Results 61 to 70 of about 28,293 (248)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
Identifying survival-associated ceRNA clusters in cholangiocarcinoma
Oncology Reports, 2016 Competing endogenous RNAs (ceRNAs) represent a novel layer regulations of long non-coding RNAs (lncRNAs) and genes that play important roles in cancer pathogenesis by binding microRNAs (miRNAs). However, the competition mechanism of ceRNAs in cholangiocarcinoma (CHOL) is not fully understood.
Ming, Wan +11 more
openaire +3 more sources
Cell Proliferation, EarlyView.Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao +8 more
wiley +1 more source
Probiotik Pada Gangguan Saluran Cerna Fungsional [PDF]
Sari Pediatri, 2018 Probiotik memiliki kemampuan untuk memengaruhi komposisi mikroflora saluran cerna. Ketika dikonsumsi dalam jumlah adekuat, probiotik memiliki efek positif terhadap kesehatan pejamu. Terdapat beberapa penelitian yang menilai efek terapeutik probiotik terhadap berbagai macam penyakit, termasuk gangguan saluran cerna fungsional pada anak. Gangguan saluran
Valerie Andrea, Badriul Hegar
openaire +2 more sources
Whole-transcriptome RNA sequencing reveals global expression dynamics and ceRNA regulatory networks related to hair follicle development and melanogenesis in goats [PDF]
Animal BioscienceObjective Domestic animals, fur is a product of long-term selection by humans and the natural environment. It is generally used to distinguish between different breeds.
Junyin Zhao +4 more
doaj +1 more source
The Incarnational Aesthetic of David Brown☆
International Journal of Systematic Theology, EarlyView.Abstract The notion of incarnation has historically been a prominent concept for the acceptance of images and the interpretation of art within Christianity. A contemporary proponent of this line of reasoning about the theological potential of art is David Brown, who builds his theology of culture on the doctrine of incarnation. This article presents an
Filip Taufer
wiley +1 more source
Expression profile of circular RNAs in type 2 diabetes mellitus patients with retinopathy
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims/Introduction Diabetic retinopathy (DR) is a prevalent chronic complication of type 2 diabetes mellitus (T2DM), contributing significantly to vision impairment. Circular RNAs (circRNAs) have emerged as key regulators in the pathogenesis of DR.
Wencheng An +9 more
wiley +1 more source
Comprehensive Diagnostics of Diabetic Nephropathy by Transcriptome RNA Sequencing
Diabetes, Metabolic Syndrome and Obesity, 2022 Lei Lei,1 Yihua Bai,1 Yang Fan,1 Yaling Li,1 Hongying Jiang,1 Jiaping Wang2 1Department of Nephrology, The Second Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, People’s Republic of China; 2Department of Radiology, The Second ...
Lei L +5 more
doaj
Comprehensive analysis of a cuproptosis-related ceRNA network implicates a potential endocrine therapy resistance mechanism in ER-positive breast cancer [PDF]
, 2023 Dongni Zhang +5 more
openalex +1 more source