Results 121 to 130 of about 23,420 (253)
Substantial variation in plasma cfDNA levels among healthy individuals.
, 2019 (A) Dot plot overlaid by a box plot showing plasma cfDNA concentrations measured by Qubit fluorometer in nanograms (ng/ml) for all the samples (n = 275).
Serdar Coskun (738308) +6 more
core +1 more source
Акушерство, гинекология и репродукцияIntroduction. Currently, non-invasive prenatal testing (NIPT) is widely used to assess a risk of fetal chromosomal anomalies. NIPТ accuracy depends on the cell-free fetal DNA (cffDNA) percentage relative to total cell-free DNA in the pregnant woman's ...
E. S. Vashukova +6 more
doaj +1 more source
Cancer Science, EarlyView.Clinical application scenarios for the diagnosis of BC. A schematic diagram illustrating the use of sEV DNA liquid biopsy technology to differentiate between benign and bladder cancer patients. ABSTRACT Existing diagnostic technologies for bladder cancer (BC) suffer from low sensitivity, low specificity, or a lack of validation.
Tao Wang +13 more
wiley +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Several benign, inflammatory and malignant lesions can present as iris or anterior chamber masses, including iris naevi, cysts, adenomas, leiomyomas, nodules, vascular tumours, melanomas, metastases, as well as iris and pigment epithelium adenocarcinomas. Fortunately, benign iris lesions are much more common than malignant tumours and many can
Charles N. J. McGhee +3 more
wiley +1 more source
Cell Proliferation, EarlyView.This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo +5 more
wiley +1 more source
Cell Proliferation, EarlyView.Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao +7 more
wiley +1 more source
Plasma cfDNA levels are significantly elevated in cancer patients.
, 2019 Plasma cell-free DNA (cfDNA) was isolated from breast (n = 26) and ovarian cancer (n = 64) patients with various stages and undergoing treatment. Female subjects (n = 50) from healthy individuals of a similar age were selected as controls for breast and ...
Serdar Coskun (738308) +6 more
core +1 more source
Cytopathology, EarlyView.This review explores liquid biopsy as a complementary approach to tissue‐based PD‐L1 assessment in advanced NSCLC treated with immune checkpoint inhibitors. Focusing on circulating tumour cells, extracellular vesicles, and circulating tumour DNA, it summarises current evidence, technical challenges, and future perspectives for personalised ...
R. Leporati +15 more
wiley +1 more source
reservedCancer is fundamentally a genetic disease; therefore, molecular characterization is essential for accurate diagnosis and treatment choice. Due to the genetic complexity of cancer, advanced technologies such as next-generation sequencing (NGS) are
BOSCOLO BRAGADIN, CHIARA
core
Comparison of cfDNA CNVs and tumor tissue CNVs.
, 2018 A) Distribution of direct correlation between CNVs detected via cfDNA samples and CNVs identified in parent tumor tissue (Red); darker color represents higher stage (1–4).
Bhuvan Molparia (4233709) +4 more
core +1 more source