Results 31 to 40 of about 100,816 (310)

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

open access: yesNucleic Acids Res., 2013
Although microRNAs (miRNAs), other non-coding RNAs (ncRNAs) (e.g. lncRNAs, pseudogenes and circRNAs) and competing endogenous RNAs (ceRNAs) have been implicated in cell-fate determination and in various human diseases, surprisingly little is known about ...
Junhao Li   +4 more
semanticscholar   +1 more source

Identification of lncRNA/circRNA-miRNA-mRNA ceRNA Network as Biomarkers for Hepatocellular Carcinoma

open access: yesFrontiers in Genetics, 2022
Background: Hepatocellular carcinoma (HCC) accounts for the majority of liver cancer, with the incidence and mortality rates increasing every year. Despite the improvement of clinical management, substantial challenges remain due to its high recurrence ...
Shanshan Chen   +3 more
semanticscholar   +1 more source

lncRNA–miRNA–mRNA ceRNA Network Involved in Sheep Prolificacy: An Integrated Approach

open access: yesGenes, 2022
Understanding the molecular pattern of fertility is considered as an important step in breeding of different species, and despite the high importance of the fertility, little success has been achieved in dissecting the interactome basis of sheep ...
Masoumeh Sadeghi   +7 more
semanticscholar   +1 more source

ceRNAs: miRNA Target Mimic Mimics [PDF]

open access: yesCell, 2011
In a recent issue of Cell, four papers described regulatory interactions among messenger RNAs (mRNAs) that share target sequences for the same microRNAs (miRNAs) (Cesana et al., 2011; Karreth et al., 2011; Sumazin et al., 2011; Tay et al., 2011). The authors state that these mRNAs, dubbed “competing endogenous RNAs (ceRNAs),” define a new layer of ...
Ignacio Rubio-Somoza   +4 more
openaire   +3 more sources

lncRNA ACTA2-AS1 inhibits malignant phenotypes of gastric cancer cells

open access: yesOpen Medicine, 2022
Gastric cancer (GC) is one of the most common malignancies in digestive system. Accumulating evidence reveals the critical role of long noncoding RNAs (lncRNAs) in GC development.
Liu Zhiping   +5 more
doaj   +1 more source

Constraining sleptons at the LHC in a supersymmetric low-scale seesaw scenario [PDF]

open access: yes, 2017
We consider a scenario inspired by natural supersymmetry, where neutrino data is explained within a low-scale seesaw scenario. We extend the Minimal Supersymmetric Standard Model by adding light right-handed neutrinos and their superpartners, the R ...
Cerna-Velazco, Nhell   +3 more
core   +2 more sources

ceRNA crosstalk mediated by ncRNAs is a novel regulatory mechanism in fish sex determination and differentiation

open access: yesGenome Research, 2022
Competing endogenous RNAs (ceRNAs) are vital regulators of gene networks in mammals. The involvement of noncoding RNAs (ncRNAs) as ceRNA in genotypic sex determination (GSD) and environmental sex determination (ESD) in fish is unknown. The Chinese tongue
Lili Tang   +13 more
semanticscholar   +1 more source

ceRNA analysis of SARS-CoV-2 [PDF]

open access: yesArchives of Virology, 2020
Viral RNAs can perturb the miRNA regulatory network, competing with host RNAs as part of their infective process. An in silico competing endogenous RNA (ceRNA) analysis has been carried on SARS-CoV-2. The results suggest that, in humans, the decrease of microRNA activity caused by viral RNAs can lead to a perturbation of vesicle trafficking and the ...
openaire   +2 more sources

The mRNA related ceRNA–ceRNA landscape and significance across 20 major cancer types [PDF]

open access: yesNucleic Acids Research, 2015
Cross-talk between competitive endogenous RNAs (ceRNAs) through shared miRNAs represents a novel layer of gene regulation that plays important roles in the physiology and development of cancers. However, a global view of their system-level properties across various types of cancers is still unknown.
Tao Pan   +9 more
openaire   +2 more sources

Gene signature to predict prognostic survival of hepatocellular carcinoma

open access: yesOpen Medicine, 2022
Hepatocellular carcinoma (HCC) has a high incidence and poor prognosis and is the second most fatal cancer, and certain HCC patients also show high heterogeneity. This study developed a prognostic model for predicting clinical outcomes of HCC.
Li Li, Cao Yundi, Fan YingRui, Li Rong
doaj   +1 more source

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