Results 21 to 30 of about 68,629 (274)
Roles of ncRNAs as ceRNAs in Gastric Cancer [PDF]
Genes, 2021 Although ignored in the past, with the recent deepening of research, significant progress has been made in the field of non-coding RNAs (ncRNAs). Accumulating evidence has revealed that microRNA (miRNA) response elements regulate RNA. Long ncRNAs, circular RNAs, pseudogenes, miRNAs, and messenger RNAs (mRNAs) form a competitive endogenous RNA (ceRNA ...
Junhong Ye, Jifu Li, Ping Zhao
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From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition [PDF]
Nature Structural & Molecular Biology, 2013 RNA is believed to have been the first reservoir of genetic information, but despite its ancient history, RNA continues to fascinate and is only now beginning to be understood in its entire variety and communication modality. New discoveries include the pseudogene RNA network regulating PTEN transcription and translation and the identification of ...
TAULLI, Riccardo +2 more
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Long noncoding RNA NEAT1 promotes ferroptosis by modulating the miR-362-3p/MIOX axis as a ceRNA
Cell Death and Differentiation, 2022 Ferroptosis, a novel form of regulated cell death induced by iron-dependent lipid peroxidation, plays an essential role in the development and drug resistance of tumors.
Ying Zhang +4 more
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Translating ceRNA susceptibilities into correlation functions [PDF]
Biophysical Journal, 2017 Competition to bind microRNAs induces an effective positive crosstalk between their targets, therefore known as ‘competing endogenous RNAs’ or ceRNAs. While such an effect is known to play a significant role in specific situations, estimating its strength from data and, experimentally, in physiological conditions appears to be far ...
Martirosyan, A. +2 more
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Molecular Cancer, 2022 Background Esophageal squamous cell carcinoma (ESCC) is a common invasive malignancy worldwide with poor clinical outcomes. Increasing amount of long non-coding RNAs (lncRNAs) have been reported to be involved in cancer development. However, lncRNAs that
Song-tao Xue +6 more
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ceRNAs: miRNA Target Mimic Mimics [PDF]
Cell, 2011 In a recent issue of Cell, four papers described regulatory interactions among messenger RNAs (mRNAs) that share target sequences for the same microRNAs (miRNAs) (Cesana et al., 2011; Karreth et al., 2011; Sumazin et al., 2011; Tay et al., 2011). The authors state that these mRNAs, dubbed “competing endogenous RNAs (ceRNAs),” define a new layer of ...
Rubio-Somoza, I. +4 more
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Frontiers in Immunology, 2023 Background Pre-mRNA processing factor 19 (PRPF19) is an E3 ligase that plays a crucial role in repairing tumor-damaged cells and promoting cell survival.
Ya-Xuan Wang +7 more
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An In Silico Approach to Define Potential Biomarkers of miRNA-Associated ceRNAs for Breast Cancer
Cumhuriyet Science Journal, 2023 Breast cancer (BC) is the most common type of cancer with the highest incidence in women. Particularly in breast cancer, competing endogenous RNAs (ceRNAs) play crucial roles in a variety of metabolic pathways including proliferation, migration, and ...
Serap Ozer Yaman, Sema Mısır
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Nucleic Acids Res., 2013 Although microRNAs (miRNAs), other non-coding RNAs (ncRNAs) (e.g. lncRNAs, pseudogenes and circRNAs) and competing endogenous RNAs (ceRNAs) have been implicated in cell-fate determination and in various human diseases, surprisingly little is known about ...
Junhao Li +4 more
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Identification of a lncRNA/circRNA-miRNA-mRNA ceRNA Network in Alzheimer's Disease.
Journal of Integrative Neuroscience, 2023 BACKGROUND Alzheimer's disease (AD) occurs in the elderly and pre-elderly, characterized by decline of memory, cognitive dysfunction, impairment of learning capacity, and motor dysfunction.
Li-ning Su +3 more
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