Results 81 to 90 of about 15,331 (173)

CETP gene variation:relation to lipid parameters and cardiovascular risk

, 2004
PURPOSE OF REVIEW: Over the past decade lowering of low-density lipoprotein-cholesterol levels has been established as the foundation for preventing coronary artery disease, but substantial additional risk reduction remains to be gained by modifying risk
Hovingh, G Kees, Jukema, J Wouter, Kuivenhoven, Jan-Albert, van Tol, Arie, Kastelein, John JP, Boekholdt, S Matthijs   +5 more
core   +2 more sources

Cholesteryl ester transfer protein alters liver and plasma triglyceride metabolism through two liver networks in female mice[S]

Journal of Lipid Research, 2016
Elevated plasma TGs increase risk of cardiovascular disease in women. Estrogen treatment raises plasma TGs in women, but molecular mechanisms remain poorly understood.
Brian T. Palmisano, Thao D. Le, Lin Zhu, Yoon Kwang Lee, John M. Stafford   +4 more
doaj   +1 more source

The hypertension peril: lessons from CETP inhibitors

, 2009
Pharmacologic inhibitors of the cholesteryl ester transfer protein (CETP) are capable of increasing HDL cholesterol by 50% to 100% in humans. Despite intriguing antiatherogenic effects of CETP inhibition in animal models of atherosclerosis, the ...
Ruschitzka, F, Hermann, M
core   +1 more source

Overexpression of full-length cholesteryl ester transfer protein in SW872 cells reduces lipid accumulation

Journal of Lipid Research, 2015
Cells produce two cholesteryl ester transfer protein (CETP) isoforms, full-length and a shorter variant produced by alternative splicing. Blocking synthesis of both isoforms disrupts lipid metabolism and storage.
Lahoucine Izem, Diane J. Greene, Katarzyna Bialkowska, Richard E. Morton   +3 more
doaj   +1 more source

Forest plots depicting the effect of CETP inhibitors on apolipoproteins (grouped by different CETP inhibitors) A: apoAI; B: apoB 100.

, 2013
Forest plots depicting the effect of CETP inhibitors on apolipoproteins (grouped by different CETP inhibitors) A: apoAI; B: apoB 100.
Liang Zhou (85586), Hao Luo (454719), Faying Zhou (477418), Caiyu Chen (477419), Chuanwei Li (477417), Yafei Li (184478), Ling Liu (143030), Chunyu Zeng (391669), Jing Cai (112307), Wen Zhang (7555), Zhangxue Hu (477421), Fang Pei (477420)   +11 more
core   +1 more source

Apolipoprotein E enhances lipid exchange between lipoproteins mediated by cholesteryl ester transfer protein.

Journal of Lipid Research, 1993
The direct effect of apolipoprotein (apo) E on cholesteryl ester transfer protein (CETP) activity was studied using lipoproteins from a subject with apoE deficiency (Atherosclerosis. 1991. 88: 15-20) as a model system.
M Kinoshita, H Arai, M Fukasawa, T Watanabe, K Tsukamoto, Y Hashimoto, K Inoue, K Kurokawa, T Teramoto   +8 more
doaj   +1 more source

eNOS activation by HDL is impaired in genetic CETP deficiency [PDF]

, 2014
Mutations in the CETP gene resulting in defective CETP activity have been shown to cause remarkable elevations of plasma HDL-C levels, with the accumulation in plasma of large, buoyant HDL particles enriched in apolipoprotein E.
Hovingh, G Kees, Peter Nilsson, Angelo B Cefalù, Franceschini, G, Hovingh, GK, AVERNA, Maurizio, Nilsson, P, Veglia, Fabrizio, Maurizio Averna, G. Franceschini, Cefalu, Angelo B., CEFALU', Angelo Baldassare, Ossoli, Alice, Franceschini, Guido, S. Pozzi, Kuivenhoven, Jan Albert, G Kees Hovingh, M. Averna, Silvia Pozzi, Kuivenhoven, JA, Laura Calabresi, Jan Albert Kuivenhoven, Gomaraschi, M, Calabresi, Laura, Guido Franceschini, Hovingh, G. Kees, Monica Gomaraschi, L. Calabresi, Nilsson, Peter, A. Ossoli, Pozzi, Silvia, G. . K. Hovingh, Ossoli, A, F. Veglia, Gomaraschi, Monica, P. Nilsson, Veglia, F, J. A. Kuivenhoven, A. B. Cefalù, Alice Ossoli, M. Gomaraschi, Pozzi, S, Calabresi, L., Cefalù, Angelo B, Fabrizio Veglia   +44 more
core   +2 more sources

Relationship between concentration of CETP protein and lipid transfer activity.

, 2023
Increasing amounts of recombinant CETP (SRP6177; Sigma-Aldrich, St. Louis, MO) in a total volume of 1 μL was used to assess the correlation of lipid transfer activity and CETP protein concentration using the CETP Activity Assay Kit II (ab196995; Abcam ...
Åsa Schawlann Ølnes (17537519), Marianne Teigen (17537522), Trond P. Leren (14223497), Jon K. Laerdahl (7840751), Katrine Bjune (6858293), Thea Bismo Strøm (17537525)   +5 more
core   +1 more source

Reduction in the concentration and activity of plasma cholesteryl ester transfer protein by alcohol.

Journal of Lipid Research, 1992
Plasma cholesteryl esters, synthesized within high density lipoproteins (HDL), may be transferred from HDL particles to other lipoproteins by plasma cholesteryl ester transfer protein (CETP).
M Hannuksela, YL Marcel, YA Kesäniemi, MJ Savolainen   +3 more
doaj   +1 more source

A Novel Mutation in the Human Plasma Cholesteryl Ester Transfer Protein (CETP) Gene Leading to CETP-Deficiency in a Nova Scotian Patient: A Review of CETP Deficiency

, 1998
Human Cholesteryl Ester Transfer Protein (CETP) is a 476-residue hydrophobic plasma glycoprotein which catalyzes the hetero-exchange and net mass transfer of cholesteryl esters and triacylglycerols between plasma High Density Lipoprotein (HDL) and Very ...
Dolphin, Peter J.
core   +1 more source