Results 61 to 70 of about 15,331 (173)

Heterogeneity at the CETP gene locus. Influence on plasma CETP concentrations and HDL cholesterol levels.

, 1997
This study was designed to investigate the association(s) between heterogeneity at the cholesteryl ester transfer protein (CETP) gene locus, CETP plasma concentrations, and HDL cholesterol levels.
Jolanda M.A. Boer, de Knijff, P., P. Haydn Pritchard, Kuivenhoven, J.A., Harold A. Smalheer, Boer, J. M., Boer, J M, Kastelein, J.J.P., John J.P. Kastelein, Botma, G J, Peter de Knijff, Kuivenhoven, J A, Pritchard, P H, Knijff, P., de, Botma, G. J., Kuivenhoven, J. A., Boer, J.M.A., Gert-Jan Botma, Pritchard, P. H., Jan Albert Kuivenhoven, Smalheer, H.A., Pritchard, P.H., Seidell, J. C., Kastelein, J J, Seidell, J C; id_orcid, Seidell, J C, Kastelein, J.J., de Knijff, P, Smalheer, H. A., Seidell, J.C., Kastelein, J. J., Jaap C. Seidell, Smalheer, H A, Botma, G.J.   +33 more
core   +1 more source

Gender effects on the distribution of the cholesteryl ester transfer protein in apolipoprotein A-I-defined lipoprotein subpopulations.

Journal of Lipid Research, 1994
Two subpopulations of apolipoprotein A-I-containing lipoproteins, those containing only apoA-I (LpA-I) and those containing both apoA-I and apoA-II (LpA-I/A-II), were isolated by immunoaffinity chromatography of plasma from 44 subjects, comprising four ...
P Moulin, M C Cheung, C Bruce, S Zhong, T Cocke, H Richardson, A R Tall   +6 more
doaj   +1 more source

The Shared IL‐12/IL‐35 p35 Subunit Is Associated With Heightened Atherogenic Risk in African Patients With Type 2 Diabetes

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Hyperglycaemia‐driven metabolic dysfunction is associated with elevated circulating levels of the shared IL‐12/IL‐35 p35 subunit and an adverse atherogenic phenotype. These findings identify p35 as a promising biomarker of cardiovascular risk in patients with type 2 diabetes.
Tawanda M. Nyambuya, Edwig Shingenge, Fransina Ndevahoma, Bongani B. Nkambule   +3 more
wiley   +1 more source

Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant‐Based Therapies: A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation,
Nawfal Hasan Siam, Umme Halima Mithila, Sadia Alam Tisha, Hridoy Saha, Ayesha Binte Mahbub, Farhan Nizam, Johirul Islam, Noushin Tabasumma, Md. Mazharul Islam Chowdhury   +8 more
wiley   +1 more source

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C− Kupffer Cell Subsets

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundLipopolysaccharide (LPS) decreases hepatic CETP (cholesteryl ester transfer protein) expression albeit that the underlying mechanism is disputed. We recently showed that plasma CETP is mainly derived from Kupffer cells (KCs).
Sam J. L. van der Tuin, Zhuang Li, Jimmy F. P. Berbée, Inge Verkouter, Linda E. Ringnalda, Annette E. Neele, Jan B. van Klinken, Sander S. Rensen, Jingyuan Fu, Menno P. J. de Winther, Albert K. Groen, Patrick C. N. Rensen, Ko Willems van Dijk, Yanan Wang   +13 more
doaj   +1 more source

A uterine‐centric view of reproductive senescence: Genetic insights into late‐life performance in laying hens

iMetaOmics, Volume 3, Issue 3, September 2026.
This study identifies uterus weight as a heritable (h2 = 0.45) intermediate phenotype that independently associates with late‐life egg production and eggshell quality in aged laying hens. Genome‐wide association study (GWAS) reveals a genome‐wide significant locus on chromosome 3 and suggestive loci on chromosome 11 for uterus weight, mediation ...
Junnan Zhang, Mingyue Gao, Ronglang Cai, Xinwei Jiang, Boxuan Zhang, Zhaojie Li, Ning Yang, Congjiao Sun   +7 more
wiley   +1 more source

Cholesteryl ester transfer protein expression is down-regulated in hyperinsulinemic transgenic mice

Journal of Lipid Research, 2003
Cholesteryl ester transfer protein (CETP) mediates cholesteryl ester (CE) and triglyceride redistribution among plasma lipoproteins. In this work, we investigated whether varying levels of insulin regulate the CETP expression in vivo. Insulin deficiency [
J.A. Berti, A.C. Casquero, P.R. Patrício, E.J.B. Bighetti, E.M. Carneiro, A.C. Boschero, H.C.F. Oliveira   +6 more
doaj   +1 more source

Type 2 Diabetes Mellitus Modifies the Prognostic Value of LDL Particle Size in Statin‐treated Patients With Coronary Artery Disease: A Large‐scale Cohort Study

MedComm, Volume 7, Issue 9, September 2026.
The LDL‐C/ApoB ratio, a marker of LDL size, showed significant prognostic value in statin‐treated CAD patients depending on diabetes status. A higher ratio was linked to lower cardiovascular risk only in patients with type 2 diabetes, suggesting it may be a superior biomarker for risk stratification beyond conventional lipids in this high‐risk group ...
Xiaohui Bian, Jining He, Chenxi Song, Rui Zhang, Sheng Yuan, Guofeng Gao, Kefei Dou   +6 more
wiley   +1 more source

Viability of developing CETP inhibitors

, 2008
The recent failure of a major inhibitor of the cholesterol ester transfer protein (CETP), in trials on high-risk coronary patients, indicated that potentially this therapeutic target might not be a viable one.
Cesare R. Sirtori, G. Mombelli, Giuliana Mombelli, C.R. Sirtori   +3 more
core   +1 more source

Evolutionary conservation of CETP with the 24 CETP variants indicated.

, 2023
Multiple sequence alignment of 24 CETP genes from different species. Protein sequences that are homologous to human CETP were obtained from the NCBI RefSeq database resources [1] by employing standard BLAST sequence searching [2].
Åsa Schawlann Ølnes (17537519), Marianne Teigen (17537522), Trond P. Leren (14223497), Jon K. Laerdahl (7840751), Katrine Bjune (6858293), Thea Bismo Strøm (17537525)   +5 more
core   +1 more source