Results 91 to 100 of about 15,331 (173)

Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes

Journal of Lipid Research, 2004
Previous reports attributed cholesteryl ester transfer protein (CETP)-mediated HDL cholesteryl ester (CE) selective uptake to the CETP-mediated transfer of CE from HDL to newly secreted apolipoprotein B-containing lipoproteins, which are then ...
Gerard Vassiliou, Ruth McPherson
doaj   +1 more source

Atomistic MD simulation reveals the mechanism by which CETP penetrates into HDL enabling lipid transfer from HDL to CETP

Journal of Lipid Research, 2015
Inhibition of cholesterol ester transfer protein (CETP), a protein mediating transfer of neutral lipids between lipoproteins, has been proposed as a means to elevate atheroprotective HDL subpopulations and thereby reduce atherosclerosis.
Geraldine Cilpa-Karhu, Matti Jauhiainen, Marja-Liisa Riekkola   +2 more
doaj   +1 more source

Lack of stimulation of cholesteryl ester transfer protein by cholesterol in the presence of a high-fat diet

Journal of Lipid Research, 2005
Cholesteryl ester transfer protein (CETP) is a key protein involved in the reverse cholesterol transport pathway. The regulation of CETP by dietary fats is not clearly understood.
Sukhinder Kaur Cheema, Alka Agarwal-Mawal, Cathy M. Murray, Stephanie Tucker   +3 more
doaj   +1 more source

Effect of xanthohumol on serum cholesterol and CETP activity.

, 2012
Serum HDL-C concentration in the control group (closed circle), xanthohumol group (opened circle) and Chow group (closed triangle) of CETP-Tg mice (A), and in the control group (closed square) and xanthohumol group (opened square) of wild-type mice (B ...
Tatsuro Shigyo (119749), Shuichi Segawa (119742), Naoyuki Kobayashi (119748), Yimin (119741), Hiroshi Hirata (119738), Hitoshi Chiba (119750), Moeko Ozaki (119745)   +6 more
core   +1 more source

Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver

Lipids in Health and Disease, 2009
Background CETP is a plasma protein that modulates atherosclerosis risk through its HDL-cholesterol reducing action. The aim of this work was to examine the effect of the PPARα agonist, ciprofibrate, on the CETP gene expression, in the presence and ...
Berti Jairo A, Casquero Andrea C, Patrício Patrícia R, Bighetti Eliete JB, Oliveira Helena CF   +4 more
doaj   +1 more source

Interaction of CETP with core lipids.

, 2012
A) Snapshots from the coarse-grained simulations CG3 (left) and CG3-90POPC (right). The upper snapshots show side views and the lower ones top views of CETP bound to a lipid droplet. In the latter, the hydrophobic patch under CETP is clearly visible. The
Timo Vuorela (188185), Petri T. Kovanen (188189), Artturi Koivuniemi (188184), Marja T. Hyvönen (188196), Ilpo Vattulainen (188193)   +4 more
core   +1 more source

Familial cholesteryl ester transfer protein deficiency is associated with triglyceride-rich low density lipoproteins containing cholesteryl esters of probable intracellular origin.

Journal of Lipid Research, 1991
The net transfer of core lipids between lipoproteins is facilitated by cholesteryl ester transfer protein (CETP). We have recently documented CETP deficiency in a family with hyperalphalipoproteinemia, due to a CETP gene splicing defect.
CL Bisgaier, MV Siebenkas, ML Brown, A Inazu, J Koizumi, H Mabuchi, AR Tall   +6 more
doaj   +1 more source

Dynamical properties of CETP.

, 2014
A) Residual RMS fluctuations for short 20 ns and long 200 ns simulations. The peaks indicate the regions of CETP that fluctuate the most over the course of simulations.
Artturi Koivuniemi (188184), Matti Javanainen (621722), Tarja Äijänen (663832), Tomasz Rog (1568779), Ilpo Vattulainen (188193), Sami Rissanen (663833)   +5 more
core   +1 more source

The role of CETP and HDL metabolism in cardiac disease [PDF]

, 2008
This thesis describes the effects of plasma CETP levels and common CETP polymorphisms, in their relation to HDL metabolism and triglycerides, on cardiac risk in a general western population.
Borggreve, Susanna Etje
core   +4 more sources

Apolipoprotein CI overexpression is not a relevant strategy to block cholesteryl ester transfer protein (CETP) activity in CETP transgenic mice

, 2005
ApoCI (apolipoprotein CI) is a potent inhibitor of plasma CETP [CE (cholesteryl ester) transfer protein]. The relevance of apoCI overexpression as a method for CETP blockade in vivo was addressed in the present study in CETPTg/apoCITg mice (mice ...
Duverneuil, L., Zak, Z., Pais De Barros, J.P., Dumont, L., Deckert, V., Lagrost, L., Havekes, L.M., Masson, D., Gautier, T., Jong, M.C., Bataille, A., Jiang, X.C., Guern, N. Le   +12 more
core