Results 121 to 130 of about 3,332 (192)

CES1 Gene [PDF]

, 2020
openaire   +1 more source

Impaired chaperone-mediated autophagy leads to abnormal SORT1 (sortilin 1) turnover and CES1-dependent triglyceride hydrolysis

SORT1 (sortilin 1), a member of the the Vps10 (vacuolar protein sorting 10) family, is involved in hepatic lipid metabolism by regulating very low-density lipoprotein (VLDL) secretion and facilitating the lysosomal degradation of CES1 (carboxylesterase 1)
Lee, Wonseok, Han, Byung Woo, Mun, Yewon, Yu, Jihyeon, Park, Cheon Jun, Choi, You-Jin, Nam, Yoon Ah, Hyun, Ji Ye, Lee, Byung-Hoon, Yun, Sung Ho   +9 more
core   +1 more source

CES1 wt Allele [PDF]

, 2020
openaire   +1 more source

Carboxylesterase 1 (CES1; hCE1) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Role of CES1 and ABCB1 Genetic Polymorphisms on Functional Response to Dabigatran in Patients with Atrial Fibrillation [PDF]

Background: Dabigatran etexilate is a pro-drug hydrolyzed into dabigatran by carboxylesterases (CES) and is a substrate of the P-Glycoprotein encoded by the adenosine-triphosphate-binding cassette sub-family B member (ABCB)1 genes.
Antonucci, Ivana, Stuppia, Liborio, Mirco Zucchelli, Shail, Tarek, Valentina Zanotti, Giacomini, Luca, Renda, Giulia, Raffaella Auciello, Iezzi, Lorena, Roberta Rolla, Auciello, Raffaella, Luca Cumitini, Sara Sacchetti, Ilaria Angilletta, Dianzani, Umberto, Luca Giacomini, Ivana Antonucci, Zanotti, Valentina, Umberto Dianzani, Rolla, Roberta, Sabina Gallina, Sacchetti, Sara, Zucchelli, Mirco, Melissa Foglietta, Angilletta, Ilaria, Patti, Giuseppe, Giulia Renda, Foglietta, Melissa, Mara Giordano, Giordano, Mara, Liborio Stuppia, Gallina, Sabina, Giuseppe Patti, Cumitini, Luca, Tarek Shail, Lorena Iezzi   +35 more
core   +1 more source

Identification of New Fluorescein-Based Chemical Tools for Studying Human Carboxylesterase 1 (CES1)

This thesis focuses on the significance of subcellular location-specific activity of hydrolases, exploring their implications for drug-drug interactions (DDIs) and sequence polymorphisms in drug metabolism.
Adusah, Emmanuel
core  

Metastatik meme kanserli hastalarda CES1 gen polimorfizmlerinin görülme sıklıkları ve capecitabine kullananlarda ilaç yanıtına etkilerinin retrospektif olarak değerlendirilmesi

, 2008
Meme kanseri dünyada sık görülen ve kadın ölümlerinden en fazla sorumlu olan multifaktoriyel bir hastalıktır. Nedenleri arasında üremeyle ilgili etkenler, hormonal etkenler, genetik etkenler ve sosyo-ekonomik durum gibi faktörler yer almaktadır.
Aygüneş, Duygu Döndü
core  

The impact of ABCB1 (rs1045642 and rs4148738) and CES1 (rs2244613) gene polymorphisms on dabigatran equilibrium peak concentration in patients after total knee arthroplasty [Corrigendum]

Pharmacogenomics and Personalized Medicine, 2018
Sychev DA, Levanov AN, Shelekhova TV, Bochkov PO, Denisenko NP, Ryzhikova KA, Mirzaev KB, Grishina EA, Gavrilov MA, Ramenskaya GV, Kozlov AV, Bogoslovsky T. Pharmgenomics Pers Med. 2018;11:127-137. In this paper, the CC genotypes of CES1 (rs2244613)
Sychev DA, Levanov AN, Shelekhova TV, Bochkov PO, Denisenko NP, Ryzhikova KA, Mirzaev KB, Grishina EA, Gavrilov MA, Ramenskaya GV, Kozlov AV, Bogoslovsky T   +11 more
doaj  

The interplay between CES1 gene polymorphisms and environmental exposures in chemotherapy toxicity in breast cancer: CES1 variants and environment in chemo toxicity

Breast cancer remains one of the most prevalent malignancies worldwide, with chemotherapy serving as a cornerstone of treatment despite its substantial toxicity risks.
Aygunes Jafari, Duygu, Sezgin, Canfeza, Kosova, Buket   +2 more
core   +1 more source

Triazine Thiols Decrease Apolipoprotein B Secretion From Hepatocytes Through Inhibition of Human Carboxylesterase 1. [PDF]

Cell Mol Gastroenterol Hepatol
Blaszkiewicz J, Jiang YL, Liu JT, Martinez-Morant C, Dearth T, van Altena C, Lamprecht MP, Kappler C, Lee MH, Bethard JR, Ball LE, Duncan SA.   +11 more
europepmc   +1 more source