Results 41 to 50 of about 15,331 (173)

Novel Role of CETP in Macrophages: Reduction of Mitochondrial Oxidants Production and Modulation of Cell Immune-Metabolic Profile

Antioxidants, 2022
Plasma cholesteryl ester transfer protein (CETP) activity diminishes HDL-cholesterol levels and thus may increase atherosclerosis risk. Experimental evidence suggests CETP may also exhibit anti-inflammatory properties, but local tissue-specific functions
Gabriel G. Dorighello, Leandro H. P. Assis, Thiago Rentz, Joseane Morari, Monique F. M. Santana, Marisa Passarelli, Neale D. Ridgway, Anibal E. Vercesi, Helena C. F. Oliveira   +8 more
doaj   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

A Comparison of Screening Methods for Assessing Legacy Wells Within CO2 Storage Licences: Application to Offshore Norway

Greenhouse Gases: Science and Technology, EarlyView.
ABSTRACT Legacy wells represent a critical consideration for offshore CO2 storage projects, as they may provide potential pathways for fluid or gas migration if poorly constructed, undocumented or inadequately abandoned. Systematically assessing large numbers of legacy wells remains challenging due to heterogeneous data availability and the diversity ...
Benjamin Emmel, Ole‐Andre Roli, Maxence Vergne, Guilhem Hauguel, Bastien Dupuy   +4 more
wiley   +1 more source

cetp/exclosures: First release

, 2016
<p>All the data, metadata and R code necessary to re-create the analyses in Paine, Beck and Terborgh (2016) "How mammalian predation contributes to tropical tree community structure".
C. E. Timothy Paine
core   +1 more source

Measurement of plasma anti-CETP titers and CETP activity in rabbits immunized with Fc-CETP₆ (experiment 1).

, 2014
(A) Plasma antibody titers against CETP. Plasma samples were collected as described in material and methods (Control group n = 7; Fc-CETP6 group n = 8) and diluted 2000-fold and the anti-CETP titer measured by ELISA. (B) Plasma CETP activity. Plasma CETP
Yi-Wei Liaw (671344), Shin Nieh (183317), Jacqueline Whang-Peng (30221), Shao-Chun Lu (671349), Chau-Jong Wang (54968), Chi-Yu Lin (671345), Leroy F. Liu (173706), Chia-Po Lin (671348), Yu-Sheng Lai (671346), Tzu-Chung Yang (671347), Jaulang Hwang (173712)   +10 more
core   +1 more source

Lipid transfer activities compared to amounts of CETP protein in the media for the different CETP variants.

, 2023
(A) The relationship between the amounts of CETP in the media and the corresponding lipid transfer activities is shown. The levels of protein secreted for the 20 CETP variants from Fig 1B have been plotted against the respective lipid transfer activities
Åsa Schawlann Ølnes (17537519), Marianne Teigen (17537522), Trond P. Leren (14223497), Jon K. Laerdahl (7840751), Katrine Bjune (6858293), Thea Bismo Strøm (17537525)   +5 more
core   +1 more source

Structure-function relationships of human cholesteryl ester transfer protein: analysis using monoclonal antibodies.

Journal of Lipid Research, 1996
Cholesteryl ester transfer protein (CETP), a 476 amino acid glycoprotein, mediates cholesteryl ester (CE), triglyceride, and phospholipid transfer among plasma lipoproteins.
P Roy, R MacKenzie, T Hirama, X C Jiang, P Kussie, A Tall, E Rassart, R Milne   +7 more
doaj   +1 more source

Different blood lipid profiles and their role in cardiometabolic disease progression: A comparative study between an East Asian and European Large Prospective Cohorts

VIEW, EarlyView.
In this study, we analyzed data from the Kailuan study in China (N = 95,711) and the UK Biobank (N = 388,317), comprising adults free of CMDs at baseline. The results demonstrated distinct, population‐specific patterns regarding how blood lipids influence the transition from a healthy state to incident CMDs and subsequently to CMM.
Lili Huang, Zhe Huang, Fandi Mo, Xinming Xu, Yuchong Zhang, Xinqiang Ma, Tingting Geng, Chengkai Hu, Shiyi Li, Genmao Cao, Hanji Fang, Shouji Qiu, Zhicheng Zhang, Sun Liang, Xiang Gao, Shouling Wu, Lixin Wang   +16 more
wiley   +1 more source

Contact Activation Is Alleviated by Testosterone Replacement Therapy in Klinefelter Syndrome: Evidence of Hormonal and Metabolic Modulation

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang, Claus H. Gravholt, Anne Skakkebæk, Anna‐Marie Bloch Münster, Yaseelan Palarasah   +4 more
wiley   +1 more source

The role of CETP inhibition in dyslipidemia [PDF]

, 2007
Cholesteryl ester transfer protein (CETP) inhibitors are currently being investigated because of their ability to increase high-density lipoprotein cholesterol levels.
Karim El Harchaoui, Erik S. G. Stroes, El Harchaoui, Karim, Wim A. van der Steeg, John J. P. Kastelein, van der Steeg, Wim A., Stroes, Erik S. G., Kastelein, John J. P.   +7 more
core   +1 more source