Results 31 to 40 of about 26,094 (208)

Interactions between Distant ceRNAs in Regulatory Networks [PDF]

Biophysical Journal, 2014
Competing endogenous RNAs (ceRNAs) were recently introduced as RNA transcripts that affect each other's expression level through competition for their microRNA (miRNA) coregulators. This stems from the bidirectional effects between miRNAs and their target RNAs, where a change in the expression level of one target affects the level of the miRNA ...
Mor Nitzan, Avital Steiman-Shimony, Yael Altuvia, Ofer Biham, Hanah Margalit   +4 more
openaire   +3 more sources

The ceRNA network of lncRNA and miRNA in lung cancer [PDF]

Genomics & Informatics, 2020
Since lung cancer is a major causative for cancer-related deaths, the investigations for discovering biomarkers to diagnose at an early stage and to apply therapeutic strategies have been continuously conducted. Recently, long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) are being exponentially studied as promising biomarkers of lung cancer ...
Seo, Danbi, Kim, Dain, Chae, Yeonsoo, Kim, Wanyeon   +3 more
openaire   +2 more sources

Características do anestésico alternativo de erva cidreira (Lippia alba) e alecrim pimenta (Lippia sidoides) em peixes

Medicina Veterinária, 2020
Existem anestésicos efetivos para peixes, mas é importante buscar alternativas de substâncias de fácil aquisição e baixo custo aos piscicultores e que não ofereçam riscos à saúde aos animais e manipuladores. Por se tratar de um produto de origem natural,
Arlene Sobrinho Ventura, Tarcila Souza de Castro Silva, Claudia Andrea Lima Cardoso, Luis Antônio Kioshi Aoki Inoue   +3 more
doaj  

High temperature photoluminescence sensitivity of Te4+ in silver nanoparticle tellurite glasses: Application as optical temperature sensor

Next Materials
Tellurite glasses with the composition (in mol%) (100-x)(75TeO2:25Li2O):xAgNO3 (x = 0, 0.6, and 1.2) were synthesized at 800 °C in an ambient atmosphere, for investigation of the influence of Ag nanoparticles on the Te4+ semi metal ion photoluminescence (
Adriana do Carmo Capiotto, Luis Humberto da Cunha Andrade, Junior Reis Silva, Luiz Antonio de Oliveira Nunes, Sandro Marcio Lima   +4 more
doaj   +1 more source

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

Identification of circRNA-miRNA-mRNA Regulatory Network and Autophagy Interaction Network in Atrial Fibrillation Based on Bioinformatics Analysis

International Journal of General Medicine, 2021
Xiaoying Chao,1,* Weiran Dai,1,* Shuo Li,1 Chenyang Jiang,1 Zhiyuan Jiang,2 Guoqiang Zhong1 1Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 2Hypertension ...
Chao X, Dai W, Li S, Jiang C, Jiang Z, Zhong G   +5 more
doaj  

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Perdarahan Saluran Cerna Atas

Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran, 2023
Upper gastrointestinal hemorrhage (PSCA) is bleeding from the lumen of the proximal gastrointestinal tract above the treitz ligament. The causes of PSCA can be classified into variceal bleeding and non-variceal bleeding. The most common causes of upper gastrointestinal bleeding are peptic ulcers, esophageal-gastric variceal veins, ulcerative ...
null Darmadi Darmadi, null Sania Audry Nasution   +1 more
openaire   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

LncRSFD Alternative Splicing Modulates the Proliferation and Differentiation of Adipocytes Through Sponging miRNAs

Animal Research and One Health, EarlyView.
This study identified a molecule named lncRSFD, which is highly expressed in sheep adipose tissues. The lncRSFD gene generates two distinct transcript variants via alternative splicing: lncRSFD‐L and lncRSFD‐S. Functionally, lncRSFD alternative splicing (lncRSFD‐L/S) promotes the proliferation, differentiation, and lipid metabolism of adipocytes ...
Jinpeng Wang, Qiuyang Li, Zhiying Wang, Shan Zhang, Kassahun Bekana, Qingfeng Zhang, Juanshan Zheng, Hongwei Xu, Xianyong Lan, Chuanying Pan   +9 more
wiley   +1 more source