (442821), Li-Zhu Lin (9377066), Lei-Hao Hu (11424073)   +10 more
core   +1 more source

Circular RNA Circ-ZNF609 Promotes Lung Adenocarcinoma Proliferation by Modulating miR-1224-3p/ETV1 Signaling

Cancer Management and Research, 2020
Yangsong Zuo,1,* Wenyi Shen,1,* Chengshi Wang,1,* Niu Niu,2,* Juan Pu1 1Department of Radiation, Lianshui People’s Hospital Affiliated to Kangda College of Nanjing Medical University, Huai’an, People’s Republic of China; 2Cancer ...
Zuo Y, Shen W, Wang C, Niu N, Pu J
doaj  

Construction of circRNA–miRNA–mRNA ceRNA regulatory network and screening of diagnostic targets for tuberculosis

Annals medicus
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb), which threatens human health and safety all over the world. Hundreds of thousands of people die from TB every year.
Xinyi Pu, Si-Yu Sheng, Yu-Juan Fu, Yue Yang, Guangyu Xu   +4 more
semanticscholar   +1 more source

Identification of Immune-Related Gene Signature and Prediction of CeRNA Network in Active Ulcerative Colitis

Frontiers in Immunology, 2022
Background Ulcerative colitis (UC) is an inflammatory disease of the intestinal mucosa, and its incidence is steadily increasing worldwide. Intestinal immune dysfunction has been identified as a central event in UC pathogenesis.
Mengmeng Xu, Ying Kong, Nannan Chen, Wen-Yan Peng, Rui-Dong Zi, Man-Man Jiang, Jin-Feng Zhu, Yuting Wang, Ji-Cheng Yue, Jinrong Lv, Yuan-Yuan Zeng, Y. Chin   +11 more
semanticscholar   +1 more source

Research Progress of Berberine in Kidney Disease: Targeting Mitochondria and Ferroptosis

iNew Medicine, EarlyView.
This figure illustrates the model‐specific renoprotective mechanisms of berberine (BBR) across three major kidney diseases. From left to right, the diagram shows that BBR targets distinct core pathways depending on the pathological context: in diabetic nephropathy (DN), BBR activates AMPK to improve mitochondrial energy metabolism; in acute kidney ...
Liuqing Wang, Rongyu Guo, Xiaojun Feng, Liqin Tang   +3 more
wiley   +1 more source

Peran Mikrobiota Saluran Cerna pada Artritis Reumatoid [PDF]

, 2021
Artritis rheumatoid merupakan suatu penyakit autoimun yang ditandai dengan adanya proses inflamasi kronis sistemik dan berakibat pada kerusakan sendi. Mekanisme etiopatogenik yang menyebabkan inflamasi yang sangat kompleks dan melibatkan berbagai faktor,
Eldy, Eldy, Felicia, Clarissa, Tjahyanto, Teddy, Niaga, Karmenia Jessica Kurnia   +3 more
core   +1 more source

Cucurbitacin B regulates lung cancer cell proliferation and apoptosis via inhibiting the IL-6/STAT3 pathway through the lncRNA XIST/miR-let-7c axis

Pharmaceutical Biology, 2022
Context Lung cancer, the most common type of cancer, has a high mortality rate. Cucurbitacin B (CuB), a natural compound extracted from Cucurbitaceae plants, has antitumor effects.
Jian-Hua Liu, Chen Li, Liang Cao, Chang-Hong Zhang, Zhi-Hua Zhang   +4 more
doaj   +1 more source