Results 21 to 30 of about 100,816 (310)
Frontiers in Immunology, 2023 Background Forkhead box M1 (FOXM1) is a member of the Forkhead box (Fox) transcription factor family. It regulates cell mitosis, cell proliferation, and genome stability.
Zi-Heng Xu +12 more
semanticscholar +1 more source
Competing endogenous RNA (ceRNA) networks in Parkinson's disease: A systematic review
Frontiers in Cellular Neuroscience, 2023 Parkinson's disease (PD) is a distinctive clinical syndrome with several causes and clinical manifestations. Aside from an infectious cause, PD is a rapidly developing neurological disorder with a global rise in frequency.
M. Asadi +10 more
semanticscholar +1 more source
Identification of a lncRNA/circRNA-miRNA-mRNA ceRNA Network in Alzheimer's Disease.
Journal of Integrative Neuroscience, 2023 BACKGROUND Alzheimer's disease (AD) occurs in the elderly and pre-elderly, characterized by decline of memory, cognitive dysfunction, impairment of learning capacity, and motor dysfunction.
Li-ning Su +3 more
semanticscholar +1 more source
The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer
Cell Death Discovery, 2022 Non-coding RNAs (ncRNAs), which occupy the vast majority of human transcripts are known for their inability to encode proteins. NcRNAs consist of a diverse range of RNA species, including long non-coding RNAs (lncRNAs), which have significant meaning for
Jichuan Xu +3 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 Background Tumor microenvironment (TME) plays important roles in different cancers. Our study aimed to identify molecules with significant prognostic values and construct a relevant Nomogram, immune model, competing endogenous RNA (ceRNA) in lung ...
Ting-Ting Liu +6 more
semanticscholar +1 more source
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1 [PDF]
Nature Communications, 2019 Circular RNAs (circRNAs) are identified as vital regulators in a variety of cancers. However, the role of circRNA in lung squamous cell carcinoma (LUSC) remains largely unknown.
Zhuoan Cheng +18 more
openalex +2 more sources
Role of exosomal competitive endogenous RNA (ceRNA) in diagnosis and treatment of malignant tumors
Bioengineered, 2022 Malignant tumors are a threat to human health, thus it is critical to better understand the mechanism of tumor occurrence and development and to find key therapeutic targets. Competitive endogenous RNA (ceRNA) is a type of RNA molecule that includes mRNA
Mingwen Mao +5 more
semanticscholar +1 more source
Construction of ceRNA regulatory networks for osteoporosis
Molecular Medicine Reports, 2023 Osteoporosis increases the risk of fracture. Improving the diagnosis and treatment of osteoporosis has clinical applications. The differentially expressed genes (DEcircRs, DEmRs, DEmiRs) of osteoporotic patients and controls were analyzed using the GEO database, and enrichment analysis of DEmRs was performed. circRNAs and mRNAs, which were predicted to
Chen, Hongtao +5 more
openaire +2 more sources
Translating ceRNA susceptibilities into correlation functions [PDF]
Biophysical Journal, 2017 Competition to bind microRNAs induces an effective positive crosstalk between their targets, therefore known as ‘competing endogenous RNAs’ or ceRNAs. While such an effect is known to play a significant role in specific situations, estimating its strength from data and, experimentally, in physiological conditions appears to be far from simple.
Araks Martirosyan +3 more
openaire +5 more sources
Frontiers in Immunology, 2022 Background Ulcerative colitis (UC) is an inflammatory disease of the intestinal mucosa, and its incidence is steadily increasing worldwide. Intestinal immune dysfunction has been identified as a central event in UC pathogenesis.
Mengmeng Xu +11 more
semanticscholar +1 more source