Results 61 to 70 of about 91,818 (279)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

Recent Advances in Thalassemia Research: A Comprehensive Assessment From Diagnostic Technologies to Clinical Treatment

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thalassemia, a common hereditary blood disorder causing impaired globin synthesis and related complications, has seen remarkable progress in recent years due to advancements in genomics and molecular biology. Researchers have identified various gene variants related to thalassemia and improved clinical diagnostic methods, including new genetic testing ...
Chaoqiong Zhou   +7 more
wiley   +1 more source

LncRNA SNHG16 Facilitates Nasopharyngeal Carcinoma Progression by Acting as ceRNA to Sponge miR-520a-3p and Upregulate MAPK1 Expression

open access: yesCancer Management and Research, 2021
Qingwei Wu, Yingying Zhao, Runjie Shi, Tao Wang Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of ChinaCorrespondence ...
Wu Q, Zhao Y, Shi R, Wang T
doaj  

Research progress of long non-coding RNA in cutaneous squamous cell carcinoma

open access: yesPifu-xingbing zhenliaoxue zazhi, 2022
Cutaneous squamous cell carcinoma (cSCC) is one of the most common types of skin cancer. The incidence of the skin cancer is increasing year by year and seriously affects the quality of life of patients.
Xianwen LI   +7 more
doaj   +1 more source

Convocation

open access: yes, 2014
The origins of phenotypic variation within mimetic Heliconius butterflies have long fascinated biologists and naturalists. However, the evolutionary processes that have generated this extraordinary diversity remain puzzling. Here we examine intraspecific
Arias, Carlos F.   +6 more
core   +2 more sources

Selecting Promising Soil Quality Indicators for Monitoring Soil Management Effects Based on 10 European Long‐Term Field Experiments

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background: Soil quality can be measured through soil quality indicators that reflect soil processes. Aim: The aim of this study was to (1) identify a limited set of soil quality indicators that are most sensitive to agricultural soil management and that are widely applicable regardless of pedo‐climatic conditions, and (2) link common ...
Giulia Bongiorno   +14 more
wiley   +1 more source

High-throughput validation of ceRNA regulatory networks

open access: yesBMC Genomics, 2017
Background: MicroRNAs (miRNAs) play multiple roles in tumor biology [1]. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration [2]. Specifically, computational models predicted [3, 4] and experimental assays confirmed [5, 6] that miRNA activity is dependent on miRNA target
Hua-Sheng Chiu   +7 more
openaire   +4 more sources

TET3‐Mediated m5C Modification of CCAT2 Accelerates Cardiac Microvascular Endothelial Cell Damage in Acute Coronary Syndrome

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu   +5 more
wiley   +1 more source

Silencing of LINC00707 suppresses cell proliferation, migration, and invasion of osteosarcoma cells by modulating miR-338-3p/AHSA1 axis

open access: yesOpen Life Sciences, 2021
Osteosarcoma is the most common type of primary malignant tumor of the bone, with a high metastatic rate and poor prognosis. Therefore, it is important to further elucidate the molecular mechanisms involved in the development of osteosarcoma and explore ...
Zhang Xiao-rong   +3 more
doaj   +1 more source

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