Results 61 to 70 of about 26,094 (208)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
Whole-transcriptome RNA sequencing reveals global expression dynamics and ceRNA regulatory networks related to hair follicle development and melanogenesis in goats [PDF]
Animal BioscienceObjective Domestic animals, fur is a product of long-term selection by humans and the natural environment. It is generally used to distinguish between different breeds.
Junyin Zhao +4 more
doaj +1 more source
Cancer Science, EarlyView.Transcriptomic profiling of CD34+ cells from AML patients relapsing after allo‐HSCT reveals lncRNA‐driven ceRNA networks, with the SNHG8‐miR‐625‐ZC3H13/15 axis identified as a key relapse‐promoting module through CRISPR screening and single‐cell perturbation.
Fei Zhao +14 more
wiley +1 more source
Cancer Science, EarlyView.The lncRNA CROCCP2 upregulates HOXD11 by competitively adsorbing miR‐5584‐5p, thereby promoting glioma cell proliferation, migration, and invasion by inhibiting autophagy. It significantly enhances tumor growth in vivo, suggesting it may be a potential therapeutic target for gliomas.
Feng Wang +8 more
wiley +1 more source
Comprehensive Diagnostics of Diabetic Nephropathy by Transcriptome RNA Sequencing
Diabetes, Metabolic Syndrome and Obesity, 2022 Lei Lei,1 Yihua Bai,1 Yang Fan,1 Yaling Li,1 Hongying Jiang,1 Jiaping Wang2 1Department of Nephrology, The Second Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, People’s Republic of China; 2Department of Radiology, The Second ...
Lei L +5 more
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The Incarnational Aesthetic of David Brown☆
International Journal of Systematic Theology, EarlyView.Abstract The notion of incarnation has historically been a prominent concept for the acceptance of images and the interpretation of art within Christianity. A contemporary proponent of this line of reasoning about the theological potential of art is David Brown, who builds his theology of culture on the doctrine of incarnation. This article presents an
Filip Taufer
wiley +1 more source
Clinical and Experimental Obstetrics & GynecologyBackground: Endometriosis (EM), a gynecological disorder that is dependent on estrogen and causes inflammation, is prevalent among women of reproductive age and is considered a chronic condition.
Yan Huang +3 more
doaj +1 more source
Construction of a circRNA-Mediated ceRNA Network Reveals Novel Biomarkers for Aortic Dissection
International Journal of General Medicine, 2022 De-Bin Liu,1,* You-Fu He,2– 4,* Gui-Jian Chen,1 Hua Huang,1 Xu-Ling Xie,1 Wan-Jun Lin,1 Zhi-Jian Peng1 1Department of Cardiology, The Second People’s Hospital of Shantou, Shantou, Guangdong Province, People’s Republic of China; 2Department of ...
Liu DB +6 more
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Journal of Inflammation Research, 2023 Nan Zhang,1,* Gui-yuan Song,2,3,* Yong-jian Hu,4 Xia Wang,4 Tian-zhu Chao,1 Yao-yao Wu,1 Ping Xu1 1School of Food and Biomedicine, Zaozhuang University, Zaozhuang, Shandong, 277160, People’s Republic of China; 2School of Public Health, Weifang ...
Zhang N +6 more
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PLOS ONE, 2017 Recent findings have identified competing endogenous RNAs (ceRNAs) as the drivers in many disease conditions, including cancers. The ceRNAs indirectly regulate each other by reducing the amount of microRNAs (miRNAs) available to target messenger RNAs (mRNAs). The ceRNA interactions mediated by miRNAs are modulated by a titration mechanism, i.e.
Conte F +5 more
openaire +8 more sources