Results 101 to 110 of about 19,806 (216)
cfDNA monitoring is feasible in SCLC [PDF]
Nature Reviews Clinical Oncology, 2019 openaire +2 more sources
Advances in cfDNA research for pregnancy-related diseases
Frontiers in Cell and Developmental BiologyCirculating cell-free DNA (cfDNA) comprises extracellular DNA fragments released into bodily fluids through cellular processes such as apoptosis, necrosis, and active secretion. Alterations in cfDNA concentration, fragmentation patterns, and molecular characteristics under physiological and pathological conditions, including pregnancy-related disorders,
Yimei Meng +5 more
openaire +3 more sources
International Journal of Cancer, Volume 159, Issue 8, Page 1873-1883, 15 October 2026.ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers due to its asymptomatic progression, late‐stage diagnosis, and treatment resistance. Efforts in early detection have centered on identifying imaging features and liquid biopsy biomarkers capable of detecting PDAC and its high‐grade precursors before clinical symptoms ...
Christine Worthington +105 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 10, October 2026.ABSTRACT Circulating tumor DNA (ctDNA) is a promising biomarker for disease monitoring, yet evidence of its clinical utility in routine care remains limited. We evaluated the utility of serial ctDNA monitoring using digital PCR (ddPCR) for detecting acquired resistance (AR) and monitoring response in metastatic non‐small cell lung cancer (NSCLC) and ...
Franciele Hinterholz Knebel +26 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 10, October 2026.ABSTRACT Joint modeling (JM) of longitudinal and time‐to‐event (TTE) data is a powerful statistical technique that elucidates how temporal changes in a biomarker relate to TTE outcomes while accounting for study confounders. The growing use of next‐generation sequencing (NGS) in precision oncology, particularly in capturing circulating tumor DNA (ctDNA)
Christopher R. Pretz +9 more
wiley +1 more source
Practical Laboratory MedicineBackground: Bloodstream infections (BSIs) caused by bacteria, viruses, and parasites pose a global health challenge, with high mortality rates. Traditional blood cultures are considered the gold standard but are limited by long turnaround times, low ...
Qichuan Fu +8 more
doaj +1 more source
Cancer Reports, Volume 9, Issue 10, October 2026.ABSTRACT Background Gallbladder cancer (GBC) is a biologically complex malignancy arising from the epithelial lining of the gallbladder, with adenocarcinoma constituting the major histological subtype. Early detection is challenging because of vague clinical manifestations and the organ's deep‐seated anatomical location, resulting in diagnosis at ...
Nisha Manav +4 more
wiley +1 more source
A Serum lncRNA Signature Determines Oncogenic YAP Activity in Cancer Patients
International Journal of Cancer, Volume 159, Issue 7, Page 1829-1843, 1 October 2026.Long non‐coding RNAs (lncRNAs) signatures are promising cancer biomarkers, since their dysregulation in tumors is reflected in body fluids. In this study, next‐generation sequencing, bioinformatics, and gene expression data were combined to investigate an lncRNA signature linked specifically to the cancer‐promoting YAP in several cancer types ...
Fabian Rose +24 more
wiley +1 more source
The importance of gene polymorphism in familial inheritance of endometriosis
International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 93-105, October 2026.Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik +4 more
wiley +1 more source