From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition [PDF]
RNA is believed to have been the first reservoir of genetic information, but despite its ancient history, RNA continues to fascinate and is only now beginning to be understood in its entire variety and communication modality. New discoveries include the pseudogene RNA network regulating PTEN transcription and translation and the identification of ...
TAULLI, Riccardo +2 more
openaire +1 more source
lncRNA-mediated ceRNA network in bladder cancer
Bladder cancer is a common disease associated with high rates of morbidity and mortality. Although immunotherapy approaches such as adoptive T-cell therapy and immune checkpoint blockade have been investigated for the treatment of bladder cancer, their off-target effects and ability to affect only single targets have led to clinical outcomes that are ...
Kun Li, Tongyue Yao, Ziqiang Wang
openaire +3 more sources
Transcription Profiling of a Revealed the Potential Molecular Mechanism of Governor Vessel Electroacupuncture for Spinal Cord Injury in Rats [PDF]
Objective This study aimed to identify differentially expressed genes (DEGs) by transcriptome analysis to elucidate a potential mechanism by which governor vessel electroacupuncture (GV-EA) promotes neuronal survival, axonal regeneration, and functional ...
Xingru Xiao +7 more
doaj +1 more source
Selective photoexcitation of exciton-polariton vortices [PDF]
We resonantly excite exciton-polariton states confined in cylindrical traps. Using a homodyne detection setup, we are able to image the phase and amplitude of the confined polariton states. We evidence the excitation of vortex states, carrying an integer
Deveaud-Plédran, Benoît +5 more
core +2 more sources
Identification of circular RNA expression profiles in renal fibrosis induced by obstructive injury
Introduction Advancing renal fibrosis is the common histopathological feature of chronic obstructive nephropathy, representing the final pathway of nearly all chronic and progressive nephropathies.
Jiangju Huang +7 more
doaj +1 more source
Therapeutic prospects of ceRNAs in COVID-19
Since the end of 2019, COVID-19 caused by SARS-CoV-2 has spread worldwide, and the understanding of the new coronavirus is in a preliminary stage. Currently, immunotherapy, cell therapy, antiviral therapy, and Chinese herbal medicine have been applied in the clinical treatment of the new coronavirus; however, more efficient and safe drugs to control ...
Lin Liu +35 more
openaire +3 more sources
Bifidobakterium dan Kesehatan Saluran Cerna Anak [PDF]
Kolonosisasi mikrobiota saluran cerna yang didominasi oleh mikrobiota sehat merupakan aspek penting dalam optimalisasi kesehatan anak. Komposisi mikrobiota saluran cerna selalu berubah pada setiap keadaan karena banyak faktor yang memengaruhinya. Bifidobacteria terdapat dalam Air Susu Ibu dan mendominasi saluran cerna bayi yang mendapat ASI eksklusif ...
Reza Ranuh, Badriul Hegar
openaire +2 more sources
The miR-223 host non-coding transcript linc-223 induces IRF4 expression in acute myeloid leukemia by acting as a competing endogenous RNA [PDF]
Alterations in genetic programs required for terminal myeloid differentiation and aberrant proliferation characterize acute myeloid leukemia (AML) cells.
Bozzoni, Irene +8 more
core +2 more sources
Kinetic modelling of competition and depletion of shared miRNAs by competing endogenous RNAs
Non-conding RNAs play a key role in the post-transcriptional regulation of mRNA translation and turnover in eukaryotes. miRNAs, in particular, interact with their target RNAs through protein-mediated, sequence-specific binding, giving rise to extended ...
A Arvey +101 more
core +2 more sources
Perdarahan Saluran Cerna pada Anak dengan Penyakit Ginjal Tahap Akhir
Penyakit ginjal tahap akhir (PGTA) adalah penyakit ginjal kronik (PGK) stadium 5 yang ditandai dengan laju filtrasi glomerulus (LFG) < 15 mL/menit/1,73m2 selama tiga bulan atau lebih, atau suatu kondisi dengan pasien memerlukan terapi pengganti ginjal ...
Beatrix Siregar +2 more
doaj +1 more source

