Results 131 to 140 of about 24,434 (294)

Construction and Characterization of Novel Shuttle Expression Vectors for Actinobacillus succinogenes

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Actinobacillus succinogenes is a ruminal microorganism of biotechnological importance due to its capacity to produce succinic acid at high yields. Despite the scientific interest in this organism, molecular vehicles for the transfer and expression of genetic material are limited compared to the existing demand.
Angélica Vallejo‐Giraldo   +7 more
wiley   +1 more source

Approaches to repurposing reverse transcriptase antivirals in cancer

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head   +2 more
wiley   +1 more source

MYC: The Guardian of Its Own Chaos

open access: yesBioEssays, EarlyView.
MYC is an oncogene that drives tumorigenesis through enhanced transcription and replication. Paradoxically, MYC induces transcriptional and replicative stress and acts as a resilience factor against these stressors. We discuss how MYC balances these stressors to promote tumor growth while evading immune detection and propose strategies to target MYC ...
Abdallah Gaballa   +2 more
wiley   +1 more source

Levels of awakening salivary CgA in response to stress in healthy subjects [PDF]

open access: gold, 2010
Rei Den   +3 more
openalex   +1 more source

Transcription‐Replication Conflicts: Unlocking New Frontiers in Cancer

open access: yesBioEssays, EarlyView.
Transcription‐replication conflicts (TRCs) constitute a major source of genome instability. Such conflicts are regulated by chromatin, its dysfunction causing replication stress, DNA breaks, and mutations frequently found in cancer. We review the molecular basis of TRCs and chromatin regulation and discuss the clinical potential of targeting TRCs as ...
Aleix Bayona‐Feliu, Andrés Aguilera
wiley   +1 more source

Antibacterial hydrogel: The sniper of chronic wounds

open access: yesBMEMat, EarlyView.
The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian   +6 more
wiley   +1 more source

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