Results 151 to 160 of about 23,420 (253)

Concordance between tumor-tissue analysis and cfDNA analysis (n = 85).

, 2015
*: two out of these four patients presented unmatched mutations in tissue and plasma: they showed KRAS G12V mutations by plasma analysis and were determined either G12D or G13D by tumor tissue analysis.cfDNA: cell-free DNA; WT: wild type; SE: sensitivity;
Martina Montagnana (238579), Anna Maria Minicozzi (735347), Felice Pasini (735351), Gabriel Lima-Oliveira (5663368), Gian Cesare Guidi (658129), Elisa Danese (238583), Giuseppe Lippi (645146), Marco Benati (735348), Elisa Paviati (735349), Gian Luca Salvagno (658126), Milena Gusella (735350)   +10 more
core   +1 more source

Detection of MSI signals from peripheral blood for monitoring response to immune checkpoint blockade therapy in patients with advanced microsatellite‐unstable gastrointestinal cancers: A pilot study

International Journal of Cancer, Volume 158, Issue 12, Page 3312-3323, 15 June 2026.
What's new? A substantial proportion of patients with microsatellite‐unstable gastrointestinal adenocarcinomas do not benefit from immunotherapy. This study demonstrates that microsatellite instability can be reliably detected in plasma‐derived extracellular vesicle DNA from patients with microsatellite‐unstable gastrointestinal cancers.
Aysel Ahadova, Lena Bohaumilitzky, Thomas Walle, Joscha A. Kraske, Mirjam Tariverdian, Ulrike Ganserer‐Schmitt, Ingrid Hausser‐Siller, Vera Fuchs, Nina Nelius, Gizem Mehtap Erisen, Johannes Gebert, Albrecht Stenzinger, Dirk Jäger, Magnus von Knebel Doeberitz, Georg Martin Haag, Elena Busch, Matthias Kloor   +16 more
wiley   +1 more source

Factors affecting cfDNA test failure (univariate and multivariate analysis).

Factors affecting cfDNA test failure (univariate and multivariate analysis).
Tomas Sladecek (18121408), Gabriel Minarik (2512540), Tomas Szemes (4780383), Martina Sekelska (18121411), Andrej Gnip (9306193), Natalia Forgacova (15253813), Jaroslav Budis (837494), Michaela Hyblova (837491), Juraj Gazdarica (4780389), Marcel Kucharik (9306190)   +9 more
core   +1 more source

Mechanistic Modeling of cfDNA Fragmentome Dynamics Predicts Progression to Immunotherapy

BackgroundPlasma cell-free DNA (cfDNA) shows promise as predictive cancer biomarker, but mechanisms governing cfDNA production/fragmentation/elimination dynamics, and their relationships with tumor burden and disease progression, remain poorly understood.
Boutonnet, Audrey, Salas, Sebastien, Nguyen Phuong, Linh, Tomasini, Pascale, Greillier, Laurent, Garcia, Jean-Charles, Ginot, Frédéric, Deville, Jean-Laurent, Fina, Frédéric, Benzekry, Sébastien   +9 more
core   +1 more source

Prediction of methylation status using WGS data of plasma cfDNA for multi-cancer early detection (MCED)

Background Cell-free DNA (cfDNA) contains a large amount of molecular information that can be used for multi-cancer early detection (MCED), including changes in epigenetic status of cfDNA, such as cfDNA fragmentation profile.
Pin Cui, Weihuang He, Hanming Lai, Xiaozhou Zhou, Yong Xiong, Mingji Feng, Yi Pan, Shu Xu, Chuxin Zhang, Tingmin Chang, Guozeng Huang   +10 more
core   +1 more source

Detection of recurrence of HPV-driven oropharyngeal cancer by HPV cell-free DNA. [PDF]

Sci Rep
Fricke NM, Guarda V, Höfler D, Waterboer T, Schouten CS, Ikenberg K, Schroeder L, Rosing F, Broglie Daeppen MA.   +8 more
europepmc   +1 more source

Holistic ends of cfDNA analysis

Initial ...
openaire   +1 more source

Agreement between the Roche cfDNA tubes and K2EDTA tubes.

Agreement between the Roche cfDNA tubes and K2EDTA tubes.
Jason Lai (44092), Theresa May (18334177), Sidney Scudder (12475550), Snehal Joshi (18334189), Michelle S. Clement (9560905), Alexander Kohlmann (76969), Patrick O’Donnell (3557501), Peter Meldgaard (4858900), Xiaocheng Li-Sucholeiki (15014244), Milena Kohlmann (18334183), Harkanwal Halait (18334180), Neelima Shrestha (18334192), Marilyn Kiral (18334195), Nitta Lee (18334186), Boe Sorensen (4858906)   +14 more
core   +1 more source

Reduction in Donor-Derived Cell-Free DNA After Rejection Treatment is Associated With Improved Long Term Allograft Function. [PDF]

Clin Transplant
Schumacher L, Philippart O, Yau J, Shuaib F, Paluri S, Castellanos AL, Schadler A, Fattah H.   +7 more
europepmc   +1 more source

Early Postoperative Cell-Free DNA Reflects Renal and Hepatic Injury After Pediatric Cardiac Surgery. [PDF]

J Cardiovasc Dev Dis
Abuelhija H, Mandel A, Watad S, Zemmour H, Keizman E, Mishaly D, Arfi Levy E, Serraf AE, Pollak U.   +8 more
europepmc   +1 more source