Results 21 to 30 of about 42,399 (240)

The ceRNA regulation landscape across malignant tumors. [PDF]

, 2023
(a) The number of ncRNA-related ceRNA interactions in each malignant tumor. (b) The topological characteristics of ncRNA-related ceRNA networks for the 31 malignant tumors. The Degree column is the p-value of fitting power-law distribution.
Lin Liu (74495), Junpeng Zhang (173071), Xuemei Wei (9405264), Sijing Li (1623253), Chunwen Zhao (6691496), Jiuyong Li (761435), Thuc Duy Le (8755443)   +6 more
core   +1 more source

From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition [PDF]

Nature Structural & Molecular Biology, 2013
RNA is believed to have been the first reservoir of genetic information, but despite its ancient history, RNA continues to fascinate and is only now beginning to be understood in its entire variety and communication modality. New discoveries include the pseudogene RNA network regulating PTEN transcription and translation and the identification of ...
R. Taulli, C. Loretelli, P. P. Pandolfi
openaire   +1 more source

ceRNAs: miRNA Target Mimic Mimics [PDF]

Cell, 2011
In a recent issue of Cell, four papers described regulatory interactions among messenger RNAs (mRNAs) that share target sequences for the same microRNAs (miRNAs) (Cesana et al., 2011; Karreth et al., 2011; Sumazin et al., 2011; Tay et al., 2011). The authors state that these mRNAs, dubbed “competing endogenous RNAs (ceRNAs),” define a new layer of ...
Rubio-Somoza, I., Weigel, D., Franco-Zorilla, J., García, J., Paz-Ares, J.   +4 more
openaire   +3 more sources

Translating ceRNA susceptibilities into correlation functions [PDF]

Biophysical Journal, 2017
Competition to bind microRNAs induces an effective positive crosstalk between their targets, therefore known as ‘competing endogenous RNAs’ or ceRNAs. While such an effect is known to play a significant role in specific situations, estimating its strength from data and, experimentally, in physiological conditions appears to be far ...
Martirosyan, A., Marsili, M., De Martino, A.   +2 more
openaire   +4 more sources

Construction of ceRNA regulatory networks for osteoporosis

Molecular Medicine Reports, 2023
Osteoporosis increases the risk of fracture. Improving the diagnosis and treatment of osteoporosis has clinical applications. The differentially expressed genes (DEcircRs, DEmRs, DEmiRs) of osteoporotic patients and controls were analyzed using the GEO database, and enrichment analysis of DEmRs was performed. circRNAs and mRNAs, which were predicted to
Chen, Hongtao, Wang, Hailong, Liu, Xu, Li, Long, Abudusimu, Yiliyaer, Tuoheti, Yilihamu   +5 more
openaire   +2 more sources

Research Ethics in Machine Learning [PDF]

, 2018
Members of the Machine Learning working group : Laurence Devillers, Professeur Paris-Sorbonne 4, LIMSI-CNRS, CERNA, animatrice du groupe Serge Abiteboul, Directeur de recherche Inria, ENS-Paris, Membre de l’Académie des sciences Danièle Bourcier ...
Collectif, CERNA
core   +4 more sources

Construction and dissection of the ceRNA‑ceRNA network reveals critical modules in depression

Molecular Medicine Reports, 2019
The prevalence of mental health disorders such as depression is high. Depression is a multifactorial disorder and its underlying mechanisms remain unclear. Competing endogenous RNA (ceRNA) regulation has been reported to serve important roles in human disease.
Lang, Yan, Zhang, Jingchao, Yuan, Zheng
openaire   +3 more sources

Integrated analysis of lncRNA-miRNA-mRNA ceRNA network in human aortic dissection [PDF]

, 2021
Background Many studies on long chain non-coding RNAs (lncRNAs) are published in recent years. But the roles of lncRNAs in aortic dissection (AD) are still unclear and should be further examined.
Panpan Guo, Liu, Qingyang, Xiaotong Song, Zhang, Jian, Guo, Panpan, Han, Yanshuo, Hao Zhang, Tu, Simei, Simei Tu, Fanxing Yin, Zhang, Hao, Yin, Fanxing, Bian, Ce, Ce Bian, Chen Chen, Song, Xiaotong, Chen, Chen, Jian Zhang, Yanshuo Han, Qingyang Liu   +19 more
core   +1 more source

The mRNA related ceRNA–ceRNA landscape and significance across 20 major cancer types [PDF]

Nucleic Acids Research, 2015
Cross-talk between competitive endogenous RNAs (ceRNAs) through shared miRNAs represents a novel layer of gene regulation that plays important roles in the physiology and development of cancers. However, a global view of their system-level properties across various types of cancers is still unknown.
Xu, Juan, Li, Yongsheng, Lu, Jianping, Pan, Tao, Ding, Na, Wang, Zishan, Shao, Tingting, Zhang, Jinwen, Wang, Lihua, Li, Xia   +9 more
openaire   +2 more sources

Peran Mikrobiota Saluran Cerna pada Artritis Reumatoid [PDF]

, 2021
Artritis rheumatoid merupakan suatu penyakit autoimun yang ditandai dengan adanya proses inflamasi kronis sistemik dan berakibat pada kerusakan sendi. Mekanisme etiopatogenik yang menyebabkan inflamasi yang sangat kompleks dan melibatkan berbagai faktor,
Eldy, Eldy, Felicia, Clarissa, Tjahyanto, Teddy, Niaga, Karmenia Jessica Kurnia   +3 more
core   +2 more sources