Results 41 to 50 of about 47,379 (197)

Integrated analysis of lncRNA-miRNA-mRNA ceRNA network in human aortic dissection

, 2021
Background Many studies on long chain non-coding RNAs (lncRNAs) are published in recent years. But the roles of lncRNAs in aortic dissection (AD) are still unclear and should be further examined.
Panpan Guo, Liu, Qingyang, Xiaotong Song, Zhang, Jian, Guo, Panpan, Han, Yanshuo, Hao Zhang, Tu, Simei, Simei Tu, Fanxing Yin, Zhang, Hao, Yin, Fanxing, Bian, Ce, Ce Bian, Chen Chen, Song, Xiaotong, Chen, Chen, Jian Zhang, Yanshuo Han, Qingyang Liu   +19 more
core   +1 more source

LncRNA SNHG16 Facilitates Nasopharyngeal Carcinoma Progression by Acting as ceRNA to Sponge miR-520a-3p and Upregulate MAPK1 Expression

Cancer Management and Research, 2021
Qingwei Wu, Yingying Zhao, Runjie Shi, Tao Wang Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of ChinaCorrespondence ...
Wu Q, Zhao Y, Shi R, Wang T
doaj  

From traditional practice to unsustainable exploitation: Fruit overharvesting on the endangered relict palm Jubaea chilensis

PLANTS, PEOPLE, PLANET, EarlyView.
Overharvesting of wild edible plants poses a growing threat to plant populations worldwide, particularly for slow‐growing species with limited regeneration. We quantified fruit extraction from the third‐largest known population of Jubaea chilensis—an endangered palm endemic to Chile—modeled the critical harvest threshold, and assessed consumer ...
Sebastián Cordero, Francisca Gálvez, Marisol Arriagada‐Honores, Andrés Jesús Garrido, Daniela Paredes‐Muñoz, Bastián Fuentes‐Valdés, Fernanda Torres‐Cifuentes, Francisco E. Fontúrbel   +7 more
wiley   +1 more source

miRTissue ce : extending miRTissue web service with the analysis of ceRNA-ceRNA interactions

, 2020
Background Non-coding RNAs include different classes of molecules with regulatory functions. The most studied are microRNAs (miRNAs) that act directly inhibiting mRNA expression or protein translation through the interaction with a miRNAs-response ...
Massimo La Rosa, Riccardo Rizzo, Alfonso Urso, Antonino Fiannaca, Laura La Paglia   +4 more
core   +1 more source

Silencing of LINC00707 suppresses cell proliferation, migration, and invasion of osteosarcoma cells by modulating miR-338-3p/AHSA1 axis

Open Life Sciences, 2021
Osteosarcoma is the most common type of primary malignant tumor of the bone, with a high metastatic rate and poor prognosis. Therefore, it is important to further elucidate the molecular mechanisms involved in the development of osteosarcoma and explore ...
Zhang Xiao-rong, Shao Jian-li, Li Heng, Wang Liang   +3 more
doaj   +1 more source

Therapeutic Properties and Underlying Mechanisms of Traditional Chinese Medicine in Managing Rheumatoid Arthritis: An Integrative Review of Clinical and Molecular Findings

Phytotherapy Research, EarlyView.
The translational research framework integrating TCM for RA. The figure outlines a stepwise framework for the modernization and clinical translation of TCM in RA. Part 1 highlights the inheritance and development of TCM theory, including classical medical texts, traditional herbal knowledge, and syndrome differentiation–based treatment principles. Part
Jianting Wen, Jian Liu, Lei Wan, Fanfan Wang, Yang Li   +4 more
wiley   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source

Long Non-Coding RNA LINC01783 Promotes the Progression of Cervical Cancer by Sponging miR-199b-5p to Mediate GBP1 Expression

Cancer Management and Research, 2020
Wei-jun Chen, 1,* Liang Xiong, 2,* Lin Yang, 3 Li-juan Yang, 3 Lin Li, 3 Li Huang, 3 Xiao-qing Liang, 4 Jie Xue, 3 Bu-zhen Tan 5 1Department of Gynaecology and Obstetrics, The Second Affiliated Hospital of Nanchang University, Reproductive Hospital ...
Chen W, Xiong L, Yang L, Yang L, Li L, Huang L, Liang X, Xue J, Tan B   +8 more
doaj  

Long Noncoding RNA LINC01426 Sequesters microRNA-519d-5p to Promote Non-Small Cell Lung Cancer Progression by Increasing ETS1 Expression [Expression of Concern]

Cancer Management and Research, 2021
Dai J, Wang B, Zhao Y, et al. Cancer Manag Res. 2020;12:12697–12708. The Editor and Publisher of Cancer Management and Research wish to publish an Expression of Concern for the published article.
Dai J, Wang B, Zhao Y, Zuo X, Cui H, Chen X, Liu X   +6 more
doaj  

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity

Brain Pathology, EarlyView.
How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova, Ondrej Bernatik, Katarina Cimborova, Martin Barak, Michal Hendrych, Karolina Kocourkova, Marie Sulcova, Jaroslav Olha, Katerina Amruz Cerna, Zdenek Hodny, Radim Jancalek, Dasa Bohaciakova   +11 more
wiley   +1 more source