Results 121 to 130 of about 24,434 (294)

Optical parametric generation in CGA crystal [PDF]

, 2002
K. L. Vodopyanov, G.M.H. Knippels, A. F. G. van der Meer, J.P. Maffetone, Ilya Zwieback   +4 more
openalex   +1 more source

cGAS activation in phased droplets [PDF]

Cell Research, 2018
Yongbo Liu, Richard A. Flavell, Richard A. Flavell, Hua-Bing Li   +3 more
openaire   +3 more sources

Decoy DNA protects molecular tension probes from DNase degradation

Angewandte Chemie International Edition, Accepted Article.
DNA‐based molecular probes are essential tools for visualizing and quantifying mechanotransduction at the single‐molecule level. However, their application in live‐cell environments is severely limited by DNase‐mediated degradation, which shortens probe lifespan and introduces false‐positive signals.
Hongyuan Zhang, Seong Ho Kim, Isaac T.S. Li   +2 more
wiley   +1 more source

Viral protease binds to nucleosomal DNA and cleaves nuclear cGAS that attenuates type I interferon

mBio
Nuclear cyclic GMP-AMP synthetase (cGAS) binds to nucleosome with high affinity to prevent its activation by self-DNA. Upon stimulation with double-stranded DNA, cGAS is activated and translocates from the nucleus to the cytoplasm, guided by its N ...
Lei Wu, Ya Yan, Ye Yuan, Zhenchao Zhao, Weiyu Qu, Xiangyu Huang, Haiwei Wang, Pingwei Li, Xin Li   +8 more
doaj   +1 more source

−1 Frameshifting at a CGA AAG Hexanucleotide Site Is Required for Transposition of Insertion Sequence IS 1222 [PDF]

, 2004
Nina Mejlhede, Patricia Licznar, Marie-Françoise Prère, Norma M. Wills, Raymond F. Gesteland, John F. Atkins, Olivier Fayet   +6 more
openalex   +1 more source

cGAS-STING signaling in cardiovascular diseases

Frontiers in Immunology
Sterile inflammation, characterized by a persistent chronic inflammatory state, significantly contributes to the progression of various diseases such as autoimmune, metabolic, neurodegenerative, and cardiovascular disorders. Recent evidence has increasingly highlighted the intricate connection between inflammatory responses and cardiovascular diseases,
Qianxin Zhang, Qianxin Zhang, Qianxin Zhang, Lijuan Shen, Hongbiao Ruan, Zhouqing Huang, Zhouqing Huang   +6 more
openaire   +3 more sources

Proteomic Profiling of the Large‐Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling

Arthritis &Rheumatology, EarlyView.
Objective Takayasu arteritis (TAK) and giant cell arteritis (GCA), the most common forms of large‐vessel vasculitis (LVV), can result in serious morbidity. Understanding the molecular basis of LVV should aid in developing better biomarkers and treatments. Methods Plasma proteomic profiling of 184 proteins was performed in two cohorts. Cohort 1 included
Robert T. Maughan, Erin Macdonald‐Dunlop, Lubna Haroon‐Rashid, Louise Sorensen, Natalie Chaddock, Shauna Masters, Andrew Porter, Marta Peverelli, Charis Pericleous, Andrew Hutchings, James Robinson, Taryn Youngstein, Raashid A. Luqmani, Justin C. Mason, Ann W. Morgan, James E. Peters   +15 more
wiley   +1 more source

Abstracts from the 11th Annual Meeting of the Collaborative Group of the Americas on Inherited Colorectal Cancer (CGA-ICC), October 21–22, 2007, La Jolla, California, USA [PDF]

, 2007
Petersson Po, Oh H--K Ko Oo, Kimberly Oh, Min‐Hoe Chew, Carol Loi, Choong‐Leong Tang, Kong‐Weng Eu, MA Ya-na, Michael D. Johnson, N Brown, Carol A. Burke, James M. Church, R. Matthew Walsh, Jackson Ia, Sel'kov Sa, Jon D. Vogel, Matthew F. Kalady, Jo Oo, Sreeranga N, Ziqiang Yuan, Prashanth Sreeramoju, Tara S. Kent, Winfred Edelman, Kenneth Fordyce, Victoria Lai, Kara Fordyce, Noam White, Thomas Weber, Kenneth Fordyce, Ajay Goel, Takeshi Nagasaka, Jennifer L. Spiegel, Sheryl Livingston, Richard L. Meyer, Warren E. Lichliter, Rebarbar Ri, Bo Ol La, Francesca Molinari, Federica Perrone, Andrea Lampis, P. Sala, Chiara Bassi, Michele Sardella, Paolo Radice, Marco A. Pierotti, Milo Frattini, Silvana Pilotti, L.Z. Lu   +47 more
openalex   +1 more source

CGA Research Summit: 2016 Research

, 2016
The overall objective of this research was to provide insight into how Canadian casinos can improve the overall offer to not only keep their current visitors returning, but to also appeal to those who are not currently visiting. Includes: Section A. Casino Attitudes and Participation; Section B. Lottery Participation; Section C.
Canadian Gaming Association, Ipsos
openaire   +3 more sources

Loss of TRIM21 drives UVB‐induced systemic inflammation by regulating DNA‐sensing pathways

Arthritis &Rheumatology, Accepted Article.
Background Patients with systemic lupus erythematosus (SLE) experience photosensitivity, with exposure to ultraviolet light B (UVB) driving lupus flares and triggering symptoms like joint pain, fatigue, and cutaneous lesions. Although the mechanism(s) linking UVB exposure to systemic effects are unclear, type I interferons (IFNs) are known to play a ...
Gantsetseg Tumurkhuu, Graziela Perri, Richard Moore, Lihong Huo, Arati Naveen Kumar, Richard Ainsworth, Trinitee Oliver, Gabriela de los Santos, David Gibb, Jessica Carriere, Jeong Min Yu, Rachel Abuav, Lindsy Forbess, Daniel J. Wallace, Mariko Ishimori, Wonwoo Shon, Christian Stehlik, Caroline A. Jefferies   +17 more
wiley   +1 more source