Results 141 to 150 of about 34,737 (190)

High cGAS-STING expression associates with improved efficacy of neoadjuvant chemo-immunotherapy in head and neck squamous cell carcinoma

Frontiers in Oncology
PurposeNeoadjuvant chemo-immunotherapy (NACI) has demonstrated significant clinical advantages in head and neck squamous cell carcinomas (HNSCC), while clinical responses vary in different patients.
Miao Wang, Menglin Shi, Yiming Ding, Zishanbai Zhang, Yuze Ge, Zhixin Li, Yixin Jing, Honglian Hu, Xiaohong Chen   +8 more
doaj   +1 more source

cGAS activation in phased droplets [PDF]

Cell Research, 2018
Yongbo Liu, Richard A. Flavell, Richard A. Flavell, Hua-Bing Li   +3 more
openaire   +3 more sources

The Role of Wage and Skill Differences in US-German Employment Differences [PDF]

Greater job creation in the US than in Germany has often been related to greater wage dispersion coupled with less regulated labour and product markets in the US.
Richard B. Freeman, Ronald Schettkat
core  

cGAS-STING signaling in cardiovascular diseases

Frontiers in Immunology
Sterile inflammation, characterized by a persistent chronic inflammatory state, significantly contributes to the progression of various diseases such as autoimmune, metabolic, neurodegenerative, and cardiovascular disorders. Recent evidence has increasingly highlighted the intricate connection between inflammatory responses and cardiovascular diseases,
Qianxin Zhang, Qianxin Zhang, Qianxin Zhang, Lijuan Shen, Hongbiao Ruan, Zhouqing Huang, Zhouqing Huang   +6 more
openaire   +3 more sources

Viral protease binds to nucleosomal DNA and cleaves nuclear cGAS that attenuates type I interferon

mBio
Nuclear cyclic GMP-AMP synthetase (cGAS) binds to nucleosome with high affinity to prevent its activation by self-DNA. Upon stimulation with double-stranded DNA, cGAS is activated and translocates from the nucleus to the cytoplasm, guided by its N ...
Lei Wu, Ya Yan, Ye Yuan, Zhenchao Zhao, Weiyu Qu, Xiangyu Huang, Haiwei Wang, Pingwei Li, Xin Li   +8 more
doaj   +1 more source

cGAS liquid droplets [PDF]

Nature Immunology, 2018
openaire   +3 more sources

Skill Compression, Wage Differentials and Employment: Germany vs. the US [PDF]

Germany's more compressed wage structure is taken by many analysts as the main cause of the German-US difference in job creation. We find that the US has a more dispersed level of skills than Germany but even adjusted for skills, Germany has a more ...
Richard B. Freeman, Ronald Schettkat
core  

Mn potentiates cGAS [PDF]

Nature Immunology, 2018
openaire   +3 more sources

cGAMP-activated cGAS–STING signaling: its bacterial origins and evolutionary adaptation by metazoans

Nature Structural & Molecular Biology, 2023
D. Patel, You Yu, W. Xie
semanticscholar   +1 more source

Autonomous virulence adaptation improves coevolutionary optimization [PDF]

, 2011
Ait-Boudaoud, D, Cartlidge, J
core   +1 more source