Results 21 to 30 of about 26,094 (208)

The multilayered complexity of ceRNA crosstalk and competition [PDF]

Nature, 2014
Recent reports have described an intricate interplay among diverse RNA species, including protein-coding messenger RNAs and non-coding RNAs such as long non-coding RNAs, pseudogenes and circular RNAs. These RNA transcripts act as competing endogenous RNAs (ceRNAs) or natural microRNA sponges - they communicate with and co-regulate each other by ...
Yvonne, Tay, John, Rinn, Pier Paolo, Pandolfi   +2 more
openaire   +2 more sources

Therapeutic prospects of ceRNAs in COVID-19

Frontiers in Cellular and Infection Microbiology, 2022
Since the end of 2019, COVID-19 caused by SARS-CoV-2 has spread worldwide, and the understanding of the new coronavirus is in a preliminary stage. Currently, immunotherapy, cell therapy, antiviral therapy, and Chinese herbal medicine have been applied in the clinical treatment of the new coronavirus; however, more efficient and safe drugs to control ...
Lin Liu, Lin Liu, Lin Liu, Yao Zhang, Yao Zhang, Yao Zhang, Yu Chen, Yu Chen, Yu Chen, Yueshui Zhao, Yueshui Zhao, Yueshui Zhao, Jing Shen, Jing Shen, Jing Shen, Xu Wu, Xu Wu, Xu Wu, Mingxing Li, Mingxing Li, Mingxing Li, Meijuan Chen, Xiaobing Li, Yuhong Sun, Li Gu, Wanping Li, Fang Wang, Lei Yao, Zhuo Zhang, Zhangang Xiao, Zhangang Xiao, Zhangang Xiao, Zhangang Xiao, Fukuan Du, Fukuan Du, Fukuan Du   +35 more
openaire   +3 more sources

The Emerging Function and Mechanism of ceRNAs in Cancer [PDF]

Trends in Genetics, 2016
Complex diseases, such as cancer, are often associated with aberrant gene expression at both the transcriptional and post-transcriptional level. Over the past several years, competing endogenous RNAs (ceRNAs) have emerged as an important class of post-transcriptional regulators that alter gene expression through a miRNA-mediated mechanism.
Yunfei, Wang, Jiakai, Hou, Dandan, He, Ming, Sun, Peng, Zhang, Yonghao, Yu, Yiwen, Chen   +6 more
openaire   +2 more sources

Transcription Profiling of a Revealed the Potential Molecular Mechanism of Governor Vessel Electroacupuncture for Spinal Cord Injury in Rats [PDF]

Neurospine, 2022
Objective This study aimed to identify differentially expressed genes (DEGs) by transcriptome analysis to elucidate a potential mechanism by which governor vessel electroacupuncture (GV-EA) promotes neuronal survival, axonal regeneration, and functional ...
Xingru Xiao, Qingwen Deng, Xiang Zeng, Bi-Qin Lai, Yuan-Huan Ma, Ge Li, Yuan-Shan Zeng, Ying Ding   +7 more
doaj   +1 more source

ceRNA analysis of SARS-CoV-2 [PDF]

Archives of Virology, 2020
Viral RNAs can perturb the miRNA regulatory network, competing with host RNAs as part of their infective process. An in silico competing endogenous RNA (ceRNA) analysis has been carried on SARS-CoV-2. The results suggest that, in humans, the decrease of microRNA activity caused by viral RNAs can lead to a perturbation of vesicle trafficking and the ...
openaire   +2 more sources

Extensive ceRNA–ceRNA interaction networks mediated by miRNAs regulate development in multiple rhesus tissues [PDF]

Nucleic Acids Research, 2016
Crosstalk between RNAs mediated by shared microRNAs (miRNAs) represents a novel layer of gene regulation, which plays important roles in development. In this study, we analyzed time series expression data for coding genes and long non-coding RNAs (lncRNAs) to identify thousands of interactions among competitive endogenous RNAs (ceRNAs) in four rhesus ...
Xu, Juan, Feng, Lin, Han, Zujing, Li, Yongsheng, Wu, Aiwei, Shao, Tingting, Ding, Na, Li, Lili, Deng, Wei, Di, Xuebing, Wang, Jian, Zhang, Lianfeng, Li, Xia, Zhang, Kaitai, Cheng, Shujun   +14 more
openaire   +2 more sources

Identification of circular RNA expression profiles in renal fibrosis induced by obstructive injury

Renal Failure, 2021
Introduction Advancing renal fibrosis is the common histopathological feature of chronic obstructive nephropathy, representing the final pathway of nearly all chronic and progressive nephropathies.
Jiangju Huang, Zhihao Zhang, Benquan Liu, Ying Gao, Jiayi Nie, Shihong Wen, Xiaohong Lai, Hua Liang   +7 more
doaj   +1 more source

Ethics in Robotics Research: CERNA Mission and Context [PDF]

IEEE Robotics & Automation Magazine, 2017
This article summarizes the recommendations concerning robotics as issued by the Commission for the Ethics of Research in Information Sciences and Technologies (CERNA), the French advisory commission for the ethics of information and communication technology (ICT) research.
Grinbaum, Alexei, Chatila, Raja, Devillers, Laurence, Ganascia, Jean-Gabriel, Tessier, Catherine, Dauchet, Max   +5 more
openaire   +1 more source

Perdarahan Saluran Cerna pada Anak dengan Penyakit Ginjal Tahap Akhir

Sari Pediatri, 2023
Penyakit ginjal tahap akhir (PGTA) adalah penyakit ginjal kronik (PGK) stadium 5 yang ditandai dengan laju filtrasi glomerulus (LFG) < 15 mL/menit/1,73m2 selama tiga bulan atau lebih, atau suatu kondisi dengan pasien memerlukan terapi pengganti ginjal ...
Beatrix Siregar, Eka Laksmi Hidayati, Sudung Oloan Pardede   +2 more
doaj   +1 more source

Variations in the Cuticular Chemical Profile of the Ant Ectatomma brunneum Smith, F. 1858 (Formicidae: Ectatomminae) Across Different Biomes in Brazil

Sociobiology
The insect cuticle is composed of chemical compounds that evolved to prevent desiccation and provide defense against pathogens. These compounds were subsequently co-opted for chemical communication and, in social insects, are crucial for nestmate ...
William Fernando Antonialli-Junior, Michele Castro de Paula-Silva, Erika Fernandes Neves, Sidnei Eduardo Lima-Junior, Luis Humberto da Cunha Andrade, Sandro Márcio Lima   +5 more
doaj   +1 more source