Results 171 to 180 of about 24,434 (294)

O-53 A study of the value of comprehensive geriatric assessment (CGA) in older women with primary breast cancer – Preliminary results

, 2010
Louise Hall, Siau-Wei Tang, Arti Hurria, L. Winterbottom, Hilda Kennedy, D.A.L. Morgan, Davina Porock, Kwok‐Leung Cheung   +7 more
openalex   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Inflammatory Bowel Disease (IBD)-Associated Colorectal Cancer (CRC): Is cGAS-STING Pathway Targeting the Key to Chemoprevention? [PDF]

Int J Mol Sci
Papadakos SP, Georgiadou C, Argyrou A, Michailidou E, Thanos C, Vogli S, Siakavellas SI, Manolakopoulos S, Theocharis S.   +8 more
europepmc   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Chromogranin A (CgA) as Poor Prognostic Factor in Patients with Small Cell Carcinoma of the Cervix: Results of a Retrospective Study of 293 Patients

, 2012
Ling-Min Liao, Xin Zhang, Yufeng Ren, Xiao-Ying Sun, Na Di, Nan Zhou, Ruike Pan, Shuhua Ma, Lixue Zhou   +8 more
openalex   +2 more sources

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Interdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa, Ke‐wei Zhao   +6 more
wiley   +1 more source

Astilbin Alleviates IL-17-Induced Hyperproliferation and Inflammation in HaCaT Cells via Inhibiting Ferroptosis Through the cGAS-STING Pathway. [PDF]

Int J Mol Sci
Xu X, Zhang H, Chang A, Peng H, Li S, Zhang K, Wang W, Yin X, Qu C, Dong X, Ni J.   +10 more
europepmc   +1 more source

Exploring the Role of T‐Cell Metabolism in Modulating Immunotherapy Efficacy for Non‐Small Cell Lung Cancer Based on Clustering

Journal of Clinical Laboratory Analysis, EarlyView.
We conducted a comprehensive investigation of the metabolic profiles of infiltrating T cells in NSCLC tumors and found metabolic heterogeneity in three T‐cell subtypes, which are associated with the prognosis of ICB therapy. We defined these metabolic clusters as response‐dependent (R) clusters and non‐response‐dependent (NR) clusters, and elucidated ...
Hongzhe Guo, Liangyu Zhang, Hu Tang, Peiwen Liu, Bin Hu, Yue Gong, Rui Hou, Ziheng Wu   +7 more
wiley   +1 more source

Attachment representations in pre‐adolescents at familial high risk of schizophrenia or bipolar disorder and population‐based controls—Characteristics of attachment from middle childhood to pre‐adolescence, and its relation to parental functioning and child mental disorder

JCPP Advances, EarlyView.
Pre‐adolescent attachment, predictors related to caregiving, and middle childhood attachment predictors of pre‐adolescent mental disorders was assessed in a cohort of children of parents with schizophrenia or bipolar and population‐based controls.
Mette Falkenberg Krantz, Maja Gregersen, Lotte Veddum, Carsten Hjorthøj, Åsa Kremer Prøsch, Jessica Ohland, Julie Marie Brandt, Sinnika Birkehøj Rohd, Christina Bruun Knudsen, Anna Krogh Andreasen, Nicoline Hemager, Aja Greve, Ole Mors, Merete Nordentoft, Elia Psouni, Anne A. E. Thorup   +15 more
wiley   +1 more source

Role of MS4A7 in Regulating Microglial Polarization and Neuroinflammation in Spinal Cord Injury via the cGAS-STING-NLRP3 Axis. [PDF]

CNS Neurosci Ther
Li X, Liu J, Deng Y, Xing F, Lu X, Zhang Z, Li C.   +6 more
europepmc   +1 more source