Results 141 to 150 of about 23,420 (253)

Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1575-1588, July 2026.
CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin   +3 more
wiley   +1 more source

Factors affecting cfDNA test failure (univariate analysis).

open access: yes
Factors affecting cfDNA test failure (univariate analysis).
Tomas Sladecek (18121408)   +9 more
core   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An   +4 more
wiley   +1 more source

Plasma cfDNA is highly degraded.

open access: yes, 2019
(A) Box blot displaying sample plasma cfDNA copies measured by real-time PCR (copies/ml) median; vertical bar, 2701 and 1406) (n = 161) for both 79 bp and 148 bp fragments, respectively and (B) a scatter plot showing a positive linear correlation (r = 0 ...
Serdar Coskun (738308)   +6 more
core   +1 more source

Dynamics of Circulating Tumor DNA (ctDNA) Predict Treatment Efficacy and Prognosis in Patients With Advanced Pancreatic Cancer: A Prospective Large‐Cohort Study

open access: yesMedComm, Volume 7, Issue 7, July 2026.
A total of 127 advanced pancreatic ductal adenocarcinoma (PDAC) patients receiving first‐line therapy were enrolled in this study. A series of peripheral blood collected before the initiation of treatment (B1), at the first response assessment (B2), and at subsequent timepoints to perform high‐depth next‐generation sequencing.
Tingting You   +9 more
wiley   +1 more source

Chemical and Technological Aspects of Magnetic Particles for Cancer Liquid Biopsy Applications

open access: yesChemistryOpen, Volume 15, Issue 7, July 2026.
Magnetic bead engineering for liquid biopsy diagnostics reviews advances in magnetic bead design for the selective enrichment of circulating tumor DNA (ctDNA), circulating tumor cells (CTCs), and extracellular vesicles (EVs) from complex biofluids.
Beatriz Naranjo‐Martínez   +9 more
wiley   +1 more source

Society for Maternal‐Fetal Medicine Statement: Evaluation and management of cell‐free DNA screening for fetal red cell antigen genotype in alloimmunized and non‐alloimmunized pregnancies

open access: yesPregnancy, Volume 2, Issue 4, July 2026.
Abstract A substantial portion of RhD‐negative pregnant patients carry an RhD‐negative fetus and are not at risk of RhD alloimmunization. Knowing the fetal RhD genotype allows such patients to avoid unnecessary monitoring or treatment. The use of cell‐free DNA (cfDNA) to detect the fetal RhD genotype from maternal blood has been proposed to identify ...
Society for Maternal‐Fetal Medicine (SMFM)   +8 more
wiley   +1 more source

Genetic Predictors of Progression and Skin Rash in Japanese mCSPC Patients Treated With Apalutamide: CUARTET Study

open access: yesCancer Science, Volume 117, Issue 7, Page 1985-1995, July 2026.
In patients with mCSPC treated with apalutamide plus ADT, baseline ctDNA predicted earlier progression to CRPC and worse overall survival. Exploratory genome‐wide analysis identified 12 SNPs associated with apalutamide‐related skin rash. ABSTRACT Despite promising evidence of the efficacy of the androgen deprivation therapy (ADT) plus apalutamide in ...
Masaki Shiota   +8 more
wiley   +1 more source

Female endurance athletes show a reduced plasma cell‐free DNA response to all‐out and 3‐h cycling compared to male counterparts

open access: yesPhysiological Reports, Volume 14, Issue 13, July 2026.
Abstract This study investigated cell‐free DNA (cfDNA) kinetics during an all‐out and 3‐h cycling protocol, focusing on sex differences. Eighteen participants (9 women, 9 men) performed a VO2max test on a cycling ergometer. One to four weeks thereafter, 17 participants completed 3‐h cycling at an intensity 5% below their first ventilatory threshold ...
Kira Enders   +7 more
wiley   +1 more source

DNA From Neutrophil Extracellular Traps Restricts Group 3 Innate Lymphoid Cells Function in Intestinal Epithelial Repair via CCDC25

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
DNA from neutrophil extracellular traps (NET‐DNA) restricts the function of IL‐22‐dependent ILC3s in intestinal defense through coiled‐coil domain containing protein 25 (CCDC25), which hinders the repair of intestinal epithelial cells and promotes the progression of UC.
Bo Xu   +14 more
wiley   +1 more source

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