Results 91 to 100 of about 23,420 (253)

The importance of gene polymorphism in familial inheritance of endometriosis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik, Candan Eker, Berivan Guzelbag, Ercan Bastu, Tuba Gunel   +4 more
wiley   +1 more source

Sequencing metrics of urine cfDNA for all patients.

, 2021
cfDNA, cell-free DNA. (XLSX)
Jeffrey J. Szymanski (11361789), Brian C. Baumann (7431935), Faridi Qaium (11361786), Melissa A. Reimers (11361792), Vivek K. Arora (5702474), Ramandeep K. Babbra (11361765), Wenjia Feng (11361768), Katherine Dienstbach (11361777), Eric H. Kim (4060258), Zachary L. Smith (11361795), Pradeep S. Chauhan (2618257), Kevin Chen (264284), Li Ding (16240), Armaan Nallicheri (11361774), Nadja Pejovic (11361771), Lenon Maguire (11361783), Dengfeng Cao (6382949), Andrew Atkocius (11361780), Aadel A. Chaudhuri (11361798), Peter K. Harris (2312653)   +19 more
core   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

Measurement of 0.5% cfDNA.

, 2023
Measurements shown of 0.5% mimicking dd-cfDNA, as constituted by different absolute values of 100, 200, and 300 copies per reaction spiked into backgrounds of 20,000; 30,000; and 60,000 copies per reaction, respectively.
Leif Kofoed Nielsen (14675947), Frederik Banch Clausen (11657806), Kristine Mathilde Clara Lund Jørgensen (14675941), Grethe Risum Krog (14675950), Lasse Witt Wardil (14675944)   +4 more
core   +1 more source

Integrating NIPT and ultrasound for detecting fetal aneuploidies and abnormalities

Journal of Perinatal Medicine
The advent of non-invasive prenatal testing (NIPT) utilizing cell-free fetal DNA (cfDNA) has transformed the landscape of early chromosomal anomaly detection.
Andonotopo Wiku, Bachnas Muhammad Adrianes, Pribadi Adhi, Alamsyah Azis Muhammad, Aldika Akbar Muhammad Ilham, Ernawati, Hariyasa Sanjaya I Nyoman, Putra Wiradnyana Anak Agung Gede, Aldiansyah Dudy, Dewantiningrum Julian, Adi Pramono Mochammad Besari, Wantania John, Sulistyowati Sri, Stanojevic Milan, Kurjak Asim   +14 more
doaj   +1 more source

Exploring sex differences in blood-based biomarkers following exhaustive exercise using bioinformatics analysis

Biology of Sport
This study examined the acute effects of exercise testing on immunology markers, established blood-based biomarkers, and questionnaires in endurance athletes, with a focus on biological sex differences. Twenty-four healthy endurance-trained participants (
Julia C. Blumkaitis, Natalia Nunes, Tilmann Strepp, Aleksandar Tomaskovic, Mario Wenger, Hannah Widauer, Lorenz Aglas, Perikles Simon, Thomas Leonhard Stöggl, Nils Haller   +9 more
doaj   +1 more source

In Silico Fragment Size Selection for Enhanced Fetal Fraction and Abnormality Origin Discernment Using Pair‐End Sequencing of Maternal Plasma DNA

Journal of Clinical Laboratory Analysis, EarlyView.
This study presents a new bioinformatics pipeline for noninvasive prenatal testing (NIPT) that filters DNA fragments to significantly improve the fetal DNA fraction. This enhanced method successfully analyzed samples previously rejected for low fetal fraction and could distinguish between fetal and maternal chromosomal abnormalities.
Lihui Yang, Jiutong Zhang, Ji Zhang, Qiujie Jin, Yating Wang, Qiuhua Wu, Fengrui Shi, Rui Wang, Yunping Liu, Na Cai, Xiaobin Wang, Rong Qiang   +11 more
wiley   +1 more source

Application of Cell‐Free DNA Barcode‐Enabled Single‐Molecule Test for Non‐Invasive Prenatal Testing of α‐Thalassemia and β‐Thalassemia

Journal of Clinical Laboratory Analysis, EarlyView.
We evaluated the cfBEST assay for non‐invasive prenatal testing of α‐ and β‐thalassemia in 72 families. The assay correctly identified 88 of 93 fetal alleles, achieving an overall accuracy of 94.6%, a sensitivity of 94%, and a specificity of 95.35%, with 100% concordance with postnatal follow‐up.
Qin Liu, Na Ma, Wanglan Tang, Qianting Chen, Deguo Tang, Chunyan Zeng, Xiaofeng Wang, Hui Xi   +7 more
wiley   +1 more source

The utility of cfDNA in TGCT patient management: a systematic review

, 2022
BACKGROUND: Testicular germ cell tumors (TGCTs) are the most common young male malignancy with a steadily rising incidence. Standard clinical practice is radical orchidectomy of suspicious lumps followed by histopathological diagnosis and tumor subtyping.
Krasic, Jure, Skara, Lucija, Ulamec, Monika, Kulis, Tomislav, Katušić Bojanac, Ana, Jezek, Davor, Sincic, Nino, Bojanac, Ana Katusic   +7 more
core   +1 more source

Dynamic Prognostic Nutritional Index With Circulating Tumor DNA Predicts Survival in Localized Pancreatic Ductal Adenocarcinoma

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives To evaluate the prognostic significance of baseline and longitudinal changes in prognostic nutritional index (PNI) in localized pancreatic ductal adenocarcinoma (PDAC) and to assess the complementary prognostic value of PNI with tumor burden measured by circulating tumor DNA (ctDNA).
Alex Horowitz, Claire Shen, Dominic J. Vitello, Madison Cox, Amy Wells, Krishay Sridalla, David J. Bentrem, Qiang Zhang, Ishan Roy, Akhil Chawla   +9 more
wiley   +1 more source