Results 11 to 20 of about 68,629 (274)
miRTissue ce : extending miRTissue web service with the analysis of ceRNA-ceRNA interactions [PDF]
BMC Bioinformatics, 2020 Background Non-coding RNAs include different classes of molecules with regulatory functions. The most studied are microRNAs (miRNAs) that act directly inhibiting mRNA expression or protein translation through the interaction with a miRNAs-response ...
Massimo La Rosa +4 more
core +6 more sources
The multilayered complexity of ceRNA crosstalk and competition [PDF]
Nature, 2014 Recent reports have described an intricate interplay among diverse RNA species, including protein-coding messenger RNAs and non-coding RNAs such as long non-coding RNAs, pseudogenes and circular RNAs.
Y. Tay, J. Rinn, P. Pandolfi
semanticscholar +3 more sources
, 2021 Pools of RNA molecules can act as competing endogenous RNAs (ceRNAs) and indirectly alter their expression levels by competitively binding shared microRNAs.
Sibilio P. +9 more
core +4 more sources
Perdarahan Saluran Cerna pada Anak dengan Penyakit Ginjal Tahap Akhir [PDF]
Sari Pediatri, 2023 Penyakit ginjal tahap akhir (PGTA) adalah penyakit ginjal kronik (PGK) stadium 5 yang ditandai dengan laju filtrasi glomerulus (LFG) < 15 mL/menit/1,73m2 selama tiga bulan atau lebih, atau suatu kondisi dengan pasien memerlukan terapi pengganti ginjal ...
Beatrix Siregar +2 more
doaj +2 more sources
Long Non‐Coding RNAs: Key Regulators of Economic Traits in Livestock From Mechanisms to Breeding Applications [PDF]
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.Long non‐coding RNAs (lncRNAs) act as key regulators of economically important traits in livestock through diverse mechanisms including ceRNA networks, epigenetic regulation (X‐inactivation and imprinting) and liquid–liquid phase separation (LLPS).
Keyvan Khani +2 more
wiley +2 more sources
Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer [PDF]
PLOS ONE, 2017 Recent findings have identified competing endogenous RNAs (ceRNAs) as the drivers in many disease conditions, including cancers. The ceRNAs indirectly regulate each other by reducing the amount of microRNAs (miRNAs) available to target messenger RNAs ...
Giulia Fiscon (3440045) +35 more
core +9 more sources
lncRNA-mediated ceRNA network in bladder cancer
Non-coding RNA Research, 2022 Bladder cancer is a common disease associated with high rates of morbidity and mortality. Although immunotherapy approaches such as adoptive T-cell therapy and immune checkpoint blockade have been investigated for the treatment of bladder cancer, their ...
Kun Li, Tong-Han Yao, Zi-Qiang Wang
semanticscholar +4 more sources
LINC01537 Regulates Malignant Phenotypes and Predicts Prognosis in Breast Cancer, and Its Bioinformatics Analysis [PDF]
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.LINC01537 is upregulated in breast cancer, predicting poor prognosis; it acts as a ceRNA sponging miR‐138‐5p to upregulate EZH2, promoting breast cancer progression via this axis. ABSTRACT Breast cancer is a highly heterogeneous malignancy and constitutes one of the leading health threats to women globally.
Yuetong Guo, Libo Shi
wiley +2 more sources
High-throughput validation of ceRNA regulatory networks
BMC Genomics, 2017 Background MicroRNAs (miRNAs) play multiple roles in tumor biology. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration.
Pavel Sumazin +7 more
core +5 more sources
Deciphering the rules of ceRNA networks [PDF]
Proceedings of the National Academy of Sciences, 2013 Recent theoretical and experimental studies have shed light on the complex network of interactions among the multiple classes of RNA within the cell. Although much of the focus over the past decade has been on the mechanisms by which microRNAs (miRNA) regulate the stability and translation of messenger RNAs (mRNAs), more recently it has come to light ...
Marcella, Cesana, George Q, Daley
openaire +4 more sources